CircuitMemoryMB

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Memory Process in Mammillary Bodies

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This page covers components and connections of circuit Memory Process in Mammillary Bodies. Circuit is part of aHuman target integrated biological model.

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Components

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Mind Area Component ID Component Name Type Function
AMA BFA.FT.SEP Septal Nucleus nucleus Inhibition of fear and expression of pleasurable responses
EPA CGA.FD.TH.AN Anterior Nucleus of Thalamus nucleus Extended hippocampal system
CGA.NC.MPL.RSC Retrosplenial Cortex cortex, BA 26,29,30 Processing of emotionally salient stimuli
MCA FBA.MM.VTA Ventral Tegmental Area nucleus Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues
MMA HBA.FD.MB.MMB Medial Mammillary Nucleus nucleus Relay for impulses coming from AM and HC
HBA.FT.DG Dentate Gyrus cortex Distinguishing multiple instances of similar events
HBA.FT.HC.CA1 Ventrolateral Cornu Ammonis of Hippocampus cortex Representing sequences of episodic memory - long-term
HBA.FT.HC.CA2 Dorsolateral Cornu Ammonis of Hippocampus cortex Gate controlled by the activity of the supramammillary nucleus to control signal propagation between HC lamines
HBA.FT.HC.CA3 Dorsomedial Cornu Ammonis of Hippocampus cortex Representing sequences of episodic memory - short-term
HBA.FT.SC.SUB Subiculum cortex Spatial navigation and mnemonic processing
MRA HMA.HP.PRF.PDT Pontine Reticulotegmental Nucleus nucleus Mediate saccadic eye movements
ACA HTA.FD.HT.LT Lateral Nucleus nucleus Thirst and hunger
HTA.FD.HT.PN Posterior Nucleus nucleus Blood pressure, pupillary dilation
LCA MBA.HP.PN.RP Rostral Pontine Nucleus nucleus Part of learning, motivation, spatial memory pathway
MCA MBA.MM.TG.LDT Laterodorsal Tegmental Nucleus nucleus Modulating sustained attention or in mediating alerting responses
MMA PHA.FD.MB.LMB Lateral Mammillary Nucleus nucleus Generate theta rythm and relay to HC
PHA.NC.PAS Parasubiculum cortex, BA 49 Spatial navigation and the integration of head-directional information
PHA.NC.PH.ET Enthorhinal Cortex cortex, BA 28 Memory consolidation
PHA.NC.PRS Presubiculum cortex, BA 27 Path integration, head direction
PHA.NC.PSS Postsubiculum cortex, BA 48 Visual association

Connections

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CircuitMemoryMB.dot.jpg

Source Region Target Region Type Reference
BFA.FT.SEP CGA.NC.MPL.RSC nucleus-neocortex Medial mammillary nucleus and theta rhythm (SEP -> RSP)
HBA.FD.MB.MMB nucleus-nucleus Mammillary bodies: two memory systems in one (SEP -> MMB)
HBA.FT.HC.CA2 nucleus-allocortex Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)
PHA.FD.MB.LMB nucleus-nucleus Mammillary bodies: two memory systems in one (SEP -> LMB)
FBA.MM.VTA HBA.FD.MB.MMB nucleus-nucleus Mammillary bodies: two memory systems in one (VTN -> MMB)
HBA.FD.MB.MMB CGA.FD.TH.AN nucleus-nucleus Mammillary bodies: two memory systems in one (MMB -> AMTH)
FBA.MM.VTA nucleus-nucleus Medial mammillary nucleus and theta rhythm (MMB -> VTN)
HMA.HP.PRF.PDT nucleus-nucleus Mammillary Body (MMB -> RTG)
MBA.HP.PN.RP nucleus-nucleus (unknown reference)
HBA.FT.HC.CA1 HBA.FD.MB.MMB allocortex-nucleus Hippocampus and Septal Area (CA1 -> MB)
HBA.FT.HC.CA3 HBA.FD.MB.MMB allocortex-nucleus Principal Connections of Hippocampus (HC -> MB)
HBA.FT.SC.SUB HBA.FD.MB.MMB allocortex-nucleus Mammillary bodies: two memory systems in one (SUB -> MMB)
HTA.FD.HT.LT HBA.FD.MB.MMB nucleus-nucleus Mammillary bodies: two memory systems in one (TuberoMM -> MMB)
PHA.FD.MB.LMB nucleus-nucleus Mammillary bodies: two memory systems in one (TuberoMM -> LMB)
HTA.FD.HT.PN BFA.FT.SEP nucleus-nucleus Medial mammillary nucleus and theta rhythm (SupraMM -> SEP)
HBA.FD.MB.MMB nucleus-nucleus Mammillary bodies: two memory systems in one (SupraMM -> MMB)
HBA.FT.DG nucleus-allocortex Medial mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)
HBA.FT.HC.CA3 nucleus-allocortex Medial mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)
PHA.FD.MB.LMB nucleus-nucleus Mammillary bodies: two memory systems in one (SupraMM -> LMB)
MBA.MM.TG.LDT PHA.FD.MB.LMB nucleus-nucleus Hippocampal Formation (DTN -> LMam)
PHA.FD.MB.LMB CGA.FD.TH.AN nucleus-nucleus Head Direction Cell Circuit (LMB -> AD)
HMA.HP.PRF.PDT nucleus-nucleus Mammillary Body (LMB -> RTG)
MBA.MM.TG.LDT nucleus-nucleus Head Direction Cell Circuit (LMB -> DTN)
PHA.NC.PRS nucleus-neocortex Attractor Network in Hippocampus (MBOUT -> PRESUB)
PHA.NC.PAS PHA.FD.MB.LMB neocortex-nucleus Mammillary bodies: two memory systems in one (PAS -> LMB)
PHA.NC.PH.ET HBA.FD.MB.MMB neocortex-nucleus Mammillary bodies: two memory systems in one (MedialEC -> MMB)
PHA.NC.PRS HBA.FD.MB.MMB neocortex-nucleus Attractor Network in Hippocampus (PRESUB -> MBIN)
PHA.FD.MB.LMB neocortex-nucleus Mammillary bodies: two memory systems in one (PRS -> LMB)
PHA.NC.PSS PHA.FD.MB.LMB neocortex-nucleus Head Direction Cell Circuit (PSUB -> LMB)