Difference between revisions of "BrainRegionLMC MM PAG"
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Revision as of 00:06, 18 June 2015
Periaqueductal Gray Matter
@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_MM_PAG
This page covers biological details of component Periaqueductal Gray Matter. Region is part of aHuman target integrated biological model.
- Top-down path to region: Midbrain Mesencephalon -> Periaqueductal Gray Matter (LMC.MM.PAG) (see Mind Maps)
- Type: nucleus
- Brain area: Lower Brain - Modulatory Contol Area
- Role: relay
- Function: Descending modulation of pain and in defensive behaviour
- Notes to function: if there is a lesion in the PAG, then consciousness is lost; electrical stimulation of the PAG results in immediate and profound analgesia; modulatory nucleus
(generated)
Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | excitatory-glu | Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract) |
| LAC | LAC.FD.HT.VM | Ventromedial Hypothalamic Nucleus | excitatory-glu | (unknown reference) |
| NCP | NCP.NC.AL.SGCG | Subgenual Cingulate Cortex | excitatory-glu | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| LAC | LAC.HP.BR | Barrington's Nucleus | modulatory-enk | Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR) |
| LLC | LLC.FD.TH.SF | Subfascicular Nucleus of Thalamus | modulatory-enk | (unknown reference) |
| LMC | LMC.HM.RP.MG | Raphe Magnus Nucleus | modulatory-enk | (unknown reference) |
| LMC.HM.RP.PL | Raphe Pallidus Nucleus | modulatory-enk | (unknown reference) | |
| LPC | LPC.FD.TH.PV | Paraventricular Nucleus of Thalamus | modulatory-enk | (unknown reference) |
| LPC.HM.AMB | Ambiguus Nucleus | modulatory-enk | (unknown reference) | |
| LRC | LRC.HM.RA | Retroambigualis Nucleus | modulatory-enk | (unknown reference) |
| LRC.HP.PN.SC | Nucleus Subceruleus | modulatory-enk | (unknown reference) |
Thirdparty Circuits
(generated)
- Pain matrix - see Reference
References
(generated)
- http://jp.physoc.org/content/557/1/287/F9.expansion.html
- http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0
- http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
- http://neuropolitics.org/defaultmay10.asp
