Difference between revisions of "BrainRegionLMC MM PAG"

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| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)]
 
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)]
 
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| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_PPN_IPD|FEC.HT.PPN.IPD]] || Interpeduncular Nucleus || modulatory-ach || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (IPN -> PAG)]
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| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (IPN -> PAG)]
 
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| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || [http://www.jneurosci.org/content/20/4/1589/F9.expansion Spine induction on short primary dendrites in the ventrolateral VMH (VMH -> PAG)]
 
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || [http://www.jneurosci.org/content/20/4/1589/F9.expansion Spine induction on short primary dendrites in the ventrolateral VMH (VMH -> PAG)]

Revision as of 09:28, 31 December 2015

Periaqueductal Gray Matter

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_MM_PAG


This page covers biological details of component Periaqueductal Gray Matter. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Midbrain Mesencephalon -> Periaqueductal Gray Matter (LMC.MM.PAG) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Modulatory Contol Area
  • Role: processor.autonomic
  • Function: Descending modulation of pain and in defensive behaviour
  • Notes to function: if there is a lesion in the PAG, then consciousness is lost; electrical stimulation of the PAG results in immediate and profound analgesia; modulatory nucleus

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Components

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Connectivity

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LMC.MM.PAG.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus excitatory-glu Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)
FEC FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ach Connectivity map of the habenula (IPN -> PAG)
LAC LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus excitatory-glu Spine induction on short primary dendrites in the ventrolateral VMH (VMH -> PAG)
NCP NCP.NC.AL.SGCG Subgenual Cingulate Cortex excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
LAC LAC.HT.BR Barrington's Nucleus modulatory-enk Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)
LLC LLC.FD.TH.SF Subfascicular Nucleus of Thalamus modulatory-enk (unknown reference)
LMC LMC.HL.RP.MG Raphe Magnus Nucleus modulatory-enk Connectivity map of the habenula (PAG -> Raphe, abstract)
LMC.HL.RP.PL Raphe Pallidus Nucleus modulatory-enk Connectivity map of the habenula (PAG -> Raphe, abstract)
LPC LPC.FD.TH.PV Paraventricular Nucleus of Thalamus modulatory-enk (unknown reference)
LPC.HL.AMB Ambiguus Nucleus modulatory-enk (unknown reference)
LRC LRC.HL.RA Retroambigualis Nucleus modulatory-enk (unknown reference)
LRC.HT.NSC Nucleus Subceruleus modulatory-enk (unknown reference)

Thirdparty Circuits

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References

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