BrainCenterFAM FD HB

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Habenula

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This page covers biological details of component group Habenula. Component group is part of aHuman target integrated biological model.

  • Top-down path to center: Forebrain Diencephalon -> Habenula (FAM.FD.HB) (see Mind Maps)
  • Function: Encoding negative feedback

(generated)

Components

(generated)


Component items:

  • Lateral Habenula (FAM.FD.LHB): Encoding negative feedback, direct; motivational control of behavior; pain processing, reward, motivation, and learning
  • Medial Habenula (FAM.FD.MHB): Encoding negative feedback, indirect

Connectivity

(generated)


Internal Regions Connections:

unavailable


Source Region Target Region Reference
Medial Habenula (FAM.FD.MHB) Lateral Habenula Medial Part (FAM.FD.LHB.MED) Connectivity map of the habenula (M -> L, abstract)

External Connections:

unavailable

External Inbound Center Connections:

Source Center Sample Link Reference
Central Extended Amygdala (FAM.FT.CEAM) FAM.FT.EPF -> FAM.FD.LHB.LT Regulation of the rapid eye movement (REM) sleep by habenular projection (EPN -> LHbL)
Septal Nuclei (FAM.FT.SEP) FAM.FT.SEP.LT -> FAM.FD.LHB.MED Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM)
Hypothalamus (FD.HT) LAC.FD.HT.VLPO -> FAM.FD.LHB.LT Habenula Connections (LPO -> LHb, abstract)
Basal Ganglia (FEC.FT.BG) FEC.FT.GPI.DS -> FAM.FD.LHB.LT Habenula Connections (GPi -> LHb, abstract)
Locus Coeruleus (LMC.HT.LC) LMC.HT.LC -> FAM.FD.LHB.LT Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)

External Outbound Center Connections:

Target Center Sample Link Reference
Basal Ganglia (FEC.FT.BG) FAM.FD.LHB.MED -> FEC.FT.SNC.LT Habenula Connections (LHb -> SNc, abstract)
Medullary Reticular Formation (HL.RF) FAM.FD.LHB.MED -> LMC.HL.RP.MG Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> MRN, abstract)
Pontine Tegmental Nuclei (HT.TG) FAM.FD.LHB.LT -> FEC.HT.TG.RMTG Both LHb and MHb control the dopaminergic and serotonergic systems (LHbL -> RMTg)
Ventral Tegmental Area (LMC.MM.VTA) FAM.FD.LHB.MED -> LMC.MM.VTA Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> VTA)
Mesencephalic Reticular Formation (MM.RF) FAM.FD.LHB.MED -> LMC.MM.RP.DRN Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN)
Endocrine Glands (TARGET.TEA.ENDOCRINE) FAM.FD.MHB -> TARGET.TEA.ENDOCRINE Habenula Connections (MHb -> PB)