CircuitConsciousMotivations

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High-Level Motivations

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This page covers components and connections of circuit High-Level Motivations. Circuit is part of aHuman target integrated biological model.

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Components

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Mind Area Component ID Component Name Type Function
AMA BFA.FT.AM Amygdala nucleus Experiencing and recognizing emotions
BFA.FT.BNST Bed Nucleus of Stria Terminalis nucleus Mediate slow longer-lasting responses that accompany sustained threats
BFA.FT.SEP Septal Nucleus nucleus Inhibition of fear and expression of pleasurable responses
ECA BGA.FT.ACC Accumbens Nucleus nucleus Activate motor functions under attention
BGA.FT.SN.PR Substantia Nigra Pars Reticulata nucleus Convey final processed signals of basal ganglia to thalamus and superior colliculus
MCA BMA.HP.PB Parabrachial Nucleus nucleus Source of short-latency nociceptive input
EPA CGA.FD.TH.LD Lateral Dorsal Nucleus of Thalamus nucleus Head direction, spatial learning
CGA.NC.DACG Dorsal Anterior Cingulate Area cortex, BA 32 Rational Thought Processes
CGA.NC.MPL.PCG Posterior Cingulate Cortex cortex, BA 23,31 Self-awareness, pain and episodic memory retrieval
CGA.NC.MPL.RSC Retrosplenial Cortex cortex, BA 26,29,30 Processing of emotionally salient stimuli
CGA.NC.PACG Pregenual Area cortex, BA 33 Sensation of Emotion
CGA.NC.SGC Subgenual Cortex cortex, BA 25 Influences changes in appetite and sleep
CGA.NC.SPL.PF Rostral Precuneus cortex, BA 07 Spatial orientation, representation of the self
CGA.NC.VACG Ventral Anterior Cingulate Area cortex, BA 24 Seat of Free Will
MCA FBA.MM.PAG Periaqueductal Gray Matter nucleus Descending modulation of pain and in defensive behaviour
FBA.MM.VTA Ventral Tegmental Area nucleus Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues
EPA FCA.FD.TH.MD Mediodorsal Nucleus of Thalamus nucleus Attention, planning, organization, abstract thinking, multi-tasking, and active memory
FCA.NC.LPFC Dorsolateral Prefrontal Cortex cortex, BA 09,46 Temporal Integration
FCA.NC.OMPFC Orbitomedial Prefrontal Cortex cortex, BA 10,11,12 Personality
ACA HTA.FD.HT.AH Anterior Hypothalamic Nucleus nucleus Thermoregulation, panting, sweating
HTA.FD.HT.RCH Retrochiasmatic Area nucleus Maintenance of normal hypothalamic-pituitary-adrenal function
BAA SMA.NC.SPL.SA Somatosensory Association Cortex cortex, BA 05 Locating objects in space

Connections

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CircuitConsciousMotivations.dot.jpg

Source Region Target Region Type Reference
BFA.FT.AM CGA.NC.PACG nucleus-neocortex Amygdalar disruption of prefrontal cortex (AM -> ACG, abstract)
CGA.NC.VACG nucleus-neocortex Directed Effort Network (AM -> vACC)
FCA.FD.TH.MD nucleus-nucleus Prefrontal Cortex (PFC) in emotional behavior (AM -> TH)
FCA.NC.OMPFC nucleus-neocortex Amygdalar disruption of prefrontal cortex (AM -> MPFC)
BFA.FT.SEP CGA.NC.SGC nucleus-neocortex (unknown reference)
CGA.FD.TH.LD CGA.NC.SPL.PF nucleus-neocortex (unknown reference)
CGA.NC.DACG CGA.NC.VACG neocortex-neocortex Principal Connections of Hippocampus (DorsalCingulate -> VentralCingulate)
CGA.NC.MPL.RSC FCA.NC.LPFC neocortex-neocortex Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract)
FCA.NC.OMPFC neocortex-neocortex Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract)
CGA.NC.SGC BFA.FT.BNST neocortex-nucleus (unknown reference)
BMA.HP.PB neocortex-nucleus (unknown reference)
FBA.MM.PAG neocortex-nucleus (unknown reference)
HTA.FD.HT.AH neocortex-nucleus (unknown reference)
CGA.NC.SPL.PF CGA.FD.TH.LD neocortex-nucleus Thalamocortical relationships (sLD -> LD, abstract)
CGA.NC.MPL.RSC neocortex-neocortex (unknown reference)
CGA.NC.PACG neocortex-neocortex Global visual system (ParietalCortex -> FrontalCortex, abstract)
CGA.NC.VACG CGA.NC.MPL.PCG neocortex-neocortex Principal Connections of Hippocampus (VentralCingulate -> PosteriorCingulate)
FCA.FD.TH.MD CGA.NC.PACG nucleus-neocortex Saccadic Vision (Thalamus -> FrontalCortex, abstract)
FCA.NC.OMPFC BGA.FT.ACC neocortex-nucleus Affective basal ganglia circuit (OMPFC -> NACC)
BGA.FT.SN.PR neocortex-nucleus Craving (OMPFC -> SNr)
CGA.NC.PACG neocortex-neocortex Role for serotonin in moral behavior (OMPFC -> ACG, abstract)
CGA.NC.VACG neocortex-neocortex Directed Effort Network (OPFC -> vACC)
FBA.MM.VTA neocortex-nucleus Craving (OMPFC -> VTA)
FCA.NC.LPFC neocortex-neocortex Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC)
HTA.FD.HT.RCH neocortex-nucleus Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract)
SMA.NC.SPL.SA FCA.NC.OMPFC neocortex-neocortex Cortico-Cortical Connectivity (SA -> PFC, abstract)