Difference between revisions of "BrainRegionLMC MM PAG"

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<pre style="color: green">Periaqueductal Gray Matter
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<pre style="color: green">Periaqueductal Gray Matter</pre>
</pre>
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@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_MM_PAG]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_MM_PAG]]
 
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Region is part of aHuman target integrated biological model.
 
Region is part of aHuman target integrated biological model.
  
* *Top-down path to region*: Midbrain Mesencephalon -> Periaqueductal Gray Matter (LMC.MM.PAG) (see [[OverallMindMaps|Mind Maps]])
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* '''Top-down path to region''': Midbrain Mesencephalon -> Periaqueductal Gray Matter (LMC.MM.PAG) (see [[OverallMindMaps|Mind Maps]])
* *Type*: nucleus
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* '''Type''': nucleus
* *Brain area*: [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]]
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* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]]
* *Role*: relay
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* '''Role''': relay
* *Function*: Descending modulation of pain and in defensive behaviour
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* '''Function''': Descending modulation of pain and in defensive behaviour
* *Notes to function*: if there is a lesion in the PAG, then consciousness is lost; electrical stimulation of the PAG results in immediate and profound analgesia; modulatory nucleus
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* '''Notes to function''': if there is a lesion in the PAG, then consciousness is lost; electrical stimulation of the PAG results in immediate and profound analgesia; modulatory nucleus
 
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= Components =
 
= Components =
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*Inbound Region Connections:*
 
*Inbound Region Connections:*
  
|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* ||
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|| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' ||
|| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [[http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)]] ||
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|| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [[http://neuropolitics.org/defaultmay10.asp|Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)]] ||
|| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference) ||
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|| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference) ||
|| [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_AL_SGCG NCP.NC.AL.SGCG]] || Subgenual Cingulate Cortex || excitatory-glu || (unknown reference) ||
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|| [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_AL_SGCG|NCP.NC.AL.SGCG]] || Subgenual Cingulate Cortex || excitatory-glu || (unknown reference) ||
  
 
*Outbound Region Connections:*
 
*Outbound Region Connections:*
  
|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* ||
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|| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' ||
|| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HP_BR LAC.HP.BR]] || Barrington's Nucleus || modulatory-enk || [[http://jp.physoc.org/content/557/1/287/F9.expansion.html Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)]] ||
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|| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HP_BR|LAC.HP.BR]] || Barrington's Nucleus || modulatory-enk || [[http://jp.physoc.org/content/557/1/287/F9.expansion.html|Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)]] ||
|| [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_FD_TH_SF LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || modulatory-enk || (unknown reference) ||
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|| [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_FD_TH_SF|LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || modulatory-enk || (unknown reference) ||
|| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HM_RP_MG LMC.HM.RP.MG]] || Raphe Magnus Nucleus || modulatory-enk || (unknown reference) ||
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|| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]] || Raphe Magnus Nucleus || modulatory-enk || (unknown reference) ||
 
||  || [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]] || Raphe Pallidus Nucleus || modulatory-enk || (unknown reference) ||
 
||  || [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]] || Raphe Pallidus Nucleus || modulatory-enk || (unknown reference) ||
|| [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || modulatory-enk || (unknown reference) ||
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|| [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_FD_TH_PV|LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || modulatory-enk || (unknown reference) ||
 
||  || [[BrainRegionLPC_HM_AMB|LPC.HM.AMB]] || Ambiguus Nucleus || modulatory-enk || (unknown reference) ||
 
||  || [[BrainRegionLPC_HM_AMB|LPC.HM.AMB]] || Ambiguus Nucleus || modulatory-enk || (unknown reference) ||
|| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HM_RA LRC.HM.RA]] || Retroambigualis Nucleus || modulatory-enk || (unknown reference) ||
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|| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HM_RA|LRC.HM.RA]] || Retroambigualis Nucleus || modulatory-enk || (unknown reference) ||
 
||  || [[BrainRegionLRC_HP_PN_SC|LRC.HP.PN.SC]] || Nucleus Subceruleus || modulatory-enk || (unknown reference) ||
 
||  || [[BrainRegionLRC_HP_PN_SC|LRC.HP.PN.SC]] || Nucleus Subceruleus || modulatory-enk || (unknown reference) ||
  
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* [[http://jp.physoc.org/content/557/1/287/F9.large.jpg|Schematic overview of spinobulbospinal micturition reflex pathway]] - see [[http://jp.physoc.org/content/557/1/287/F9.expansion.html Reference]]
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* [[http://jp.physoc.org/content/557/1/287/F9.large.jpg|Schematic overview of spinobulbospinal micturition reflex pathway]] - see [[http://jp.physoc.org/content/557/1/287/F9.expansion.html|Reference]]
  
 
<img src="http://jp.physoc.org/content/557/1/287/F9.large.jpg" alt="unavailable">
 
<img src="http://jp.physoc.org/content/557/1/287/F9.large.jpg" alt="unavailable">
  
* [[http://www.springerimages.com/img/Images/Springer/JOU=10194/VOL=2006.7/ISU=4/ART=2006_307/MediaObjects/MEDIUM_10194_2006_Article_307_Fig1.jpg|Pain matrix]] - see [[http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0 Reference]]
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* [[http://www.springerimages.com/img/Images/Springer/JOU=10194/VOL=2006.7/ISU=4/ART=2006_307/MediaObjects/MEDIUM_10194_2006_Article_307_Fig1.jpg|Pain matrix]] - see [[http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0|Reference]]
  
 
<img src="http://www.springerimages.com/img/Images/Springer/JOU=10194/VOL=2006.7/ISU=4/ART=2006_307/MediaObjects/MEDIUM_10194_2006_Article_307_Fig1.jpg" alt="unavailable">
 
<img src="http://www.springerimages.com/img/Images/Springer/JOU=10194/VOL=2006.7/ISU=4/ART=2006_307/MediaObjects/MEDIUM_10194_2006_Article_307_Fig1.jpg" alt="unavailable">
  
* [[http://www.surgicalneurologyint.com/articles/2012/3/2/images/SurgNeurolInt_2012_3_2_40_91609_u1.jpg|Amygdala and its network]] - see [[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Reference]]
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* [[http://www.surgicalneurologyint.com/articles/2012/3/2/images/SurgNeurolInt_2012_3_2_40_91609_u1.jpg|Amygdala and its network]] - see [[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin|Reference]]
  
 
<img src="http://www.surgicalneurologyint.com/articles/2012/3/2/images/SurgNeurolInt_2012_3_2_40_91609_u1.jpg" alt="unavailable">
 
<img src="http://www.surgicalneurologyint.com/articles/2012/3/2/images/SurgNeurolInt_2012_3_2_40_91609_u1.jpg" alt="unavailable">
  
* [[http://neuropolitics.org/connect-amygdala.jpg|Amygdalar disruption of prefrontal cortex]] - see [[http://neuropolitics.org/defaultmay10.asp Reference]]
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* [[http://neuropolitics.org/connect-amygdala.jpg|Amygdalar disruption of prefrontal cortex]] - see [[http://neuropolitics.org/defaultmay10.asp|Reference]]
  
 
<img src="http://neuropolitics.org/connect-amygdala.jpg" alt="unavailable">
 
<img src="http://neuropolitics.org/connect-amygdala.jpg" alt="unavailable">

Revision as of 10:43, 16 June 2015

Periaqueductal Gray Matter

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_MM_PAG


This page covers biological details of component Periaqueductal Gray Matter. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Midbrain Mesencephalon -> Periaqueductal Gray Matter (LMC.MM.PAG) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Modulatory Contol Area
  • Role: relay
  • Function: Descending modulation of pain and in defensive behaviour
  • Notes to function: if there is a lesion in the PAG, then consciousness is lost; electrical stimulation of the PAG results in immediate and profound analgesia; modulatory nucleus

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Components

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Connectivity

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LMC.MM.PAG.dot.png

  • Inbound Region Connections:*

|| Source Area || Source Region || Source Name || Type || Reference || || FAM || FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || excitatory-glu || [disruption of prefrontal cortex (AM -> PAG, abstract)] || || LAC || LAC.FD.HT.VM || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference) || || NCP || NCP.NC.AL.SGCG || Subgenual Cingulate Cortex || excitatory-glu || (unknown reference) ||

  • Outbound Region Connections:*

|| Target Area || Target Region || Target Name || Type || Reference || || LAC || LAC.HP.BR || Barrington's Nucleus || modulatory-enk || [overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)] || || LLC || LLC.FD.TH.SF || Subfascicular Nucleus of Thalamus || modulatory-enk || (unknown reference) || || LMC || LMC.HM.RP.MG || Raphe Magnus Nucleus || modulatory-enk || (unknown reference) || || || LMC.HM.RP.PL || Raphe Pallidus Nucleus || modulatory-enk || (unknown reference) || || LPC || LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || modulatory-enk || (unknown reference) || || || LPC.HM.AMB || Ambiguus Nucleus || modulatory-enk || (unknown reference) || || LRC || LRC.HM.RA || Retroambigualis Nucleus || modulatory-enk || (unknown reference) || || || LRC.HP.PN.SC || Nucleus Subceruleus || modulatory-enk || (unknown reference) ||

Thirdparty Circuits

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References

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