BrainRegionLMC HT TG PPN

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Pedunculopontine Tegmental Nuclei

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This page covers biological details of component Pedunculopontine Tegmental Nuclei. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Metencephalon -> Pontine Tegmental Nuclei (HT.TG) -> Pedunculopontine Tegmental Nuclei (LMC.HT.TG.PPN) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Modulatory Contol Area
  • Role: processor.autonomic
  • Function: Provide sensory feedback to cerebral cortex; modulatory
  • Notes to function: contains Rostral (Pars dissipata, anterior, dissipated subnucleus, GABA), Caudal (Pars compacta, anterior, compact subnucleus, ACh)

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Components

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Component items:

  • Entopeduncular Nucleus
  • Peripeduncular Nucleus

Connectivity

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LMC.HT.TG.PPN.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FEC FEC.FT.VP.VM Ventral Pallidum Ventromedial inhibitory-gaba Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VPAL -> PPTG, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FEC FEC.FD.STN.MED Subthalamic Nucleus Medial modulatory-ach Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> STN, abstract)
FEC.FT.SNR.DL Substantia Nigra Pars Reticulata Dorsolateral modulatory-ach Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> SNr, abstract)
LRC LRC.MM.SC.INT Intermediate Superior Colliculus excitatory-glu Geniculate and Extyrageniculate Paths (PPN -> SC, abstract)
NSA NSA.FD.LGN Lateral Geniculate Nucleus excitatory-glu Geniculate and Extyrageniculate Paths (PPN -> LGN)

Thirdparty Circuits

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LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
VC=Occipital Lobe,NC.LOBE.OCC

GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia)
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)

ACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PPTG=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA

CTX=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia)
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)


References

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