BiologicalArchitectureModulation

Biological Life Research

This page covers biological principles of non-specific modulation.

Overview

mind contains components which affect large mind areas at once
- these components are affected by quite specific circuits and change the mode in which brain is operating
- components are utilizing specific neurotransmitters - DA, 5HT, ACh, NE for its efferent connections
- non-specific modulators allow the mind to work as a single unit, by means of coordinating internal parts
sample behavior of modulators:
- DA circuit to speed up execution: habenula -> SNc -> striatum (D1+,D2-) -> ventroanterior thalamus (reduce inhibition) -> M1 (increased activity) -> motoneuron
- 5HT circuit to go asleep: habenula -> dorsal raphe nucleus -> paraventricular thalamus -> hypothalamus -> body
- ACh circuit to control perception vs imaginaton: amygdala -> basal nucleus of Meynert -> prefrontal cortex (-feedforward,+feedback)
- NE circuit to adopt to pain: spinal cord substantia gelatinosa -> lateral spinal nucleus -> hypothalamus -> locus coeruleus -> spinal cord substantia gelatinosa (inhibit)