BrainRegionNMA NC PMC F5

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Ventral Rostral Premotor Cortex

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This page covers biological details of component Ventral Rostral Premotor Cortex. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Premotor Cortex (NC.PMC) -> Ventral Premotor Cortex (MCA.NC.VPMC) -> Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5) (see Mind Maps)
  • Type: cortex
  • Brain area: Neocortical Brain - Motor Aggregation Area
  • Brodmann ID: 06
  • Role: cortex.motor.extensor
  • Function: Shaping hand during grasping
  • Notes to function: 6VR; Mirror neurons - both sensory and motor; arm; F5c=convexity - F1/F4/F2VR/F6/F3/24d/24c, F5p=posterior - F3/F4/F1/24c/24a, F5a=anterior - F4/F6/24c/24d/24a/46v/12r/12l




  • no child items defined



Inbound Region Connections:

Source Area Source Region Source Name Type Reference
NCP NCP.NC.PG.S1 Primary Somatosensory Cortex feedforward-glu Primate Control of Grasping (S2 -> F5)
NDM NDM.NC.AL.DLPFCL Lateral Mid-Dorsolateral Prefrontal Cortex feedforward-glu Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)
NMA NMA.FD.TH.VA Ventral Anterior Nucleus excitatory-glu Primate Control of Grasping (BTH -> F5)
NMA.FD.TH.VL Ventral Lateral Nucleus excitatory-glu Basal Ganglia Activity (VLo -> PMC, abstract)
NMA.NC.SMC.F3 Supplementary Motor Area feedforward-glu 3 Visual Cortex Paths (pre-SMA -> vPM, abstract)
NMA.NC.SMC.F6 Pre-Supplementary Motor Area feedforward-glu Primate Control of Grasping (F6 -> F5)
NPE NPE.NC.PMC.AFEF Anterior Frontal Eye Field feedforward-glu Cortical Auditory System (PMC8 -> PMC6, abstract)
NPE.NC.PMC.CFEF Caudal Frontal Eye Field feedforward-glu (unknown reference)
NSA NSA.NC.IPS.AIP Anterior Intraparietal Sulcus feedforward-glu Primate Control of Grasping (AIP -> F5)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FEC FEC.FT.PU.MED Dorsal Putamen Medial excitatory-glu Primate Control of Grasping (F5 -> BG, abstract)
NMA NMA.NC.MC Motor Cortex feedforward-glu Primate Control of Grasping (F5 -> F1)
NMA.NC.PMC.F2 Dorsal Caudal Premotor Cortex feedforward-glu (unknown reference)

Thirdparty Circuits


46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
AIP=Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP
BG=Basal Ganglia,FEC.FT.BG
BTH=Ventral Anterior Nucleus,NMA.FD.TH.VA
F1=Motor Cortex,NMA.NC.MC
F2=Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2
F4=Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4
F5=Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5
F6=Pre-Supplementary Motor Area,NMA.NC.SMC.F6
IT=Inferotemporal Area,NSA.NC.IT
PIP=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus)
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Primary Somatosensory Cortex,NCP.NC.PG.S1
VC=Occipital Lobe,NC.LOBE.OCC
VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP

A1=Primary Auditory Cortex,NSA.NC.TTG.A1
AA=Wernicke's area A3,NSA.NC.STG.A3
M1=Motor Cortex,NMA.NC.MC
MA=Premotor Cortex,NC.PMC
PFC=Prefrontal Cortex,NC.AL.PFC
PTHA=Inferior Parietal Lobule,NC.IPL
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
SA=Somatosensory Association Cortex,NCP.NC.SPL.SA
V1=Primary Visual Cortex,NSA.NC.OCC.V1
VA=Secondary Visual Cortex,NSA.NC.OCC.V2 (see Occipital Lobe)