BrainRegionNMA NC SMC F6
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Pre-Supplementary Motor Area
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This page covers biological details of component Pre-Supplementary Motor Area. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Supplementary Motor Cortex (NMA.NC.SMC) -> Pre-Supplementary Motor Area (NMA.NC.SMC.F6) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Neocortical Brain - Motor Aggregation Area (NMA)
- Area circuit: Complex Motor (SEQ)
- Brodmann ID: 06
- Role: cortex.generic
- Function: High level motor functions; Numerical and verbal mental-operation tasks
- Notes to function:
- from TH/VLpc, MD from caudate, CR
- F5/24c/46
- no connections with F1
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| NDM | NDM.NC.AL.DLPFCR | Rostral Mid-Dorsolateral Prefrontal Cortex | feedforward-glu | uncertain | Primate Control of Grasping (46 -> F6, abstract) |
| NMA | NMA.FD.TH.VA | Ventral Anterior Nucleus | excitatory-glu | uncertain | Primate Control of Grasping (BTH -> F6) |
| NMA.FD.TH.VL | Ventral Lateral Nucleus | excitatory-glu | uncertain | Basal Ganglia Activity (VLo -> SMC, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FEC | FEC.FD.STN.MED | Subthalamic Nucleus Medial | excitatory-glu | uncertain | Serotonin regulation of subthalamic neurons (CTX -> STN, abstract) |
| FEC.FT.PU.MED | Dorsal Putamen Medial | excitatory-glu | uncertain | Primate Control of Grasping (F6 -> BG, abstract) | |
| NMA | NMA.NC.PMC.F4 | Ventral Caudal Premotor Cortex | feedforward-glu | uncertain | Primate Control of Grasping (F6 -> F4) |
| NMA.NC.PMC.F5 | Ventral Rostral Premotor Cortex | feedforward-glu | uncertain | Primate Control of Grasping (F6 -> F5) |
Thirdparty Circuits
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- Serotonin regulation of subthalamic neurons - see Reference (CM.SUBTHALAMUS)
CTX=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia) STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
- Primate Control of Grasping - see Reference (CM.GRASPING-CONTROL)
46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) AIP=Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP BG=Basal Ganglia,FEC.FT.BG BTH=Ventral Anterior Nucleus,NMA.FD.TH.VA F1=Motor Cortex,NMA.NC.MC F2=Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2 F4=Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4 F5=Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5 F6=Pre-Supplementary Motor Area,NMA.NC.SMC.F6 IT=Inferotemporal Area,NSA.NC.IT PIP=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 S2=Primary Somatosensory Cortex,NCP.NC.PG.S1 VC=Occipital Lobe,NC.LOBE.OCC VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP
References
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