View source for BrainRegionFEC FD STN DL

<pre style="color: green">Subthalamic Nucleus Dorsolateral</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FD_STN_DL]]
----

This page covers biological details of component Subthalamic Nucleus Dorsolateral.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFEC_FD_STA|Subthalamus Area]] (FEC.FD.STA) -> Subthalamic Nucleus (FEC.FD.STN) -> [[BrainRegionFEC_FD_STN_DL|Subthalamic Nucleus Dorsolateral]] (FEC.FD.STN.DL) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': nucleus
* '''Quality''': L0
* '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] (FEC)
* '''Area circuit''': Cognitive Motivational Salience (FECAF)
* '''Role''': basal.ganglia.subthalamus
* '''Function''': Motivational loop
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/FEC.FD.STN.DL.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
|-
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_ROFCR|NDM.NC.AL.ROFCR]] || Most Rostral Orbitofrontal Cortex || excitatory-glu || uncertain ||[http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Serotonin regulation of subthalamic neurons (CTX -> STN, abstract)]
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_GPE_RM|FEC.FT.GPE.RM]] || Globus Pallidus External Rostromedial || excitatory-glu || uncertain || [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (STN -> GPe, abstract)]
|-
|  || [[BrainRegionFEC_FT_GPI_RM|FEC.FT.GPI.RM]] || Globus Pallidus Internal Rostromedial || excitatory-glu || uncertain || [http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html Basal Ganglia Activity (STN -> GPi, abstract)]
|-
|  || [[BrainRegionFEC_FT_PU_VT|FEC.FT.PU.VT]] || Ventral Putamen || excitatory-glu || uncertain || (unknown reference)
|-
|  || [[BrainRegionFEC_FT_SNR_MED|FEC.FT.SNR.MED]] || Substantia Nigra Pars Reticulata Medial || excitatory-glu || uncertain || (unknown reference)
|-
|  || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || excitatory-glu || uncertain || [http://www.neurology.org/content/70/21/1991/F2.expansion.html Functional subdivisions of the subthalamic nucleus (STN -> VP, abstract)]
|}

= Thirdparty Circuits =
(generated)

* [http://www.neurology.org/content/70/21/1991/F2.large.jpg Functional subdivisions of the subthalamic nucleus] - see [http://www.neurology.org/content/70/21/1991/F2.expansion.html Reference] (CM.STN-CONN)

 ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [[BrainCenterNC_ACG|Anterior Cingulate Area]])
 FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see [[BrainCenterNC_PMC|Premotor Cortex]])
 GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 MC=[[BrainRegionNMA_NC_MC|Motor Cortex,NMA.NC.MC]]
 SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]])
 VP=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/ced8710309da7474ec475785e9cc3d0a.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference] (CM.SN-PPN)

 GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 PPN=[[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]]
 SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/ae877872fea7af03677243fd8481c11d.png" alt=alt="unavailable" style="max-width: 100%;">

* [http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou_2b.jpg Basal Ganglia Activity] - see [http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html Reference] (CM.BASAL-GANGLIA-ACTIVITY)

 GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 GPo=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 M1=[[BrainRegionNMA_NC_MC|Motor Cortex,NMA.NC.MC]]
 PMC=[[BrainCenterNC_PMC|Premotor Cortex,NC.PMC]]
 PU=Dorsal Putamen,FEC.FT.DPU (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 S1=[[BrainRegionNCP_NC_PG_S1|Primary Somatosensory Cortex,NCP.NC.PG.S1]]
 SMC=[[BrainCenterNMA_NC_SMC|Supplementary Motor Cortex,NMA.NC.SMC]]
 SN=Substantia Nigra,FEC.FT.SN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]])
 VLo=[[BrainRegionNMA_FD_TH_VL|Ventral Lateral Nucleus,NMA.FD.TH.VL]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/787a51951a7c6888e61f26f8abdd4bd8.jpg" alt=alt="unavailable" style="max-width: 100%;">


= References =
(generated)

* http://www.neurology.org/content/70/21/1991/F2.expansion.html
* http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs
* http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html