BrainRegionLLC HT CR DN

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Dentate Nucleus

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This page covers biological details of component Dentate Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Metencephalon -> Cerebellar Complex (LLC.HT.CRC) -> Deep Cerebellar Nuclei (LLC.HT.CR.DCN) -> Dentate Nucleus (LLC.HT.CR.DN) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Locomotion Control Area (LLC)
  • Area circuit: Cerebrocerebellar Locomotion (LLC)
  • Role: processor.automatic
  • Function: planning, initiation and control of voluntary movements
  • Notes to function:
    • dorsal - movement of skeletal muscle, ventral - conscious thought and visuospatial function

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Components

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Component items:

  • Amiculum of Dentate Nucleus
  • Hilum of Dentate Nucleus
  • Neodentate Part of Dentate Nucleus
  • Paleodentate of Dentate Nucleus

Connectivity

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LLC.HT.CR.DN.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
LLC LLC.HT.CR.CC Cerebellar Lateral Lobe inhibitory-gaba uncertain Cerebellum functional divisions (CRP -> DN)
LLC.HT.PN.RSP Rostral Pontine Nucleus excitatory-glu uncertain Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
LLC LLC.HT.CR.GN Globose Nucleus excitatory-glu uncertain (unknown reference)
LLC.MM.RD.PV Parvocellular Part of Red Nucleus excitatory-glu uncertain Motor neurons control (LT -> RD, abstract)
NCP NCP.FD.TH.RIL Rostral Intralaminar Nuclear Group of Thalamus excitatory-glu uncertain (unknown reference)
NDM NDM.NC.AL.DLPFCL Lateral Mid-Dorsolateral Prefrontal Cortex excitatory-glu uncertain (unknown reference)
NMA NMA.FD.TH.VL Ventral Lateral Nucleus excitatory-glu uncertain Thalamocortical relationships (s1VL -> VL)

Thirdparty Circuits

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CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
CTX=Anterior Lobe,NC.LOBE.ANT
EAMN=Anterior/Ventral Horn,SC.VH
EGMN=Anterior/Ventral Horn,SC.VH
FAMN=Anterior/Ventral Horn,SC.VH
FG=Fastigual Nucleus,LRC.HT.CR.FG
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
MRF=Medullary Reticular Formation,HL.RF
PRF=Pontine Reticular Formation,HT.RF
RD=Red Nucleus,LLC.MM.RD
VB=Vestibular Nuclei,LPC.HT.VBN

A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MGN=Medial Geniculate Body,NSA.FD.TH.MGB
P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus)
VA=Ventral Anterior Nucleus,NMA.FD.TH.VA
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia)
pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
pLGN=Primary Visual Cortex,NSA.NC.OCC.V1
pLP=Superior Parietal Lobule,NC.SPL
pMD=Prefrontal Cortex,NC.AL.PFC
pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1
pP=Insular Cortex,NC.INS
pVA=Supplementary Motor Cortex,NMA.NC.SMC
pVL=Motor Cortex,NMA.NC.MC
pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1
pVPM=Precentral Cortex,NCP.NC.PO.PCC
s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
s1MD=Septal Nuclei,FAM.FT.SEP
s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV
s1VL=Dentate Nucleus,LLC.HT.CR.DN
s2A=Mammillary Body,FD.MB (see Hypothalamus)
s2MD=Piriform Cortex,NSA.NC.PH.PIR
s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR
s2VL=Basal Ganglia,FEC.FT.BG
s3MD=Prefrontal Cortex,NC.AL.PFC
sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
sLD=Superior Parietal Lobule,NC.SPL
sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
sVA=Basal Ganglia,FEC.FT.BG
sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn)
sVPM=Solitary Nucleus,LPC.HL.SOL

CCV=Central Cervical Nucleus,LPC.SC.IZ.CCV
CRP=Cerebellar Lateral Lobe,LLC.HT.CR.CC
CRS=Cerebellar Paravermis,LLC.HT.CR.PV
CRV=Cerebellar Vermis,LRC.HT.CR.VM
CTX=Anterior Lobe,NC.LOBE.ANT
DN=Dentate Nucleus,LLC.HT.CR.DN
FG=Fastigual Nucleus,LRC.HT.CR.FG
IO=Inferior Olivary Nucleus,LLC.HL.IO
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
PNN=Basilar Pontine Nuclei,LLC.HT.BPN
RD=Red Nucleus,LLC.MM.RD
RF=Pontine Reticular Formation,HT.RF
SCM=Anterior/Ventral Horn,SC.VH
SCS=Proprius Nucleus,LPC.SC.PH.NP
SCSD=Clarke Nucleus,LPC.SC.PH.CL
VB=Vestibular Nuclei,LPC.HT.VBN
VBG=Vestibular Ganglion,LPC.PN.SG.VB
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL


References

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