BrainRegionLPC SC PH CL

Clarke Nucleus

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This page covers biological details of component Clarke Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Spinal Cord -> Posterior/Dorsal Horn (BMA.SC.PH) -> Lamina V, VI (BMA.SC.PH.L56) -> Clarke Nucleus (LPC.SC.PH.CL) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Lower Brain - Peripheral Control Area (LPC)
• Area circuit: Unconscious Cerebellar Sensations (SU)
• Role: processor.automatic
• Function: Unconscious Proprioception
• Notes to function:
  • To CR

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Components

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Component items:

• Clarke's Nucleus of Lumbar Spinal Cord
• Clarke's Nucleus of Thoracic Spinal Cord

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
LLC	LLC.MM.RD.MG	Magnocellular Part of Red Nucleus	excitatory-glu	uncertain	(unknown reference)
LPC	LPC.PN.SG.LDRG	Lower Dorsal Root Ganglion	excitatory-glu	uncertain	(unknown reference)
	LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	excitatory-glu	uncertain	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
LLC	LLC.HL.ARC	Arcuate Nucleus of Medulla	excitatory-glu	uncertain	(unknown reference)
	LLC.HT.CR.PV	Cerebellar Paravermis	excitatory-glu	uncertain	Afferent pain pathways (SC -> Cerebellum, abstract)
	LLC.HT.PN.PBB	Pontobulbar Body	excitatory-glu	uncertain	(unknown reference)
LRC	LRC.MM.CNF	Cuneiform Nucleus	excitatory-glu	uncertain	(unknown reference)

Thirdparty Circuits

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• Afferent pain pathways - see Reference (CF.PAIN-PATH)

ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AMY=Amygdala,FAM.FT.AM
BG=Basal Ganglia,FEC.FT.BG
Cerebellum=Cerebellar Complex,LLC.HT.CRC
Insula=Insular Cortex,NC.INS
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PFC=Prefrontal Cortex,NC.AL.PFC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2
SC=Posterior/Dorsal Horn,BMA.SC.PH
Thalamus=Sensory Thalamus,FD.TH.SR

• Cerebellum functional divisions - see Reference (CM.CR-DECUSSATION)

CCV=Central Cervical Nucleus,LPC.SC.IZ.CCV
CRP=Cerebellar Lateral Lobe,LLC.HT.CR.CC
CRS=Cerebellar Paravermis,LLC.HT.CR.PV
CRV=Cerebellar Vermis,LRC.HT.CR.VM
CTX=Anterior Lobe,NC.LOBE.ANT
DN=Dentate Nucleus,LLC.HT.CR.DN
FG=Fastigual Nucleus,LRC.HT.CR.FG
IO=Inferior Olivary Nucleus,LLC.HL.IO
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
PNN=Basilar Pontine Nuclei,LLC.HT.BPN
RD=Red Nucleus,LLC.MM.RD
RF=Pontine Reticular Formation,HT.RF
SCM=Anterior/Ventral Horn,SC.VH
SCS=Proprius Nucleus,LPC.SC.PH.NP
SCSD=Clarke Nucleus,LPC.SC.PH.CL
VB=Vestibular Nuclei,LPC.HT.VBN
VBG=Vestibular Ganglion,LPC.PN.SG.VB
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL

References

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• http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html
• http://instruct.uwo.ca/anatomy/530/cblm.htm