CircuitMuscleControl

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Muscle Control

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This page covers components and connections of circuit Muscle Control. Circuit is part of aHuman target integrated biological model.

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Components

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Mind Area Component ID Component Name Type Function
ACA AVA.HM.VG Vagus Nucleus nucleus Parasympathetic vagal functions in the gastrointestinal tract, lungs
AVA.PN.PSYM.ILG Intralaryngeal Peripheral Ganglion parasympathetic ganglion parasympathetic motor of larynx, c.n. X
AVA.PN.PSYM.PPG Pelvic Peripheral Ganglion parasympathetic ganglion Sigmoid, rectum, bladder, and external genitalia
AVA.PN.SYM.ARG Aorticorenal Ganglion sympathetic ganglion Kidney, Ureter
AVA.PN.SYM.CEG Coelic Ganglion sympathetic ganglion Liver, stomach, pancreas, small intestine
AVA.PN.SYM.IMG Inferior Mesenteric Ganglion sympathetic ganglion Bladder, rectum, reproductive organs
AVA.PN.SYM.MCG Middle Cervical Ganglion sympathetic ganglion Eye, tear and salivatory glands
AVA.PN.SYM.SCG Superior Cervical Ganglion sympathetic ganglion Eye, tear and salivatory glands
AVA.PN.SYM.SMG Superior Mesenteric Ganglion sympathetic ganglion Large intestine, rectum
AVA.SC.IZ.IML Intermediolateral Nucleus nucleus Mediate entire sympathetic innervation of body
AVA.SC.VH.ONF Onuf's Nucleus nucleus Maintenance of urination and defecation, muscular contraction during orgasm
AMA BFA.FT.NBM Basal Nucleus of Meynert nucleus Control imagination vs perception
ECA BGA.FT.GPI Globus Pallidus Internal nucleus Output nuclei of basal ganglia to neocortex
BGA.FT.PU Putamen nucleus Stimulus-response, or habit, learning
BGA.FT.SN.PC Substantia Nigra Pars Compacta nucleus Fine motor control, temporal processing
MCA BMA.HP.PB Parabrachial Nucleus nucleus Source of short-latency nociceptive input
FBA.HP.LC Locus Coeruleus nucleus Regulate the intensity of responses to salient stimuli
FBA.MM.PAG Periaqueductal Gray Matter nucleus Descending modulation of pain and in defensive behaviour
FBA.MM.VTA Ventral Tegmental Area nucleus Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues
EPA FCA.NC.LPFC Dorsolateral Prefrontal Cortex cortex, BA 09,46 Temporal Integration
FCA.NC.OMPFC Orbitomedial Prefrontal Cortex cortex, BA 10,11,12 Personality
PCA HMA.HP.PTP.PTR Principal Trigeminal Nucleus nucleus Facial Somatic Sensations
HMA.MM.MSTR Mesencephalic Trigeminal Nucleus sensory ganglion unconscious proprioception from muscle spindles; facial somatic sensations from muscles of mastication, monosynaptic masticatory reflex
ACA HTA.FD.HT.PO Preoptic Area nucleus Thermoregulation
HTA.FD.HT.PV Paraventricular Nucleus nucleus Regulate appetite and autonomic functions
MBA.HP.BR Barrington's Nucleus nucleus Supraspinal regulation of urination
LCA MBA.HP.CR Cerebellum nucleus Motor coordination
MBA.HP.PN.PBB Pontobulbar Body nucleus Control voluntary muscle activities
MAA MCA.FD.TH.VA Ventral Anterior Nucleus nucleus Relay BGA.SN, BGA.GPI, FCA.OMPFC, FCA.CG to MCA.PMC, MCA.SMC
MCA.FD.TH.VL Ventral Lateral Nucleus nucleus Relay BSA.CR to MCA.MC
MCA.NC.MC Motor Cortex cortex, BA 04 Execution of required voluntary movements
MCA.NC.PMC.F4 Ventral Caudal Premotor Cortex cortex, BA 06 Sensory guidance of movement
MCA.NC.PMC.F5 Ventral Rostral Premotor Cortex cortex, BA 06 Shaping hand during grasping
MCA.NC.SMC Supplementary Motor Cortex cortex, BA 06 Process sequences of movements and coordinate bilateral movements
MMA PHA.NC.PH.PRR Perirhinal Cortex cortex, BA 35 Associate different visual views of objects and their various nonvisual attributes
BAA SMA.FD.TH.VPL Ventral Posterolateral Nucleus nucleus Relays somatic information from body to S1
SMA.NC.PG.S1 Somatosensory Cortex cortex, BA 01,02,03 Muscle and skin receptors
SAA VCA.NC.IPS.AIP Anterior Intraparietal Sulcus cortex, BA 39 Represent shape, size, and orientation of objects to be grasped
VCA.NC.IPS.VIP Ventral Intraparietal Sulcus cortex, BA 39 Merge visual, somatosensory, auditory, and vestibular senses
VCA.NC.IT.TE Inferotemporal Cortex cortex, BA 20 Represent different views of objects

Connections

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CircuitMuscleControl.dot.jpg

Source Region Target Region Type Reference
AVA.HM.VG AVA.PN.PSYM.ILG nucleus-ganglion (unknown reference)
AVA.PN.SYM.IMG FBA.MM.PAG ganglion-nucleus Schematic overview of spinobulbospinal micturition reflex pathway (IMG -> PAG)
MBA.HP.BR ganglion-nucleus Schematic overview of spinobulbospinal micturition reflex pathway (IMG -> BAR)
AVA.SC.IZ.IML AVA.PN.PSYM.PPG nucleus-ganglion Schematic overview of spinobulbospinal micturition reflex pathway (IML -> PEL)
AVA.PN.SYM.ARG nucleus-ganglion (unknown reference)
AVA.PN.SYM.CEG nucleus-ganglion (unknown reference)
AVA.PN.SYM.MCG nucleus-ganglion (unknown reference)
AVA.PN.SYM.SCG nucleus-ganglion (unknown reference)
AVA.PN.SYM.SMG nucleus-ganglion (unknown reference)
AVA.SC.VH.ONF nucleus-nucleus Schematic overview of spinobulbospinal micturition reflex pathway (IML -> ONF)
BFA.FT.NBM FCA.NC.OMPFC nucleus-neocortex Physiology and pathophysiology of lower urinary tract (NBM -> MPFC)
BGA.FT.GPI MCA.FD.TH.VL nucleus-nucleus Basal Ganglia Activity (GPi -> VLo)
BGA.FT.PU FBA.HP.LC nucleus-nucleus Physiology and pathophysiology of lower urinary tract (PU -> LC)
BGA.FT.SN.PC MBA.HP.CR nucleus-nucleus Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)
BMA.HP.PB AVA.HM.VG nucleus-nucleus Physiology and pathophysiology of lower urinary tract (PBN -> DVM)
FBA.HP.LC AVA.SC.IZ.IML nucleus-nucleus Physiology and pathophysiology of lower urinary tract (LC -> IML)
FBA.MM.PAG MBA.HP.BR nucleus-nucleus Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)
FBA.MM.VTA HTA.FD.HT.PO nucleus-nucleus Physiology and pathophysiology of lower urinary tract (VTA -> MPOA)
HTA.FD.HT.PV nucleus-nucleus Physiology and pathophysiology of lower urinary tract (VTA -> PVN)
FCA.NC.LPFC MCA.FD.TH.VA neocortex-nucleus Prefrontal Cortex (PFC) in motor behavior (LPFC -> TH, abstract)
HMA.MM.MSTR HMA.HP.PTP.PTR ganglion-nucleus (unknown reference)
MBA.HP.BR AVA.SC.IZ.IML nucleus-nucleus Schematic overview of spinobulbospinal micturition reflex pathway (BAR -> IML)
MBA.HP.CR FCA.NC.LPFC nucleus-neocortex Prefrontal Cortex (PFC) in motor behavior (CR -> LPFC)
MCA.FD.TH.VL nucleus-nucleus Thalamocortical relationships (s1VL -> VL)
MBA.HP.PN.PBB MBA.HP.CR nucleus-nucleus Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)
MCA.FD.TH.VL MCA.NC.MC nucleus-neocortex Thalamocortical relationships (VL -> pVL)
MCA.NC.MC MBA.HP.PN.PBB neocortex-nucleus Prefrontal Cortex (PFC) in motor behavior (MC -> PN, abstract)
SMA.NC.PG.S1 neocortex-neocortex Global visual system (FrontalCortex -> ParietalCortex, abstract)
MCA.NC.PMC.F4 FCA.NC.LPFC neocortex-neocortex Cortico-Cortical Connectivity (MA -> PFC, abstract)
MCA.NC.PMC.F5 SMA.NC.PG.S1 neocortex-neocortex Primate Control of Grasping (F5 -> S2)
VCA.NC.IPS.AIP neocortex-neocortex Primate Control of Grasping (F5 -> AIP)
SMA.FD.TH.VPL SMA.NC.PG.S1 nucleus-neocortex Pain matrix (TH.VPL -> S1)
SMA.NC.PG.S1 MCA.NC.PMC.F5 neocortex-neocortex Primate Control of Grasping (S2 -> F5)
MCA.NC.SMC neocortex-neocortex Global visual system (ParietalCortex -> FrontalCortex, abstract)
PHA.NC.PH.PRR neocortex-neocortex (unknown reference)
VCA.NC.IPS.AIP MCA.NC.PMC.F4 neocortex-neocortex Primate Control of Grasping (AIP -> F4)
MCA.NC.PMC.F5 neocortex-neocortex Primate Control of Grasping (AIP -> F5)
VCA.NC.IPS.VIP MCA.NC.PMC.F4 neocortex-neocortex Primate Control of Grasping (VIP -> F4)
VCA.NC.IT.TE VCA.NC.IPS.AIP neocortex-neocortex Primate Control of Grasping (IT -> AIP, abstract)