BrainRegionFAM FD LHB MED

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Lateral Habenula Medial Part

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This page covers biological details of component Lateral Habenula Medial Part. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Habenula (FAM.FD.HB) -> Lateral Habenula (FAM.FD.LHB) -> Lateral Habenula Medial Part (FAM.FD.LHB.MED) (see Mind Maps)
  • Type: nucleus
  • Brain area: Forebrain - Affective Motivations Area
  • Role: processor.affective.avoidance
  • Function: Encoding negative feedback, direct, Septal

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Components

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  • no child items defined

Connectivity

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FAM.FD.LHB.MED.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FD.MHB Medial Habenula excitatory-glu Connectivity map of the habenula (M -> L, abstract)
FAM.FT.SEP.DBB Diagonal Band of Broca inhibitory-gaba Both LHb and MHb control the dopaminergic and serotonergic systems (DBB -> LHbM)
FAM.FT.SEP.LT Lateral Septal Nucleus inhibitory-gaba Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM)
FEC FEC.FT.VP.VM Ventral Pallidum Ventromedial inhibitory-gaba Both LHb and MHb control the dopaminergic and serotonergic systems (VP -> LHbM, abstract)
LAC LAC.FD.HT.LTN Lateral Hypothalamic Nucleus excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)
LAC.FD.HT.VLPO Ventrolateral Preoptic Nucleus excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LPO -> LHbM)
LMC LMC.HT.LC Locus Coeruleus modulatory-ne Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.HT.TG.NI Incertus Nucleus excitatory-glu Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> NI)
FEC FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral excitatory-glu Habenula Connections (LHb -> SNc, abstract)
FEC.HT.TG.RMTG Rostromedial Tegmental Nucleus excitatory-glu Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> RMTg)
LMC LMC.HL.RP.MG Raphe Magnus Nucleus excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> MRN, abstract)
LMC.HT.TG.LDT Laterodorsal Tegmental Nucleus excitatory-glu Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)
LMC.MM.RP.DRN Dorsal Raphe Nucleus excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN)
LMC.MM.RP.SUC Superior Central Raphe Nucleus excitatory-glu Habenula Connections (LHb -> MR, abstract)
LMC.MM.VTA Ventral Tegmental Area excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> VTA)

Thirdparty Circuits

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DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DTG=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EPN=Endopiriform Nucleus,FAM.FT.EPF
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
LHT=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT
LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED
NI=Incertus Nucleus,FAM.HT.TG.NI
RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA
VTG=Ventral Tegmental Area,LMC.MM.VTG

DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT
LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
LS=Lateral Septal Nucleus,FAM.FT.SEP.LT
MHb=Medial Habenula,FAM.FD.MHB
MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
MS=Medial Septal Nucleus,FAM.FT.SEP.MED
PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei)
RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA

CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
IP=Interpeduncular Nucleus,FEC.HT.TG.IPD
LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
LHb=Lateral Habenula,FAM.FD.LHB (see Habenula)
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
MHb=Medial Habenula,FAM.FD.MHB
MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC
PB=Endocrine Glands,TARGET.TEA.ENDOCRINE
S=Septal Nuclei,FAM.FT.SEP
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
VTA=Ventral Tegmental Area,LMC.MM.VTA


References

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