BrainRegionFAM FT SEP MED

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Medial Septal Nucleus

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This page covers biological details of component Medial Septal Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Septal Nuclei (FAM.FT.SEP) -> Dorsal Septal Nucleus (FAM.FT.SEP.DS) -> Medial Septal Group (FAM.FT.SEP.MG) -> Medial Septal Nucleus (FAM.FT.SEP.MED) (see Mind Maps)
  • Type: nucleus
  • Brain area: Forebrain - Affective Motivations Area
  • Role: relay
  • Function: affect HC for spatial learning, generation of theta waves
  • Notes to function: output nucleus; projections from AM and HC overlap; control theta rythm and exprolatory behavior; from/to MFB to fornix fimbria

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Components

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Connectivity

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FAM.FT.SEP.MED.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
LAC LAC.FD.HT.SUM Supramammillary Nucleus excitatory-glu Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FD.MHB Medial Habenula modulatory-ach Both LHb and MHb control the dopaminergic and serotonergic systems (MS -> MHb)
FEC FEC.FD.TH.PF Parafascicular Nucleus of Thalamus modulatory-ach (unknown reference)
FMM FMM.FD.MB.LMB Lateral Mammillary Nucleus modulatory-ach Cingulate Gyrus (SEP -> HT, abstract)
FMM.FD.MB.MMB Medial Mammillary Nucleus inhibitory-gaba Cingulate Gyrus (SEP -> HT, abstract)
NCP NCP.NC.MPL.RSC Retrosplenial Cortex modulatory-ach Medial mammillary nucleus and theta rhythm (SEP -> RSP, abstract)
NDM NDM.FD.TH.MDM Medial Mediodorsal Nucleus of Thalamus modulatory-ach Thalamocortical relationships (s1MD -> MD, abstract)

Thirdparty Circuits

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References

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