BiologicalArchitectureModulation

Biological Life Research

This page covers biological principles of non-specific modulation.

Overview

mind contains components which affect large mind areas at once
these components are affected by quite specific circuits and change the mode in which brain is operating
components are utilizing specific neurotransmitters - DA, 5HT, ACh, NE for its efferent connections
non-specific modulators allow the mind to work as a single unit, by means of coordinating internals parts
sample behavior of modulators:
- DA circuit to speed up execution: habenula -> SNc -> striatum (D1+,D2-) -> ventroanterior thalamus (reduce inhibition) -> M1 (increased activity) -> motoneuron
- 5HT circuit to go asleep: habenula -> dorsal raphe nucleus -> paraventricular thalamus -> hypothalamus -> body
- ACh circuit to control perception vs imaginaton: amygdala -> basal nucleus of Meynert -> prefrontal cortex (-feedforward,+feedback)
- NE circuit to adopt to pain: spinal cord substantia gelatinosa -> lateral spinal nucleus -> hypothalamus -> locus coeruleus -> spinal cord substantia gelatinosa (inhibit)