BrainRegionNCP NC INS PIC
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Posterior Insular Cortex
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This page covers biological details of component Posterior Insular Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Insular Cortex (NC.INS) -> Posterior Insular Cortex (NCP.NC.INS.PIC) (see Mind Maps)
- Type: cortex
- Brain area: Neocortical Brain - Conscious Personality Area
- Brodmann ID: 13
- Role: cortex.sensory.primary
- Function: Awareness and sensation of pain
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| LPC | LPC.HT.PRF.PB | Parabrachial Nucleus | excitatory-glu | Gustatory sensory system of rat and macaque (PB -> Gud, abstract) |
| NCP | NCP.FD.TH.VPI | Ventral Posteroinferior Nucleus | excitatory-glu | Pain matrix (TH.VPI -> INS) |
| NCP.FD.TH.VPM | Ventral Posteromedial Nucleus | excitatory-glu | Amygdalar disruption of prefrontal cortex (TH -> INS, abstract) | |
| NCP.NC.SPL.SA | Somatosensory Association Cortex | feedforward-glu | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FAM | FAM.FT.AM.BM | Magnocellular Basal Amygdaloid Nucleus | excitatory-glu | Afferent pain pathways (Insula -> AMY, abstract) |
| NCP | NCP.NC.INS.AIC | Anterior Insular Cortex | feedforward-glu | Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract) |
| NCP.NC.INS.PPC | Peripaleocortical Claustral | feedforward-glu | Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract) |
Thirdparty Circuits
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- Gustatory sensory system of rat and macaque - see Reference (CP.GUSTATORY-OLFACTORY)
EnP=Endopiriform Nucleus,FAM.FT.EPF Gud=Insular Cortex,NC.INS Gug=Insular Cortex,NC.INS HF=Hippocampal Formation,FMM.FT.HF IadIap=Insular Cortex,NC.INS Iav=Insular Cortex,NC.INS NST=Solitary Nucleus,LPC.HL.SOL PB=Parabrachial Nucleus,LPC.HT.PRF.PB PiR=Piriform Cortex,NSA.NC.PH.PIR PrC=Perirhinal Cortex,FMM.NC.PH.PER VPMpc=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
- Afferent pain pathways - see Reference (CF.PAIN-PATH)
ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AMY=Amygdala,FAM.FT.AM BG=Basal Ganglia,FEC.FT.BG Cerebellum=Cerebellar Complex,LLC.HT.CRC Insula=Insular Cortex,NC.INS PAG=Periaqueductal Gray Matter,LMC.MM.PAG PB=Parabrachial Nucleus,LPC.HT.PRF.PB PFC=Prefrontal Cortex,NC.AL.PFC S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2 SC=Posterior/Dorsal Horn,BMA.SC.PH Thalamus=Sensory Thalamus,FD.TH.SR
- Pain matrix - see Reference (CF.SOMATOSENSORY-THALAMUS)
INS=Posterior Insular Cortex,NCP.NC.INS.PIC S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 TH.VPI=Ventral Posteroinferior Nucleus,NCP.FD.TH.VPI TH.VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL TH.VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
References
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