View source for BrainRegionFMM FT HC CA2


<pre style="color: green">Dorsolateral Cornu Ammonis of Hippocampus</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFMM]] -> [[BrainRegionFMM_FT_HC_CA2]]
----

This page covers biological details of component Dorsolateral Cornu Ammonis of Hippocampus.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFMM_FT_HF|Hippocampal Formation]] (FMM.FT.HF) -> Hippocampus (FMM.FT.HC) -> [[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus]] (FMM.FT.HC.CA2) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': cortex
* '''Brain area''': [[BrainAreaFMM|Forebrain - Memory Management Area]]
* '''Role''': processor.memory.ca2
* '''Function''': Gate controlled by the activity of the supramammillary nucleus to control signal propagation between HC lamines
* '''Notes to function''': Hippocampus. Receives theta rithm input from Septum Nucleus; the only SUM projection in rat, the only converge from ET L2 and L3; social memory
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/FMM.FT.HC.CA2.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_SEP_DBB|FAM.FT.SEP.DBB]] || Diagonal Band of Broca || inhibitory-gaba || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)]
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HC_CA3D|FMM.FT.HC.CA3D]] || Distal CA3 of Hippocampus || inhibitory-gaba || [http://www.sciencedirect.com/science/article/pii/S1571064507000243 KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA3M|FMM.FT.HC.CA3M]] || Middle CA3 of Hippocampus || inhibitory-gaba || [http://www.sciencedirect.com/science/article/pii/S1571064507000243 KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA3P|FMM.FT.HC.CA3P]] || Proximal CA3 of Hippocampus || inhibitory-gaba || [http://www.sciencedirect.com/science/article/pii/S1571064507000243 KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]
|-
|  || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (EC -> HC, abstract)]
|-
|  || [[BrainRegionFMM_NC_PH_MEC|FMM.NC.PH.MEC]] || Medial Entorhinal Cortex || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (EC -> HC, abstract)]
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_SUM|LAC.FD.HT.SUM]] || Supramammillary Nucleus || excitatory-glu || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)]
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HC_CA1D|FMM.FT.HC.CA1D]] || Distal CA1 of Hippocampus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA1M|FMM.FT.HC.CA1M]] || Middle CA1 of Hippocampus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA1P|FMM.FT.HC.CA1P]] || Proximal CA1 of Hippocampus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)]
|}

= Thirdparty Circuits =
(generated)

* [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference]

map: AD=[[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus,FMM.FD.TH.AD]], DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]], EC=Entorhinal Cortex,FMM.NC.PH.ET ([[BrainRegionFMM_NC_PH_LEC|Lateral Entorhinal Cortex]] (FMM.NC.PH.LEC), [[BrainRegionFMM_NC_PH_MEC|Medial Entorhinal Cortex]] (FMM.NC.PH.MEC)), HC=Hippocampus,FMM.FT.HC ([[BrainRegionFMM_FT_HC_DG|Dentate Gyrus]] (FMM.FT.HC.DG), [[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D), [[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus]] (FMM.FT.HC.CA2), [[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), IPD=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]], LD=[[BrainRegionFMM_FD_TH_LD|Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]], LHAB=[[BrainCenter|Habenula,FAM.FD.HB]], LMB=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]], MVSN=[[BrainRegionLPC_HT_MVBN|Medial Vestibular Nucleus,LPC.HT.MVBN]], NPRP=[[BrainRegionLRC_HL_NPH|Prepositus Nucleus,LRC.HL.NPH]], PC=Parietal Lobe,NC.LOBE.PAR ([[BrainRegionNPE_NC_IPL_MST|Medial Superior Temporal Area]] (NPE.NC.IPL.MST), [[BrainRegionNPE_NC_IPL_SMW|Supramarginal Wernike Cortex]] (NPE.NC.IPL.SMW), [[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex]] (NCP.NC.MPL.RSC), [[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex]] (NCP.NC.MPL.PSCG), [[BrainRegionNCP_NC_MPL_SGCG|Subgenual Cingulate Cortex]] (NCP.NC.MPL.SGCG), [[BrainRegionNCP_NC_PO_PCC|Precentral Cortex]] (NCP.NC.PO.PCC), [[BrainRegionNCP_NC_PG_S1|Primary Somatosensory Cortex]] (NCP.NC.PG.S1), [[BrainRegionNCP_NC_PG_S2|Secondary Somatosensory Cortex]] (NCP.NC.PG.S2), [[BrainRegionNCP_NC_PG_PV|Parietal Ventral Cortex]] (NCP.NC.PG.PV), [[BrainRegionNCP_NC_SPL_SA|Somatosensory Association Cortex]] (NCP.NC.SPL.SA), [[BrainRegionNPE_NC_SPL_PF|Rostral Precuneus]] (NPE.NC.SPL.PF), [[BrainRegionNPE_NC_SPL_PG|Caudal Precuneus]] (NPE.NC.SPL.PG), [[BrainRegionNPE_NC_IPS_MIP|Medial Intraparietal Sulcus]] (NPE.NC.IPS.MIP), [[BrainRegionNPE_NC_IPS_LIP|Lateral Intraparietal Sulcus]] (NPE.NC.IPS.LIP), [[BrainRegionNSA_NC_IPS_VIP|Ventral Intraparietal Sulcus]] (NSA.NC.IPS.VIP), [[BrainRegionNSA_NC_IPS_AIP|Anterior Intraparietal Sulcus]] (NSA.NC.IPS.AIP)), PRHC=[[BrainRegionFMM_NC_PH_POR|Postrhinal Cortex,FMM.NC.PH.POR]], PSUB=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]], RSP=[[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex,NCP.NC.MPL.RSC]], SUPGEN=[[BrainRegionNSA_FD_TH_SG|Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG]], VC=[[BrainCenter|Occipital Lobe,NC.LOBE.OCC]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/1f4c1812ddb8ec93b53b4ed26dc3a381.png" alt="unavailable" style="max-width: 100%;">

* [http://ars.els-cdn.com/content/image/1-s2.0-S030645220600755X-gr1.jpg Flow of impulses in hippocampal region] - see [http://www.sciencedirect.com/science/article/pii/S030645220600755X Reference]

map: CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 ([[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D)), CA2=[[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA2]], CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 ([[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]], ENT=Entorhinal Cortex,FMM.NC.PH.ET ([[BrainRegionFMM_NC_PH_LEC|Lateral Entorhinal Cortex]] (FMM.NC.PH.LEC), [[BrainRegionFMM_NC_PH_MEC|Medial Entorhinal Cortex]] (FMM.NC.PH.MEC)), PRES=[[BrainRegionFMM_NC_PH_PRS|Presubiculum,FMM.NC.PH.PRS]], SUB=Subiculum,FMM.FT.HF.SUB ([[BrainRegionFMM_FT_HF_SUBP|Proximal Subiculum]] (FMM.FT.HF.SUBP), [[BrainRegionFMM_FT_HF_SUBM|Middle Subiculum]] (FMM.FT.HF.SUBM), [[BrainRegionFMM_FT_HF_SUBD|Distal Subiculum]] (FMM.FT.HF.SUBD))
<img src="http://ahuman.org/svn/ahwiki/images/ext/580aa7b278489489ab1588bf27e90aaf.jpg" alt="unavailable" style="max-width: 100%;">

* [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference]

map: CPu=Striatum,FEC.FT.ST ([[BrainRegionFEC_FT_ACC_CORE|Nucleus Accumbens Core]] (FEC.FT.ACC.CORE), [[BrainRegionFEC_FT_ACC_SH|Nucleus Accumbens Shell]] (FEC.FT.ACC.SH), [[BrainRegionFEC_FT_PU_VT|Ventral Putamen]] (FEC.FT.PU.VT), [[BrainRegionFEC_FT_CN_HD|Caudate Nucleus Head]] (FEC.FT.CN.HD), [[BrainRegionFEC_FT_CN_BD|Caudate Nucleus Body]] (FEC.FT.CN.BD), [[BrainRegionFEC_FT_CN_TL|Caudate Nucleus Tail]] (FEC.FT.CN.TL), [[BrainRegionFEC_FT_PU_LT|Dorsal Putamen Lateral]] (FEC.FT.PU.LT), [[BrainRegionFEC_FT_PU_MED|Dorsal Putamen Medial]] (FEC.FT.PU.MED)), EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]], Hippo=Hippocampus,FMM.FT.HC ([[BrainRegionFMM_FT_HC_DG|Dentate Gyrus]] (FMM.FT.HC.DG), [[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D), [[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus]] (FMM.FT.HC.CA2), [[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]], L=Lateral Habenula,FAM.FD.LHB ([[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part]] (FAM.FD.LHB.MED), [[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part]] (FAM.FD.LHB.LT)), LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]], M=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]], NAc=Accumbens Nucleus,FEC.FT.ACC ([[BrainRegionFEC_FT_ACC_CORE|Nucleus Accumbens Core]] (FEC.FT.ACC.CORE), [[BrainRegionFEC_FT_ACC_SH|Nucleus Accumbens Shell]] (FEC.FT.ACC.SH)), PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]], Raphe=Raphe Nuclei of Medulla,LMC.HL.RP ([[BrainRegionLMC_HL_RP_PL|Raphe Pallidus Nucleus]] (LMC.HL.RP.PL), [[BrainRegionLMC_HL_RP_OB|Raphe Obscurus Nucleus]] (LMC.HL.RP.OB), [[BrainRegionLMC_HL_RP_MG|Raphe Magnus Nucleus]] (LMC.HL.RP.MG)), SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC ([[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral]] (FEC.FT.SNC.LT), [[BrainRegionFEC_FT_SNC_MED|Substantia Nigra Pars Compacta Medial]] (FEC.FT.SNC.MED)), Septum=[[BrainCenter|Septal Nuclei,FAM.FT.SEP]], VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt="unavailable" style="max-width: 100%;">

* [http://www.nature.com/nrn/journal/v5/n7/images/nrn1432-f2.jpg Feeling] - see [http://www.nature.com/nrn/journal/v5/n7 Reference]

map: AN=Anterior Nucleus of Thalamus,FD.TH.AN ([[BrainRegionNCP_FD_TH_AM|Anteromedial Nucleus]] (NCP.FD.TH.AM), [[BrainRegionFMM_FD_TH_AV|Anteroventral Nucleus]] (FMM.FD.TH.AV), [[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus]] (FMM.FD.TH.AD)), CG=[[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]], HC=Hippocampus,FMM.FT.HC ([[BrainRegionFMM_FT_HC_DG|Dentate Gyrus]] (FMM.FT.HC.DG), [[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D), [[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus]] (FMM.FT.HC.CA2), [[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), HT=[[BrainCenter|Hypothalamus,FD.HT]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/739bae9479f0b9abd97f4fa36e001aff.jpg" alt="unavailable" style="max-width: 100%;">

* [http://ars.els-cdn.com/content/image/1-s2.0-S1571064507000243-gr008.jpg KIV model of cortico-hippocampal formation with subcortical projections for motor actions] - see [http://www.sciencedirect.com/science/article/pii/S1571064507000243 Reference]

map: AON=[[BrainRegionLPC_FT_AON|Anterior Olfactory Nucleus,LPC.FT.AON]], CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 ([[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D)), CA2=[[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA2]], CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 ([[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]], EC=Entorhinal Cortex,FMM.NC.PH.ET ([[BrainRegionFMM_NC_PH_LEC|Lateral Entorhinal Cortex]] (FMM.NC.PH.LEC), [[BrainRegionFMM_NC_PH_MEC|Medial Entorhinal Cortex]] (FMM.NC.PH.MEC)), PC=[[BrainRegionNSA_NC_PH_PIR|Piriform Cortex,NSA.NC.PH.PIR]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/b8b348173e7e4f2d3566d90a1134af17.jpg" alt="unavailable" style="max-width: 100%;">

* [http://what-when-how.com/wp-content/uploads/2012/04/tmp3637_thumb.jpg Hippocampus in Detail] - see [http://what-when-how.com/neuroscience/the-limbic-system-integrative-systems-part-1/ Reference]

map: CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 ([[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D)), CA2=[[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA2]], CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 ([[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), CA4=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/5acbe42210ca201ccb49215d89789307.jpg" alt="unavailable" style="max-width: 100%;">


= References =
(generated)

* http://www.scholarpedia.org/article/Head_direction_cells
* http://www.sciencedirect.com/science/article/pii/S030645220600755X
* http://jn.physiology.org/content/107/10/2633
* http://www.nature.com/nrn/journal/v5/n7
* http://www.sciencedirect.com/science/article/pii/S1571064507000243
* http://what-when-how.com/neuroscience/the-limbic-system-integrative-systems-part-1/