Dorsolateral Cornu Ammonis of Hippocampus

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This page covers biological details of component Dorsolateral Cornu Ammonis of Hippocampus. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Telencephalon -> Hippocampal Formation (FMM.FT.HF) -> Hippocampus (FMM.FT.HC) -> Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2) (see Mind Maps)
Type: cortex
Brain area: Forebrain - Memory Management Area
Role: processor
Function: Gate controlled by the activity of the supramammillary nucleus to control signal propagation between HC lamines
Notes to function: Hippocampus. Receives theta rithm input from Septum Nucleus; the only SUM projection in rat, the only converge from ET L2 and L3; social memory

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Components

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Connectivity

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FMM.FT.HC.CA2.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.SEP.DBB	Diagonal Band of Broca	inhibitory-gaba	Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)
FMM	FMM.FT.HC.CA3D	Distal CA3 of Hippocampus	inhibitory-gaba	KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)
	FMM.FT.HC.CA3M	Middle CA3 of Hippocampus	inhibitory-gaba	KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)
	FMM.FT.HC.CA3P	Proximal CA3 of Hippocampus	inhibitory-gaba	KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)
	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	excitatory-glu	Amygdala and its network (EC -> HC, abstract)
	FMM.NC.PH.MEC	Medial Entorhinal Cortex	excitatory-glu	Amygdala and its network (EC -> HC, abstract)
LAC	LAC.FD.HT.SUM	Supramammillary Nucleus	excitatory-glu	Medial mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FMM	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	excitatory-glu	Flow of impulses in hippocampal region (CA2 -> CA1, abstract)
	FMM.FT.HC.CA1M	Middle CA1 of Hippocampus	excitatory-glu	Flow of impulses in hippocampal region (CA2 -> CA1, abstract)
	FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	excitatory-glu	Flow of impulses in hippocampal region (CA2 -> CA1, abstract)