View source for BrainRegionLMC HT TG LDT


<pre style="color: green">Laterodorsal Tegmental Nucleus</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_HT_TG_LDT]]
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This page covers biological details of component Laterodorsal Tegmental Nucleus.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) -> [[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus]] (LMC.HT.TG.LDT) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]]
* '''Role''': processor.autonomic
* '''Function''': Modulating sustained attention or in mediating alerting responses
* '''Notes to function''': sleep, waking, motor function, learning and reward
(generated)
= Components =
(generated)


'''Component items''':
* '''Lateral Tegmental Nucleus'''
* '''Dorsal Tegmental Nucleus''' ('''LMC.HT.TG.DTG'''): accurate landmark navigation
** '''Dorsal Tegmental Nucleus Pars Dorsalis'''
** '''Dorsal Tegmental Nucleus Pars Ventralis'''

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/LMC.HT.TG.LDT.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)]
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (IPD -> DTN)]
|-
|  || [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || (unknown reference)
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || excitatory-glu || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> DTN)]
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || excitatory-glu || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (VLPO -> LDTg)]
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || excitatory-glu || (unknown reference)
|-
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || excitatory-glu || (unknown reference)
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || (unknown reference)
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || modulatory-ach || [http://ahuman.org/svn/ahengine/research/articles/2009-Hippocampus-Thesis.pdf Hippocampal Formation (DTN -> LMam)]
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HL_SAL_ISL|LAC.HL.SAL.ISL]] || Inferior Salivatory Nucleus || modulatory-ach || (unknown reference)
|-
|  || [[BrainRegionLAC_HL_SAL_SSL|LAC.HL.SAL.SSL]] || Superior Salivatory Nucleus || modulatory-ach || (unknown reference)
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> NPRP)]
|-
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> SUPGEN)]
|}

= Thirdparty Circuits =
(generated)

* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/brain/HF.jpg Hippocampal Formation] - see [[article:2009-Hippocampus-Thesis.pdf|Reference]]

<img src="http://ahuman.org/svn/ahwiki/images/ext/4d5651d77aacaaeda0f1c20e02778bf5.jpg" alt="unavailable" style="max-width: 100%;">

* [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference]

<img src="http://ahuman.org/svn/ahwiki/images/ext/1f4c1812ddb8ec93b53b4ed26dc3a381.png" alt="unavailable" style="max-width: 100%;">

* [http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg Regulation of the rapid eye movement (REM) sleep by habenular projection] - see [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Reference]

<img src="http://ahuman.org/svn/ahwiki/images/ext/9876de47985d221848d9333bddb7bf59.jpg" alt="unavailable" style="max-width: 100%;">

* [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f2.jpg Mammillary bodies: two memory systems in one] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Reference]

<img src="http://ahuman.org/svn/ahwiki/images/ext/c973c3b2fef0f2bf256543a0a064fe81.jpg" alt="unavailable" style="max-width: 100%;">

* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference]

<img src="http://ahuman.org/svn/ahwiki/images/ext/7d1ab7f45d007c61b6a1b8abadde723d.jpg" alt="unavailable" style="max-width: 100%;">


= References =
(generated)

* article:2009-Hippocampus-Thesis.pdf
* http://www.scholarpedia.org/article/Head_direction_cells
* http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full
* http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html
* http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html