View source for BrainRegionFAM FD LHB LT

<pre style="color: green">Lateral Habenula Lateral Part</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFAM]] -> [[BrainRegionFAM_FD_LHB_LT]]
----

This page covers biological details of component Lateral Habenula Lateral Part.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFAM_FD_HB|Habenula]] (FAM.FD.HB) -> Lateral Habenula (FAM.FD.LHB) -> [[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part]] (FAM.FD.LHB.LT) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': nucleus
* '''Quality''': L0
* '''Brain area''': [[BrainAreaFAM|Forebrain - Affective Motivations Area]] (FAM)
* '''Area circuit''': Acquisition of Avoidance Responses (FAMXAA)
* '''Role''': processor.affective.avoidance
* '''Function''': Encoding negative feedback, direct, Pallidal
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/FAM.FD.LHB.LT.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_EPF|FAM.FT.EPF]] || Endopiriform Nucleus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (EPN -> LHbL)]
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_CORE|FEC.FT.ACC.CORE]] || Nucleus Accumbens Core || inhibitory-gaba || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> L, abstract)]
|-
|  || [[BrainRegionFEC_FT_GPI_DS|FEC.FT.GPI.DS]] || Globus Pallidus Internal Dorsal || inhibitory-gaba || uncertain ||[http://www.scholarpedia.org/article/Habenula Habenula Connections (GPi -> LHb, abstract)]
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)]
|-
|  || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || excitatory-glu || uncertain ||[http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)]
|-
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || modulatory-ne || uncertain ||[http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)]
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]] || Rostromedial Tegmental Nucleus || excitatory-glu || uncertain || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbL -> RMTg)]
|}

= Thirdparty Circuits =
(generated)

* [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] (CF.HB-DA5HT)

 DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]]
 DRN=[[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus,LMC.MM.RP.DRN]]
 GPb=Dorsal Pallidum,FEC.FT.DP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]]
 LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 LHbL=[[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part,FAM.FD.LHB.LT]]
 LHbM=[[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part,FAM.FD.LHB.MED]]
 LPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]]
 LS=[[BrainRegionFAM_FT_SEP_LT|Lateral Septal Nucleus,FAM.FT.SEP.LT]]
 MHb=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]]
 MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]])
 MS=[[BrainRegionFAM_FT_SEP_MED|Medial Septal Nucleus,FAM.FT.SEP.MED]]
 PS=Posterior Septal Group,FAM.FT.SEP.PG (see [[BrainCenterFAM_FT_SEP|Septal Nuclei]])
 RMTg=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]]
 SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 VP=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/97cf0802ee48a418ff7f70f80ce204e1.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg Regulation of the rapid eye movement (REM) sleep by habenular projection] - see [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Reference] (CF.REM-HB)

 DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]]
 DTG=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]]
 EPN=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]]
 GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 LHT=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 LHbL=[[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part,FAM.FD.LHB.LT]]
 LHbM=[[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part,FAM.FD.LHB.MED]]
 NI=[[BrainRegionFAM_HT_TG_NI|Incertus Nucleus,FAM.HT.TG.NI]]
 RMTg=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]]
 Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]])
 SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 VTG=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTG]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/9876de47985d221848d9333bddb7bf59.jpg" alt=alt="unavailable" style="max-width: 100%;">


= References =
(generated)

* http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
* http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full