BrainRegionFEC FT GPI DS

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Globus Pallidus Internal Dorsal

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This page covers biological details of component Globus Pallidus Internal Dorsal. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Globus Pallidus (FEC.FT.GP) -> Dorsal Pallidum (FEC.FT.DP) -> Globus Pallidus Internal (FEC.FT.GPI) -> Globus Pallidus Internal Dorsal (FEC.FT.GPI.DS) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Forebrain - Execution Control Area (FEC)
  • Area circuit: Executive/Cognitive Loop (FECEXE)
  • Role: basal.ganglia.suppress
  • Function: Executive loop
  • Notes to function:
    • output nucleus for caudate nucleus

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Components

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  • no child items defined

Connectivity

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FEC.FT.GPI.DS.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FEC FEC.FD.STN.CD Subthalamic Nucleus Caudal excitatory-glu uncertain Basal Ganglia Activity (STN -> GPi, abstract)
FEC.FT.CN.HD Caudate Nucleus Head inhibitory-gaba uncertain Habenula Connections (CPu -> GPi, abstract)
FEC.FT.GPE.DS Globus Pallidus External Dorsal inhibitory-gaba uncertain (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FAM FAM.FD.LHB.LT Lateral Habenula Lateral Part inhibitory-gaba uncertain Habenula Connections (GPi -> LHb, abstract)
FEC FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral inhibitory-gaba uncertain Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)
NMA NMA.FD.TH.VA Ventral Anterior Nucleus inhibitory-gaba uncertain Thalamocortical relationships (sVA -> VA, abstract)

Thirdparty Circuits

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CN.PU=Striatum,FEC.FT.ST (see Basal Ganglia)
CR=Cerebellar Complex,LLC.HT.CRC
GP=Globus Pallidus,FEC.FT.GP (see Basal Ganglia)
LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
MC=Motor Cortex,NMA.NC.MC
PMC=Premotor Cortex,NC.PMC
PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei)
SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia)
TH=Ventral Thalamus,FD.TH.VTH (see Motor Thalamus)

A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MGN=Medial Geniculate Body,NSA.FD.TH.MGB
P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus)
VA=Ventral Anterior Nucleus,NMA.FD.TH.VA
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia)
pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
pLGN=Primary Visual Cortex,NSA.NC.OCC.V1
pLP=Superior Parietal Lobule,NC.SPL
pMD=Prefrontal Cortex,NC.AL.PFC
pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1
pP=Insular Cortex,NC.INS
pVA=Supplementary Motor Cortex,NMA.NC.SMC
pVL=Motor Cortex,NMA.NC.MC
pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1
pVPM=Precentral Cortex,NCP.NC.PO.PCC
s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
s1MD=Septal Nuclei,FAM.FT.SEP
s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV
s1VL=Dentate Nucleus,LLC.HT.CR.DN
s2A=Mammillary Body,FD.MB (see Hypothalamus)
s2MD=Piriform Cortex,NSA.NC.PH.PIR
s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR
s2VL=Basal Ganglia,FEC.FT.BG
s3MD=Prefrontal Cortex,NC.AL.PFC
sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
sLD=Superior Parietal Lobule,NC.SPL
sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
sVA=Basal Ganglia,FEC.FT.BG
sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn)
sVPM=Solitary Nucleus,LPC.HL.SOL

CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
IP=Interpeduncular Nucleus,FEC.HT.TG.IPD
LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
LHb=Lateral Habenula,FAM.FD.LHB (see Habenula)
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
MHb=Medial Habenula,FAM.FD.MHB
MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC
PB=Endocrine Glands,TARGET.TEA.ENDOCRINE
S=Septal Nuclei,FAM.FT.SEP
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
VTA=Ventral Tegmental Area,LMC.MM.VTA


References

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