BrainCenterNC AL LPFC

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Lateral Prefrontal Cortex

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This page covers biological details of component group Lateral Prefrontal Cortex. Component group is part of aHuman target integrated biological model.

  • Top-down path to center: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Lateral Prefrontal Cortex (NC.AL.LPFC) (see Mind Maps)
  • Function: High-level Rational Thinking Functions

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Components

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Component items:

Connectivity

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Internal Regions Connections:

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Source Region Target Region Reference
Inferior Prefrontal Gyrus (NDM.NC.AL.IPG) Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL) Directed Effort Network (fPole -> DLPFC, abstract)

External Connections:

unavailable

External Inbound Center Connections:

Source Center Sample Link Reference
Cognitive Thalamus (FD.TH.CR) NDM.FD.TH.MDM -> NDM.NC.AL.DLPFCR Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)
Sensory Thalamus (FD.TH.SR) NPE.FD.TH.MPV -> NDM.NC.AL.DLPFCL Saccadic Vision (Thalamus -> FrontalCortex, abstract)
Cerebellar Complex (LLC.HT.CRC) LLC.HT.CR.DN -> NDM.NC.AL.DLPFCL (unknown reference)
Anterior Cingulate Area (NC.ACG) NDM.NC.AL.VACG -> NDM.NC.AL.DLPFCR Role for serotonin in moral behavior (ACG -> LPFC, abstract)
Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) NDM.NC.AL.FPC -> NDM.NC.AL.DLPFCR Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)
Insular Cortex (NC.INS) NCP.NC.INS.AIC -> NDM.NC.AL.IPG Directed Effort Network (Insula -> fPole, abstract)
Inferior Parietal Lobule (NC.IPL) NPE.NC.IPL.MST -> NDM.NC.AL.DLPFCR Cortico-Cortical Connectivity (PTHA -> PFC, abstract)
Occipital Lobe (NC.LOBE.OCC) NSA.NC.OCC.V2TN -> NDM.NC.AL.DLPFCL Cortico-Cortical Connectivity (VA -> PFC, abstract)
Medial Parietal Lobule (NC.MPL) NCP.NC.MPL.RSC -> NDM.NC.AL.DLPFCR Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract)
Premotor Cortex (NC.PMC) NMA.NC.PMC.F4 -> NDM.NC.AL.DLPFCL Cortico-Cortical Connectivity (MA -> PFC, abstract)
Superior Temporal Gyrus (NC.STG) NCP.NC.TPC -> NDM.NC.AL.IPG Language-Related Regions (TC -> vIFC)
Intraparietal Sulcus (NSA.NC.IPS) NPE.NC.IPS.LIP -> NDM.NC.AL.DLPFCR Summary of eye movement control (PEF -> DLPFC, abstract)
Inferotemporal Area (NSA.NC.IT) NSA.NC.IT.TE -> NDM.NC.AL.DLPFCL 3 Visual Cortex Paths (IT -> LPC, abstract)

External Outbound Center Connections:

Target Center Sample Link Reference
Motor Thalamus (FD.TH.MR) NDM.NC.AL.DLPFCL -> NMA.FD.TH.VA Prefrontal Cortex (PFC) in motor behavior (LPFC -> TH, abstract)
Basal Ganglia (FEC.FT.BG) NDM.NC.AL.DLPFCL -> FEC.FT.CN.HD Global visual system (FrontalCortex -> BGA, abstract)
Pontine Reticular Formation (HT.RF) NPE.NC.BRA.PO -> LLC.HT.PRF.RTMG Motor neurons control (CTX -> PRF, abstract)
Anterior Cingulate Area (NC.ACG) NDM.NC.AL.DLPFCR -> NDM.NC.AL.DACG Prefrontal Cortex (PFC) in emotional behavior (LPFC -> ACG, abstract)
Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) NDM.NC.AL.DLPFCR -> NDM.NC.AL.VMPFC Fear regulation (dlPFC -> vmPFC, abstract)
Inferior Parietal Lobule (NC.IPL) NPE.NC.BRA.PT -> NPE.NC.IPL.SMW Cortical Auditory System (IFC44 -> IPL40, abstract)
Premotor Cortex (NC.PMC) NDM.NC.AL.DLPFCL -> NMA.NC.PMC.F5 Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)
Supplementary Motor Cortex (NMA.NC.SMC) NDM.NC.AL.DLPFCR -> NMA.NC.SMC.F6 Primate Control of Grasping (46 -> F6, abstract)