BrainRegionNCP NC PG S1

Primary Somatosensory Cortex

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This page covers biological details of component Primary Somatosensory Cortex. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Parietal Lobe (NC.LOBE.PAR) -> Postcentral Gyrus (NC.PG) -> Anterior Parietal Cortex (NC.PG.APC) -> Primary Somatosensory Cortex (NCP.NC.PG.S1) (see Mind Maps)
• Type: cortex
• Brain area: Neocortical Brain - Conscious Personality Area
• Brodmann ID: 01,02,03
• Role: cortex.sensory.primary
• Function: Muscle and skin receptors

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NCP	NCP.FD.TH.VPL	Ventral Posterolateral Nucleus	excitatory-glu	Pain matrix (TH.VPL -> S1)
	NCP.FD.TH.VPM	Ventral Posteromedial Nucleus	excitatory-glu	Pain matrix (TH.VPM -> S1)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.PU.LT	Dorsal Putamen Lateral	excitatory-glu	Basal Ganglia Activity (S1 -> PU, abstract)
LRC	LRC.HL.TGS.PA5	Paratrigeminal Nucleus	excitatory-glu	(unknown reference)
NCP	NCP.NC.PG.PV	Parietal Ventral Cortex	feedforward-glu	(unknown reference)
	NCP.NC.PG.S2	Secondary Somatosensory Cortex	feedforward-glu	Afferent pain pathways (S1 -> S2)
	NCP.NC.SPL.SA	Somatosensory Association Cortex	feedforward-glu	Cortico-Cortical Connectivity (S1 -> SA)
NMA	NMA.NC.MC	Motor Cortex	feedforward-glu	Cortico-Cortical Connectivity (S1 -> M1)
	NMA.NC.PMC.F2	Dorsal Caudal Premotor Cortex	feedforward-glu	Global visual system (ParietalCortex -> FrontalCortex, abstract)
	NMA.NC.PMC.F5	Ventral Rostral Premotor Cortex	feedforward-glu	Primate Control of Grasping (S2 -> F5)
NPE	NPE.FD.TH.OPV	Oral Pulvinar	excitatory-glu	(unknown reference)
	NPE.NC.IPL.SMW	Supramarginal Wernike Cortex	feedforward-glu	Cortico-Cortical Connectivity (S1 -> PTHA, abstract)
	NPE.NC.SPL.PG	Caudal Precuneus	feedforward-glu	McNaughton Spatial Processing Network (SomSensCortex -> PosteriorParietalCortex)

Thirdparty Circuits

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• McNaughton Spatial Processing Network - see Reference

• Global visual system - see Reference

• Primate Control of Grasping - see Reference

• Basal Ganglia Activity - see Reference

• Cortico-Cortical Connectivity - see Reference

• Afferent pain pathways - see Reference

• Somatic Senses - see Reference

• Owl Monkey Somatic Area - see Reference

• Homunculus S1 and M1 - see Reference

• Thalamocortical relationships - see Reference

• Pain matrix - see Reference

• Pain matrix - see Reference

References

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• http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html
• http://www.sciencedirect.com/science/article/pii/S0959438808001566
• http://www.sciencedirect.com/science/article/pii/S0893608098000471
• http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html
• http://www.sciencedirect.com/science/article/pii/S1053810011000080
• http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html
• http://www.biopsychology.com/6e/step0801.html
• http://www.scholarpedia.org/article/User:Tony_J._Prescott/Proposed/Primate_S1_cortex
• http://brainmind.com/BasalGanglia.html
• http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/
• http://users.atw.hu/blp6/BLP6/HTML/C0079780323045827.htm
• http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0