BrainRegionNDM FD TH MDM

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Medial Mediodorsal Nucleus of Thalamus

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This page covers biological details of component Medial Mediodorsal Nucleus of Thalamus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Thalamus (FD.TH) -> Cognitive Thalamus (FD.TH.CR) -> Mediodorsal Nucleus of Thalamus (FD.TH.MD) -> Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM) (see Mind Maps)
  • Type: nucleus
  • Brain area: Neocortical Brain - Decision Making Area
  • Role: thalamic.cortex.reinforce
  • Function: relay emotional attention to orbitofrontal cortex
  • Notes to function: orbitofrontal cortex (BA12,13) defined by MDm projection; relay AM-Bp to OFC; OFCm - subjective pleasantness, OFCl - subjective unpleasantness

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Components

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  • no child items defined

Connectivity

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NDM.FD.TH.MDM.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.AM.AB Accessory Basal Amygdaloid Nucleus excitatory-glu Prefrontal Cortex (PFC) in emotional behavior (AM -> TH, abstract)
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu Amygdala and its network (BLN -> MD, abstract)
FAM.FT.SEP.MED Medial Septal Nucleus modulatory-ach Thalamocortical relationships (s1MD -> MD, abstract)
FEC FEC.FT.GPI.RM Globus Pallidus Internal Rostromedial inhibitory-gaba Saccadic Vision (BG -> Thalamus, abstract)
FMM FMM.NC.PH.LEC Lateral Entorhinal Cortex excitatory-glu Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract)
FMM.NC.PH.PER Perirhinal Cortex excitatory-glu Contributions of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract)
NCP NCP.NC.MPL.PSCG Posterior Cingulate Cortex excitatory-glu Contributions of Diencephalon to Recognition Memory (PostCingulate -> MDmc, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
NDM NDM.NC.AL.DLPFCR Rostral Mid-Dorsolateral Prefrontal Cortex excitatory-glu Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)
NDM.NC.AL.FPC Lateral Frontopolar Cortex excitatory-glu Amygdala and its network (MD -> MPFC, abstract)

Thirdparty Circuits

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ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HCA=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT=Hypothalamus,FD.HT
LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PCA=Medial Parietal Lobule,NC.MPL
PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei)
TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)

BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP
CEA=Central Amygdala,FAM.FT.AM.CEA (see Amygdala)
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ITC=Inferotemporal Cortex,NSA.NC.IT.TE
LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
LHB=Lateral Habenula,FAM.FD.LHB (see Habenula)
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
STC=Wernicke's area A3,NSA.NC.STG.A3
VGDM=Vagus Nucleus,LAC.HL.VGN
VTA=Ventral Tegmental Area,LMC.MM.VTA

ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV
INS=Insular Cortex,NC.INS
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE
SOL=Solitary Nucleus,LPC.HL.SOL
TH=Thalamus,FD.TH


References

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