BrainCenterNC AL OMPFC

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Orbitomedial Prefrontal Cortex

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This page covers biological details of component group Orbitomedial Prefrontal Cortex. Component group is part of aHuman target integrated biological model.

  • Top-down path to center: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) (see Mind Maps)
  • Function: High-level Motivational Functions

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Components

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Component items:

Connectivity

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Internal Regions Connections:

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Source Region Target Region Reference
Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL) Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR) Regulation of Social Brain (MPFC -> OFC, abstract)
Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM) Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL) Regulation of Social Brain (MPFC -> OFC, abstract)
Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR) Regulation of Social Brain (MPFC -> OFC, abstract)
Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS) Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL) Regulation of Social Brain (MPFC -> OFC, abstract)

External Connections:

unavailable

External Inbound Center Connections:

Source Center Sample Link Reference
Central Extended Amygdala (FAM.FT.CEAM) LMC.FT.NBM -> NDM.NC.AL.FPC Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract)
Septal Nuclei (FAM.FT.SEP) FAM.FT.SEP.DBB -> NDM.NC.AL.VMPFC (unknown reference)
Hypothalamus (FD.HT) LAC.FD.HT.LTN -> NDM.NC.AL.ROFCS Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract)
Cognitive Thalamus (FD.TH.CR) NDM.FD.TH.MDM -> NDM.NC.AL.FPC Amygdala and its network (MD -> MPFC, abstract)
Sensory Thalamus (FD.TH.SR) NDM.FD.TH.SM -> NDM.NC.AL.DMPFC Saccadic Vision (Thalamus -> FrontalCortex, abstract)
Hippocampal Formation (FMM.FT.HF) FMM.FT.HC.CA1P -> NDM.NC.AL.DMPFC Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)
Ventral Tegmental Area (LMC.MM.VTA) LMC.MM.VTA -> NDM.NC.AL.FPC Amygdala and its network (VTA -> MPFC, abstract)
Lateral Prefrontal Cortex (NC.AL.LPFC) NDM.NC.AL.IPG -> NDM.NC.AL.DMPFC (unknown reference)
Insular Cortex (NC.INS) NCP.NC.INS.PPC -> NDM.NC.AL.FPC Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract)
Medial Parietal Lobule (NC.MPL) NCP.NC.MPL.RSC -> NDM.NC.AL.ROFCR Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract)
Parietal Operculum (NC.PO) NCP.NC.PO.PCC -> NDM.NC.AL.ROFCS Global visual system (ParietalCortex -> FrontalCortex, abstract)
Superior Parietal Lobule (NC.SPL) NCP.NC.SPL.SA -> NDM.NC.AL.ROFCM Cortico-Cortical Connectivity (SA -> PFC, abstract)

External Outbound Center Connections:

Target Center Sample Link Reference
Amygdala (FAM.FT.AM) NDM.NC.AL.DMPFC -> FAM.FT.AM.ITC (unknown reference)
Septal Nuclei (FAM.FT.SEP) NDM.NC.AL.FPC -> FAM.FT.SEP.SH (unknown reference)
Hypothalamus (FD.HT) NDM.NC.AL.FPC -> LAC.FD.HT.RCH Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract)
Cognitive Thalamus (FD.TH.CR) NDM.NC.AL.ROFCR -> FMM.FD.TH.RE (unknown reference)
Subthalamus Area (FEC.FD.STA) NDM.NC.AL.ROFCR -> FEC.FD.STN.DL Serotonin regulation of subthalamic neurons (CTX -> STN, abstract)
Basal Ganglia (FEC.FT.BG) NDM.NC.AL.FPC -> FEC.FT.ACC.CORE Affective basal ganglia circuit (OMPFC -> NACC, abstract)
Anterior Cingulate Area (NC.ACG) NDM.NC.AL.DMPFC -> NDM.NC.AL.DACG (unknown reference)
Lateral Prefrontal Cortex (NC.AL.LPFC) NDM.NC.AL.FPC -> NDM.NC.AL.DLPFCR Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)