BrainAreaFAM

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Forebrain Affective Motivations Area

Home -> BiologicalLifeResearch -> BrainAreaFAM


Local Circuits

(generated)

ID Name Regions
FAMXAA Acquisition of Avoidance Responses FAM.FD.LHB.LT, FAM.FD.LHB.MED
FAMXCEC Conscious Emotions Control FAM.FT.AM.BP, FAM.FT.AM.ITC, FAM.FT.SEP.SF, FAM.FT.SEP.TR
FAMXCS Conditional Context Sensory Data and Memory Attention FAM.FD.TH.PT, FAM.FT.AM.AB, FAM.FT.AM.BM, FAM.FT.AM.COA, FAM.FT.AM.LADL
FAMXEFL Express Flight Emotions FAM.FT.AM.MEA, FAM.FT.AM.MPD, FAM.FT.AM.MPV, FAM.FT.BNST, FAM.FT.IPAC.MED, FAM.FT.SEP.BAC
FAMXEFT Express Fight Emotions FAM.FT.AM.CEM, FAM.FT.SEP.SH
FAMXFFD Solving Fight-Flight Dilemma FAM.FT.SEP.LT
FAMXMF Memory Formation Affective Focus FAM.FT.SEP.DBB, FAM.FT.SEP.MED
FAMXREC Reward Emotions Control FAM.FD.MHB, FAM.FT.EPF, FAM.HP.NI, FAM.HP.PPN.IPD, FAM.HP.PPN.RMTG
FAMXUS Fast Unconditional Sensory Data and Association Memory FAM.FT.AM.CEC, FAM.FT.AM.CEL, FAM.FT.AM.COP, FAM.FT.AM.LAVL, FAM.FT.AM.LAVM

Acquisition of Avoidance Responses

unavailable

Component ID Component Name Type Service Function Comments
FAM.FD.LHB.LT Lateral Habenula Lateral Part nucleus FAU Encoding negative feedback, direct, Pallidal
FAM.FD.LHB.MED Lateral Habenula Medial Part nucleus FAU Encoding negative feedback, direct, Septal

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Subcortical
FAM FAM.FD.LHB.MED FAM.FD.MHB Medial Habenula nucleus-nucleus (unknown reference)
FAM.HP.NI Incertus Nucleus nucleus-nucleus-gaba (unknown reference)
FEC FAM.FD.LHB.LT FEC.FT.GPI.DS Globus Pallidus Internal Dorsal nucleus-nucleus-gaba [Connections (GPi -> LHb, abstract)]
FAM.FD.LHB.MED FEC.FT.VP.VM Ventral Pallidum Ventromedial nucleus-nucleus-gaba (unknown reference)
LAC FAM.FD.LHB.LT LAC.FD.HT.LTN Lateral Hypothalamic Nucleus nucleus-nucleus [Connections (LH -> LHb, abstract)]
LAC.FD.HT.PO Preoptic Nucleus nucleus-nucleus [Connections (LPO -> LHb, abstract)]
LMC FAM.FD.LHB.LT LMC.MM.RF.SUC Superior Central Raphe Nucleus nucleus-nucleus-5HT (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FAM FAM.FD.LHB.LT FAM.HP.PPN.RMTG Rostromedial Tegmental Nucleus nucleus-nucleus [and its network (LHB -> RMTG, abstract)]
FEC FAM.FD.LHB.MED FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral nucleus-nucleus [Connections (LHb -> SNc, abstract)]
LMC FAM.FD.LHB.MED LMC.HP.TG.DTG Dorsal Tegmental Nucleus nucleus-nucleus (unknown reference)
LMC.HP.TG.VTG Ventral Tegmental Nucleus nucleus-nucleus (unknown reference)
LMC.MM.RF.SUC Superior Central Raphe Nucleus nucleus-nucleus [Connections (LHb -> MR, abstract)]
LMC.MM.RP.DRN Dorsal Raphe Nucleus nucleus-nucleus [Connections (LHb -> DR, abstract)]

Conscious Emotions Control

unavailable

Component ID Component Name Type Service Function Comments
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus nucleus FAU enhance explicit memories in hippocampus about emotional situations
FAM.FT.AM.ITC Intercalated Amygdaloid Nuclei nucleus FAU inhibit excessive emotional behavior inhibitory
FAM.FT.SEP.SF Septofimbrial Nucleus nucleus FAU afferent to medial habenula, primary input to indirect encoding negative feedback
FAM.FT.SEP.TR Triangular Septal Nucleus nucleus FAU afferent to medial habenula, interpeduncular nucleus

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NDM FAM.FT.AM.BP NDM.NC.AL.DACG Dorsal Anterior Cingulate Area neocortex-nucleus [for serotonin in moral behavior (ACG -> AMY, abstract)]
NDM.NC.AL.FPC Lateral Frontopolar Cortex neocortex-nucleus (unknown reference)
NDM.NC.AL.VACG Ventral Anterior Cingulate Area neocortex-nucleus [for serotonin in moral behavior (ACG -> AMY, abstract)]
FAM.FT.AM.ITC NDM.NC.AL.DMPFC Dorsomedial Prefrontal Cortex neocortex-nucleus (unknown reference)
Subcortical
FAM FAM.FT.AM.BP FAM.FT.AM.LADL Dorsolateral Amygdaloid Nucleus nucleus-nucleus [and its network (LA -> BLN, abstract)]
FAM.FT.AM.LAVL Ventrolateral Amygdaloid Nucleus nucleus-nucleus [and its network (LA -> BLN, abstract)]
FAM.FT.AM.ITC FAM.FT.AM.BM Magnocellular Basal Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.LADL Dorsolateral Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.SEP.SF FAM.HP.NI Incertus Nucleus nucleus-nucleus-gaba (unknown reference)
FAM.FT.SEP.TR FAM.HP.NI Incertus Nucleus nucleus-nucleus-gaba (unknown reference)
FMM FAM.FT.SEP.SF FMM.FT.HC.CA3D Distal CA1 of Hippocampus allocortex-nucleus [Gyrus (HC -> SEP, abstract)]
FAM.FT.SEP.TR FMM.FT.HF.SUBD Distal Subiculum allocortex-nucleus [mammillary nucleus and theta rhythm (HF -> SEP, abstract)]

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FAM FAM.FT.AM.BP FAM.FT.AM.BM Magnocellular Basal Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus [and its network (BLN -> CEA, abstract)]
FAM.FT.AM.ITC FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus-gaba (unknown reference)
FAM.FT.SEP.SF FAM.FD.MHB Medial Habenula nucleus-nucleus-gaba [Connections (S -> MHb, abstract)]
FAM.FT.SEP.TR FAM.FD.MHB Medial Habenula nucleus-nucleus-gaba [Connections (S -> MHb, abstract)]
FEC FAM.FT.AM.BP FEC.FT.ACC.CORE Nucleus Accumbens Core nucleus-nucleus [and its network (BLN -> NACC, abstract)]
FMM FAM.FT.AM.BP FMM.NC.PH.LEC Lateral Entorhinal Cortex nucleus-neocortex [Connections of Hippocampus (AM -> EC, abstract)]
LMC FAM.FT.AM.BP LMC.FT.NBM Basal Nucleus of Meynert nucleus-nucleus (unknown reference)

Conditional Context Sensory Data and Memory Attention

unavailable

Component ID Component Name Type Service Function Comments
FAM.FD.TH.PT Paratenial Nucleus of Thalamus nucleus FAU Gateway for multimodal information to limbic system used in selecting appropriate
responses
Projects to BNST, AM, OMPFC, ET; Direct behavior
toward a particular outcome over a range of
outcomes
FAM.FT.AM.AB Accessory Basal Amygdaloid Nucleus nucleus FAU enhance assotiative memory formation proections to matrix of core of NACC
FAM.FT.AM.BM Magnocellular Basal Amygdaloid Nucleus nucleus FAU enhance emotional memories memories in medial prefrontal cortex
FAM.FT.AM.COA Anterior Cortical Amygdaloid Nucleus nucleus FAU olfactory processing - conditional contextual signaling
FAM.FT.AM.LADL Dorsolateral Amygdaloid Nucleus nucleus FAU conditional stimulus input - high-aggregated visual, auditory and somatic,
patterns of perception
LA2

Internal Region Connections:

Source Region Target Region Type Reference
FAM.FT.AM.COA FAM.FT.AM.AB nucleus-nucleus (unknown reference)
FAM.FT.AM.LADL FAM.FT.AM.AB nucleus-nucleus [alarm system (LA -> AB, abstract)]

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NCP FAM.FT.AM.BM NCP.NC.INS.PIC Posterior Insular Cortex neocortex-nucleus (unknown reference)
FAM.FT.AM.LADL NCP.NC.INS.PPC Peripaleocortical Claustral neocortex-nucleus (unknown reference)
NDM FAM.FT.AM.BM NDM.NC.AL.FPC Lateral Frontopolar Cortex neocortex-nucleus (unknown reference)
NSA FAM.FT.AM.LADL NSA.FD.TH.MGB Medial Geniculate Body nucleus-nucleus [disruption of prefrontal cortex (TH -> AM, abstract)]
NSA.NC.IT.TE Inferotemporal Cortex neocortex-nucleus [and its network (ITC -> LA, abstract)]
Subcortical
FAM FAM.FT.AM.AB FAM.FT.AM.LAVM Ventromedial Amygdaloid Nucleus nucleus-nucleus [alarm system (LA -> AB, abstract)]
FAM.FT.AM.BM FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.LADL FAM.FT.IPAC.MED Medial Interstitial Anterior Commissural Nucleus nucleus-nucleus (unknown reference)
FMM FAM.FT.AM.AB FMM.FT.HF.SUBD Distal Subiculum allocortex-nucleus [model of hippocampal formation anatomy (SUB -> Amyg, abstract)]
FMM.FT.HF.SUBP Proximal Subiculum allocortex-nucleus [model of hippocampal formation anatomy (SUB -> Amyg, abstract)]
FMM.NC.PH.LEC Lateral Entorhinal Cortex neocortex-nucleus [model of hippocampal formation anatomy (EC -> Amyg, abstract)]
LMC FAM.FT.AM.BM LMC.FT.NBM Basal Nucleus of Meynert nucleus-nucleus-ACh (unknown reference)
LPC FAM.FT.AM.COA LPC.FT.MOB Main Olfactory Bulb nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Cortical
NCP FAM.FD.TH.PT NCP.NC.MPL.RSC Retrosplenial Cortex nucleus-neocortex [of Diencephalon to Recognition Memory (MID -> PostCingulate, abstract)]
FAM.FT.AM.BM NCP.NC.MPL.PSCG Posterior Cingulate Cortex nucleus-neocortex [decision-making (AMYG -> CGp, abstract)]
NDM FAM.FD.TH.PT NDM.NC.AL.ROFCR Most Rostral Orbitofrontal Cortex nucleus-neocortex [Vision (Thalamus -> FrontalCortex, abstract)]
FAM.FT.AM.AB NDM.FD.TH.MDM Medial Mediodorsal Nucleus of Thalamus nucleus-nucleus [Cortex (PFC) in emotional behavior (AM -> TH, abstract)]
NDM.NC.AL.DACG Dorsal Anterior Cingulate Area nucleus-neocortex [disruption of prefrontal cortex (AM -> ACG, abstract)]
NDM.NC.AL.VACG Ventral Anterior Cingulate Area nucleus-neocortex [disruption of prefrontal cortex (AM -> ACG, abstract)]
NPE FAM.FD.TH.PT NPE.FD.TH.MPV Medial Pulvinar nucleus-nucleus [of Diencephalon to Recognition Memory (MID -> mPULV, abstract)]
NSA FAM.FT.AM.BM NSA.NC.TTG.A1 Primary Auditory Cortex nucleus-neocortex [Interactions in Tectum (AM -> AC, abstract)]
Subcortical
FAM FAM.FD.TH.PT FAM.FT.AM.LAVL Ventrolateral Amygdaloid Nucleus nucleus-nucleus [disruption of prefrontal cortex (TH -> AM, abstract)]
FAM.FT.BNST Bed Nucleus of Stria Terminalis nucleus-nucleus (unknown reference)
FAM.FT.AM.AB FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus [alarm system (AB -> CE, abstract)]
FAM.FT.AM.MPD Medial Posteror Dorsal Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.BM FAM.FT.AM.ITC Intercalated Amygdaloid Nuclei nucleus-nucleus (unknown reference)
FAM.FT.AM.LADL FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus nucleus-nucleus [and its network (LA -> BLN, abstract)]
FAM.FT.AM.CEC Central Amygdaloid Nucleus, capsular subdivision nucleus-nucleus [and its network (LA -> CEA, abstract)]
FAM.FT.AM.ITC Intercalated Amygdaloid Nuclei nucleus-nucleus (unknown reference)
FEC FAM.FD.TH.PT FEC.FT.ACC.CORE Nucleus Accumbens Core nucleus-nucleus (unknown reference)
FAM.FT.AM.AB FEC.FT.CN.TL Caudate Nucleus Tail nucleus-nucleus (unknown reference)
FMM FAM.FD.TH.PT FMM.NC.PH.LEC Lateral Entorhinal Cortex nucleus-neocortex [of Diencephalon to Recognition Memory (MID -> EC, abstract)]
FAM.FT.AM.AB FMM.NC.PH.PAS Parasubiculum nucleus-neocortex (unknown reference)
LMC FAM.FT.AM.AB LMC.FT.NBM Basal Nucleus of Meynert nucleus-nucleus (unknown reference)

Express Flight Emotions

unavailable

Component ID Component Name Type Service Function Comments
FAM.FT.AM.MEA Medial Anterior Amygdaloid Nucleus nucleus FAU olfactory processing
FAM.FT.AM.MPD Medial Posteror Dorsal Amygdaloid Nucleus nucleus FAU reproductive behavior MePD -> HT-MPN
FAM.FT.AM.MPV Medial Posteror Ventral Amygdaloid Nucleus nucleus FAU defensive behavior MePV -> LAC.FD.HT.VM (reproductive+defensive),
LAC.FD.HT.AH (defensive)
FAM.FT.BNST Bed Nucleus of Stria Terminalis nucleus FAU Mediate slow longer-lasting responses that accompany sustained threats Major output from AM to HT, part of extended
amygdala; medial part continues to medial AM,
central part continues to central AM
FAM.FT.IPAC.MED Medial Interstitial Anterior Commissural Nucleus nucleus FAU Sharp, acute pain sensation reciprocate its afferent connections, similar to
medial part of central amygdaloid nucleus;
projections to AM-Ce/BNST components, PB, and SOL
originate chiefly from medial division; strong ACh
projections from caudal IPACm to AM-BL-posterior
and amygdalopiriform transition area
FAM.FT.SEP.BAC Bed Nucleus of Anterior Commissure nucleus FAU projection to contralateral HC

Internal Region Connections:

Source Region Target Region Type Reference
FAM.FT.AM.MEA FAM.FT.AM.MPD nucleus-nucleus (unknown reference)
FAM.FT.AM.MPV nucleus-nucleus (unknown reference)
FAM.FT.BNST nucleus-nucleus (unknown reference)
FAM.FT.IPAC.MED nucleus-nucleus (unknown reference)
FAM.FT.AM.MPV FAM.FT.BNST nucleus-nucleus-gaba (unknown reference)
FAM.FT.BNST FAM.FT.IPAC.MED nucleus-nucleus (unknown reference)
FAM.FT.SEP.BAC nucleus-nucleus (unknown reference)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NCP FAM.FT.BNST NCP.NC.AL.SGCG Subgenual Cingulate Cortex neocortex-nucleus (unknown reference)
NSA FAM.FT.IPAC.MED NSA.NC.PH.PIR Piriform Cortex neocortex-nucleus (unknown reference)
Subcortical
FAM FAM.FT.AM.MEA FAM.FT.AM.COP Posterior Cortical Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.MPD FAM.FT.AM.AB Accessory Basal Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.BNST FAM.FD.TH.PT Paratenial Nucleus of Thalamus nucleus-nucleus (unknown reference)
FAM.FT.AM.CEL Central Amygdaloid Nucleus, lateral subdivision nucleus-nucleus (unknown reference)
LAC FAM.FT.BNST LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus nucleus-nucleus (unknown reference)
LPC FAM.FT.AM.MEA LPC.FT.AOB Accessory Olfactory Bulb nucleus-nucleus (unknown reference)
FAM.FT.BNST LPC.FD.TH.PV Paraventricular Nucleus of Thalamus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FAM FAM.FT.AM.MEA FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus [alarm system (MED -> CE, abstract)]
FAM.FT.AM.MPV FAM.FT.SEP.LT Lateral Septal Nucleus nucleus-nucleus-gaba (unknown reference)
FAM.FT.IPAC.MED FAM.FT.AM.LADL Dorsolateral Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.SEP.BAC FAM.FD.MHB Medial Habenula nucleus-nucleus [Connections (S -> MHb, abstract)]
FEC FAM.FT.BNST FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial nucleus-nucleus (unknown reference)
FMM FAM.FT.AM.MPV FMM.FD.TH.RE Reuniens Nucleus of Thalamus nucleus-nucleus-gaba [decision-making (AMYG -> Thalamus, abstract)]
FAM.FT.SEP.BAC FMM.FT.HF.SUBP Proximal Subiculum nucleus-allocortex [mammillary nucleus and theta rhythm (SEP -> HF, abstract)]
LAC FAM.FT.AM.MEA LAC.FD.HT.PO Preoptic Nucleus nucleus-nucleus [for serotonin in moral behavior (AMY -> HYP, abstract)]
FAM.FT.AM.MPD LAC.FD.HT.PO Preoptic Nucleus nucleus-nucleus-gaba [for serotonin in moral behavior (AMY -> HYP, abstract)]
LAC.FD.HT.PV Paraventricular Nucleus nucleus-nucleus-gaba [disruption of prefrontal cortex (AM -> HT.PV, abstract)]
FAM.FT.AM.MPV LAC.FD.HT.PRM Premammillary Nucleus nucleus-nucleus-gaba [disruption of prefrontal cortex (AM -> HT.L, abstract)]
LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus nucleus-nucleus-gaba [for serotonin in moral behavior (AMY -> HYP, abstract)]
LMC FAM.FT.BNST LMC.FT.NBM Basal Nucleus of Meynert nucleus-nucleus (unknown reference)
LMC.HP.LC Locus Coeruleus nucleus-nucleus (unknown reference)
LMC.MM.VTA Ventral Tegmental Area nucleus-nucleus (unknown reference)
LPC FAM.FT.IPAC.MED LPC.HM.SOL Solitary Nucleus nucleus-nucleus (unknown reference)
LPC.HP.PB Parabrachial Nucleus nucleus-nucleus (unknown reference)

Express Fight Emotions

unavailable

Component ID Component Name Type Service Function Comments
FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus FAU mediate behavioral responses, output projections
FAM.FT.SEP.SH Septohippocampal Nucleus nucleus FAU participate in solving conflict between two or more competing goals, defensive
circuit

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NDM FAM.FT.SEP.SH NDM.NC.AL.FPC Lateral Frontopolar Cortex neocortex-nucleus (unknown reference)
Subcortical
FAM FAM.FT.AM.CEM FAM.FT.AM.AB Accessory Basal Amygdaloid Nucleus nucleus-nucleus [alarm system (AB -> CE, abstract)]
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus nucleus-nucleus [and its network (BLN -> CEA, abstract)]
FAM.FT.AM.CEC Central Amygdaloid Nucleus, capsular subdivision nucleus-nucleus (unknown reference)
FAM.FT.AM.CEL Central Amygdaloid Nucleus, lateral subdivision nucleus-nucleus (unknown reference)
FAM.FT.AM.ITC Intercalated Amygdaloid Nuclei nucleus-nucleus-gaba (unknown reference)
FAM.FT.AM.MEA Medial Anterior Amygdaloid Nucleus nucleus-nucleus [alarm system (MED -> CE, abstract)]
FEC FAM.FT.AM.CEM FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial nucleus-nucleus-DA (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FAM FAM.FT.AM.CEM FAM.FT.SEP.LT Lateral Septal Nucleus nucleus-nucleus (unknown reference)
LAC FAM.FT.AM.CEM LAC.FD.HT.LTN Lateral Hypothalamic Nucleus nucleus-nucleus [disruption of prefrontal cortex (AM -> HT.L, abstract)]
FAM.FT.SEP.SH LAC.FD.HT.LTN Lateral Hypothalamic Nucleus nucleus-nucleus [Gyrus (SEP -> HT, abstract)]
LMC FAM.FT.AM.CEM LMC.FT.NBM Basal Nucleus of Meynert nucleus-nucleus (unknown reference)
LMC.MM.PAG Periaqueductal Gray Matter nucleus-nucleus [disruption of prefrontal cortex (AM -> PAG, abstract)]

Solving Fight-Flight Dilemma

unavailable

Component ID Component Name Type Service Function Comments
FAM.FT.SEP.LT Lateral Septal Nucleus nucleus FAU promote active stress coping behavior

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Subcortical
FAM FAM.FT.SEP.LT FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.MPV Medial Posteror Ventral Amygdaloid Nucleus nucleus-nucleus-gaba (unknown reference)
LAC FAM.FT.SEP.LT LAC.FD.HT.PN Posterior Hypothalamic Nucleus nucleus-nucleus (unknown reference)
LAC.FD.HT.TBM Tuberomammillary Nucleus nucleus-nucleus (unknown reference)
LMC FAM.FT.SEP.LT LMC.MM.RF.SUC Superior Central Raphe Nucleus nucleus-nucleus-5HT (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
LAC FAM.FT.SEP.LT LAC.FD.HT.PO Preoptic Nucleus nucleus-nucleus-gaba [Gyrus (SEP -> HT, abstract)]
LPC FAM.FT.SEP.LT LPC.FD.TH.PV Paraventricular Nucleus of Thalamus nucleus-nucleus-gaba (unknown reference)

Memory Formation Affective Focus

unavailable

Component ID Component Name Type Service Function Comments
FAM.FT.SEP.DBB Diagonal Band of Broca nucleus FAU involved in generation of theta waves in hippocampus ACh and GABA; ventral group - from stria terminalis
to/from MFB
FAM.FT.SEP.MED Medial Septal Nucleus nucleus FAU affect HC for spatial learning, generation of theta waves output nucleus; projections from AM and HC overlap;
control theta rythm and exprolatory behavior;
from/to MFB to fornix fimbria

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Subcortical
FMM FAM.FT.SEP.MED FMM.FT.HC.CA1D Distal CA1 of Hippocampus allocortex-nucleus [Network in Hippocampus (CA1 -> SEP, abstract)]
LAC FAM.FT.SEP.DBB LAC.FD.HT.SUM Supramammillary Nucleus nucleus-nucleus [mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)]
FAM.FT.SEP.MED LAC.FD.HT.SUM Supramammillary Nucleus nucleus-nucleus [mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)]
LMC FAM.FT.SEP.DBB LMC.HP.LC Locus Coeruleus nucleus-nucleus-NE (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Cortical
NCP FAM.FT.SEP.MED NCP.NC.MPL.RSC Retrosplenial Cortex nucleus-neocortex-ACh [mammillary nucleus and theta rhythm (SEP -> RSP, abstract)]
NDM FAM.FT.SEP.DBB NDM.NC.AL.VMPFC Ventromedial Prefrontal Cortex nucleus-neocortex-gaba (unknown reference)
FAM.FT.SEP.MED NDM.FD.TH.MDM Medial Mediodorsal Nucleus of Thalamus nucleus-nucleus-ACh [relationships (s1MD -> MD, abstract)]
Subcortical
FEC FAM.FT.SEP.MED FEC.FD.TH.PF Parafascicular Nucleus of Thalamus nucleus-nucleus-ACh (unknown reference)
FMM FAM.FT.SEP.DBB FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus-gaba [Gyrus (SEP -> HT, abstract)]
FMM.FT.HC.CA2 Dorsolateral Cornu Ammonis of Hippocampus nucleus-allocortex-gaba [mammillary nucleus and theta rhythm (SEP -> HF, abstract)]
FAM.FT.SEP.MED FMM.FD.MB.LMB Lateral Mammillary Nucleus nucleus-nucleus-ACh [Gyrus (SEP -> HT, abstract)]
FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus-gaba [Gyrus (SEP -> HT, abstract)]

Reward Emotions Control

unavailable

Component ID Component Name Type Service Function Comments
FAM.FD.MHB Medial Habenula nucleus FAU Encoding negative feedback, indirect affects VTA, dorsal raphe but via interpeduncular
nucleus
FAM.FT.EPF Endopiriform Nucleus nucleus FAU Putative relay of limbic-associated cortical-like areas subserving affective
information
FAM.HP.NI Incertus Nucleus nucleus LUS Behavioural activation and the response to stress Modulating influences on prefrontal and hippocampal
cortical activity, midline behavior control;
modulatory nucleus; relay from reticularis pontis
oralis nucleus to septo-hippocampal system
FAM.HP.PPN.IPD Interpeduncular Nucleus nucleus FEU postural control, voluntary arm and eye movements Pars compacta, anterior, compact subnucleus, ACh;
unpaired
FAM.HP.PPN.RMTG Rostromedial Tegmental Nucleus nucleus FEU locomotion - walking, running Pars dissipata, anterior, dissipated subnucleus,
GABA

Internal Region Connections:

Source Region Target Region Type Reference
FAM.FD.MHB FAM.HP.PPN.IPD nucleus-nucleus [Connections (MHb -> IP)]
FAM.HP.NI FAM.FT.EPF nucleus-nucleus-gaba (unknown reference)
FAM.HP.PPN.RMTG FAM.HP.PPN.IPD nucleus-nucleus-gaba (unknown reference)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NSA FAM.FT.EPF NSA.NC.PH.PIR Piriform Cortex neocortex-nucleus [sensory system of rat and macaque (PiR -> EnP)]
Subcortical
FAM FAM.FD.MHB FAM.FT.SEP.BAC Bed Nucleus of Anterior Commissure nucleus-nucleus [Connections (S -> MHb, abstract)]
FAM.FT.SEP.SF Septofimbrial Nucleus nucleus-nucleus-gaba [Connections (S -> MHb, abstract)]
FAM.FT.SEP.TR Triangular Septal Nucleus nucleus-nucleus-gaba [Connections (S -> MHb, abstract)]
FAM.HP.PPN.RMTG FAM.FD.LHB.LT Lateral Habenula Lateral Part nucleus-nucleus [and its network (LHB -> RMTG, abstract)]
FEC FAM.HP.PPN.IPD FEC.FD.STN.ICD Subthalamic Nucleus Internal Caudal nucleus-nucleus (unknown reference)
FEC.FT.SNR.MED Substantia Nigra Pars Reticulata Medial nucleus-nucleus-gaba (unknown reference)
FAM.HP.PPN.RMTG FEC.FD.STN.LT Subthalamic Nucleus Lateral nucleus-nucleus (unknown reference)
LMC FAM.FD.MHB LMC.HP.LC Locus Coeruleus nucleus-nucleus-NE (unknown reference)
FAM.HP.PPN.IPD LMC.HP.TG.LDT Laterodorsal Tegmental Nucleus nucleus-nucleus-ACh [Direction Cell Circuit (DTN -> IPD)]
LRC FAM.HP.NI LRC.HP.PRF.RPO Oral Pontine Reticular Nucleus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Cortical
NCP FAM.FT.EPF NCP.NC.INS.AIC Anterior Insular Cortex nucleus-neocortex [sensory system of rat and macaque (EnP -> Iav, abstract)]
NSA FAM.HP.PPN.IPD NSA.FD.LGN Lateral Geniculate Nucleus nucleus-nucleus-ACh [and Extyrageniculate Paths (PPN -> LGN, abstract)]
Subcortical
FAM FAM.FD.MHB FAM.FD.LHB.MED Lateral Habenula Medial Part nucleus-nucleus (unknown reference)
FAM.HP.NI FAM.FD.LHB.MED Lateral Habenula Medial Part nucleus-nucleus-gaba (unknown reference)
FAM.FT.SEP.SF Septofimbrial Nucleus nucleus-nucleus-gaba (unknown reference)
FAM.FT.SEP.TR Triangular Septal Nucleus nucleus-nucleus-gaba (unknown reference)
FEC FAM.HP.PPN.IPD FEC.FD.STN.LT Subthalamic Nucleus Lateral nucleus-nucleus-ACh (unknown reference)
FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral nucleus-nucleus-ACh (unknown reference)
FMM FAM.HP.NI FMM.NC.PH.PER Perirhinal Cortex nucleus-neocortex-gaba (unknown reference)
LMC FAM.HP.PPN.RMTG LMC.HP.TG.LDT Laterodorsal Tegmental Nucleus nucleus-nucleus-gaba (unknown reference)
LRC FAM.HP.PPN.IPD LRC.MM.SC.INT Intermediate Superior Colliculus nucleus-nucleus-ACh [and Extyrageniculate Paths (PPN -> SC, abstract)]
Target
TEA FAM.FD.MHB TARGET.TEA.ENDOCRINE Endocrine Glands endocrine-pineal-gland [Connections (MHb -> PB)]

Fast Unconditional Sensory Data and Association Memory

unavailable

Component ID Component Name Type Service Function Comments
FAM.FT.AM.CEC Central Amygdaloid Nucleus, capsular subdivision nucleus FAU mediate behavioral responses, link to striatal effect gustatory, somatosensory, visual, auditory, frontal
cortex, perirhinal cortex, ET, SUB -> X ->
HT-dl/cl, CeM
FAM.FT.AM.CEL Central Amygdaloid Nucleus, lateral subdivision nucleus FAU mediate behavioral responses, link to gustatory and visceral aspects of
reinforcement
contributions of food prediction and food
presentation
FAM.FT.AM.COP Posterior Cortical Amygdaloid Nucleus nucleus FAU olfactory processing - unconditional signaling
FAM.FT.AM.LAVL Ventrolateral Amygdaloid Nucleus nucleus FAU unconditional stimulus input - visual, auditory and somatic, convergence from
thalamus
LA1; LGN, MGBm, PIL
FAM.FT.AM.LAVM Ventromedial Amygdaloid Nucleus nucleus FAU conditional and unconditional convergence to affect polymodal memory formation LA3; projects to ET

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NSA FAM.FT.AM.CEL NSA.NC.PO.PCC Precentral Cortex neocortex-nucleus (unknown reference)
FAM.FT.AM.LAVL NSA.FD.TH.SG Suprageniculate Nucleus of Thalamus nucleus-nucleus [disruption of prefrontal cortex (TH -> AM, abstract)]
Subcortical
FAM FAM.FT.AM.CEC FAM.FT.AM.LADL Dorsolateral Amygdaloid Nucleus nucleus-nucleus [and its network (LA -> CEA, abstract)]
FAM.FT.AM.LAVL FAM.FD.TH.PT Paratenial Nucleus of Thalamus nucleus-nucleus [disruption of prefrontal cortex (TH -> AM, abstract)]
LMC FAM.FT.AM.CEC LMC.MM.VTA Ventral Tegmental Area nucleus-nucleus-DA [circuit of human brain (VTA -> AM, abstract)]
LPC FAM.FT.AM.CEL LPC.HP.PB Parabrachial Nucleus nucleus-nucleus [disruption of prefrontal cortex (PB -> AM, abstract)]
FAM.FT.AM.COP LPC.FT.AOB Accessory Olfactory Bulb nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FAM FAM.FT.AM.CEC FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.CEL FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.BNST Bed Nucleus of Stria Terminalis nucleus-nucleus (unknown reference)
FAM.FT.AM.COP FAM.FT.AM.MEA Medial Anterior Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.LAVL FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus nucleus-nucleus [and its network (LA -> BLN, abstract)]
FAM.FT.AM.LAVM FAM.FT.AM.AB Accessory Basal Amygdaloid Nucleus nucleus-nucleus [alarm system (LA -> AB, abstract)]
LAC FAM.FT.AM.COP LAC.FD.HT.SO Supraoptic Nucleus nucleus-nucleus [for serotonin in moral behavior (AMY -> HYP, abstract)]
LPC FAM.FT.AM.CEL LPC.HM.SOL Solitary Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.LAVM LPC.FD.TH.PV Paraventricular Nucleus of Thalamus nucleus-nucleus [decision-making (AMYG -> Thalamus, abstract)]
LPC.MM.CIC Central Nucleus of Inferior Colliculus nucleus-nucleus [Interactions in Tectum (AM -> IC, abstract)]

Thirdparty Circuits

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References

(generated)