BrainAreaLLC

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Locomotion Control Area

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Local Circuits

(generated)

ID Name Regions
LLC Cerebrocerebellar Locomotion LLC.HT.BPN, LLC.HT.CR.CC, LLC.HT.CR.DN, LLC.HT.PN.RSP, LLC.HT.PRF.RTMG
LLL Spinocerebellar Learning LLC.FD.TH.SF, LLC.HL.ARC, LLC.HL.IO, LLC.HL.RF.MLRN, LLC.HL.RF.PLRN, LLC.HT.PN.PBB
LLS Spinocerebellar Locomotion LLC.HT.CR.EN, LLC.HT.CR.GN, LLC.HT.CR.PV, LLC.MM.RD

Cerebrocerebellar Locomotion

unavailable

Component ID Component Name Type Service Function Comments
LLC.HT.BPN Basilar Pontine Nuclei nucleus LUS convey information from motor cortex to cerebellum regarding intended movements
of contralateral arm and leg
receive neocortical input and give rise to many
axons that cross the midline to enter the
contralateral cerebellum
LLC.HT.CR.CC Cerebellar Lateral Lobe cortex LLC planning movement that is about to occur, evaluating sensory information for
action, handles intentions
lateral zone of anterior and posterior lobes;
dentate nucleus; receives input exclusively from
cerebral cortex (especially parietal lobe) via
pontine nuclei (forming cortico-ponto-cerebellar
pathways), and sends output mainly to ventrolateral
thalamus and to red nucleus; add skill to movements
LLC.HT.CR.DN Dentate Nucleus nucleus LLC planning, initiation and control of voluntary movements dorsal - movement of skeletal muscle, ventral -
conscious thought and visuospatial function
LLC.HT.PN.RSP Rostral Pontine Nucleus nucleus LLI Part of learning, motivation, spatial memory pathway Relay from mammillary body to CR
LLC.HT.PRF.RTMG Pontine Reticulotegmental Nucleus nucleus LLI Mediate saccadic eye movements Inactivation leads to deficit of expression, but
not learning

Internal Region Connections:

Source Region Target Region Type Reference
LLC.HT.BPN LLC.HT.CR.CC nucleus-allocortex Cerebellum functional divisions (PNN -> CRP)
LLC.HT.CR.CC LLC.HT.CR.DN allocortex-nucleus-gaba Cerebellum functional divisions (CRP -> DN)
LLC.HT.PN.RSP LLC.HT.CR.DN nucleus-nucleus Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NDM LLC.HT.PRF.RTMG NDM.NC.AL.VACG Ventral Anterior Cingulate Area neocortex-nucleus Motor neurons control (CTX -> PRF, abstract)
NMA LLC.HT.BPN NMA.NC.MC Motor Cortex neocortex-nucleus Cerebellum functional divisions (CTX -> PNN, abstract)
LLC.HT.PRF.RTMG NMA.NC.MC Motor Cortex neocortex-nucleus Motor neurons control (CTX -> PRF, abstract)
NMA.NC.SMC.F3 Supplementary Motor Area neocortex-nucleus Motor neurons control (CTX -> PRF, abstract)
NPE LLC.HT.PRF.RTMG NPE.NC.BRA.PO Broca's Area Pars Opercularis neocortex-nucleus Motor neurons control (CTX -> PRF, abstract)
Subcortical
FEC LLC.HT.CR.CC FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral nucleus-allocortex-DA Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)
FMM LLC.HT.PN.RSP FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus Prefrontal Cortex (PFC) in emotional behavior (HT -> PN, abstract)
LLC.HT.PRF.RTMG FMM.FD.MB.LMB Lateral Mammillary Nucleus nucleus-nucleus Mammillary Body (LMB -> RTG)
FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus Mammillary Body (MMB -> RTG)
LAC LLC.HT.PN.RSP LAC.FD.HT.RCH Retrochiasmatic Nucleus nucleus-nucleus Prefrontal Cortex (PFC) in emotional behavior (HT -> PN, abstract)
LLC LLC.HT.CR.CC LLC.HL.IO Inferior Olivary Nucleus nucleus-allocortex Cerebellum functional divisions (IO -> CRP)
LPC LLC.HT.PRF.RTMG LPC.HL.TGS.STR Spinal Trigeminal Nucleus nucleus-nucleus Eye blink reflex and pupillary light reflex (SpinalTrigeminal -> RF, abstract)
LRC LLC.HT.CR.CC LRC.HT.PRF.RPO Oral Pontine Reticular Nucleus nucleus-allocortex Saccades and smooth movements (DLPN -> CR, abstract)
LLC.HT.PRF.RTMG LRC.MM.SC.DEEP Deep Superior Colliculus nucleus-nucleus Geniculate and Extyrageniculate Paths (SC -> RF, abstract)
LRC.MM.SC.INT Intermediate Superior Colliculus nucleus-nucleus Geniculate and Extyrageniculate Paths (SC -> RF, abstract)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Cortical
NCP LLC.HT.CR.DN NCP.FD.TH.RIL Rostral Intralaminar Nuclear Group of Thalamus nucleus-nucleus (unknown reference)
NDM LLC.HT.CR.DN NDM.NC.AL.DLPFCL Lateral Mid-Dorsolateral Prefrontal Cortex nucleus-neocortex (unknown reference)
NMA LLC.HT.CR.DN NMA.FD.TH.VL Ventral Lateral Nucleus nucleus-nucleus Thalamocortical relationships (s1VL -> VL)
Subcortical
LLC LLC.HT.CR.DN LLC.HT.CR.GN Globose Nucleus nucleus-nucleus (unknown reference)
LLC.MM.RD Red Nucleus nucleus-nucleus Motor neurons control (LT -> RD)
LRC LLC.HT.BPN LRC.MM.SC.INT Intermediate Superior Colliculus nucleus-nucleus (unknown reference)
LLC.HT.PRF.RTMG LRC.HT.CR.FN Cerebellar Flocconodular Lobe nucleus-nucleus-gaba (unknown reference)
LRC.HT.CR.VM Cerebellar Vermis nucleus-allocortex-gaba (unknown reference)

Spinocerebellar Learning

unavailable

Component ID Component Name Type Service Function Comments
LLC.FD.TH.SF Subfascicular Nucleus of Thalamus nucleus LUS Relays from PAG to Rhape nuclei, Inferior olive nucleus
LLC.HL.ARC Arcuate Nucleus of Medulla nucleus LLI Relay cardiorepriratory proprioception to cerebellum Receives fibers from spinothalamic tract and sends
to CR; controlling respiratory frequency;
chemosensitivity and cardiorespiratory activity
LLC.HL.IO Inferior Olivary Nucleus nucleus LLI Proprioception Relay from Spinal Cord to Cerebellum
LLC.HL.RF.MLRN Lateral Reticular Nucleus, Magnocellular nucleus LLI spinal cord projections to cerebellum, cervical from RD; medial, magnocellular portion, immediately
adjacent to lateral - to vermis; rest of
magnocellular subnucleus sends its projections to
hemisphere regions of cerebellum
LLC.HL.RF.PLRN Lateral Reticular Nucleus, Parvocellular nucleus LLI spinal cord projections to cerebellum, thoracolumbar from RD; lateral, parvocellular portion of LRN send
most their projections to vermis of cerebellum
LLC.HT.PN.PBB Pontobulbar Body nucleus LLI Relay neck proprioception to cerebellum Walking, speaking, breathing, part of
corticopontocerebellar pathway

Internal Region Connections:

Source Region Target Region Type Reference
LLC.FD.TH.SF LLC.HL.IO nucleus-nucleus-gaba (unknown reference)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NMA LLC.HT.PN.PBB NMA.NC.MC Motor Cortex neocortex-nucleus Prefrontal Cortex (PFC) in motor behavior (MC -> PN, abstract)
Subcortical
LLC LLC.HL.IO LLC.MM.RD Red Nucleus nucleus-nucleus Cerebellum functional divisions (RD -> IO)
LLC.HL.RF.MLRN LLC.MM.RD Red Nucleus nucleus-nucleus (unknown reference)
LLC.HL.RF.PLRN LLC.MM.RD Red Nucleus nucleus-nucleus (unknown reference)
LMC LLC.FD.TH.SF LMC.MM.PAG Periaqueductal Gray Matter nucleus-nucleus-ENK (unknown reference)
LPC LLC.HL.ARC LPC.SC.PH.CL Clarke Nucleus nucleus-nucleus (unknown reference)
LLC.HL.IO LPC.SC.IZ.CCV Central Cervical Nucleus nucleus-nucleus (unknown reference)
LPC.SC.PH.NP Proprius Nucleus nucleus-nucleus Cerebellum functional divisions (SCS -> IO)
LLC.HL.RF.PLRN LPC.SC.IZ.IMM Intermediomedial Nucleus nucleus-nucleus (unknown reference)
LLC.HT.PN.PBB LPC.SC.PH.CL Clarke Nucleus nucleus-nucleus (unknown reference)
LRC LLC.HL.IO LRC.MM.DSCH Darkschewitsch Nucleus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
LLC LLC.HL.ARC LLC.HT.CR.PV Cerebellar Paravermis nucleus-allocortex (unknown reference)
LLC.HL.IO LLC.HT.CR.CC Cerebellar Lateral Lobe nucleus-allocortex Cerebellum functional divisions (IO -> CRP)
LLC.HT.CR.GN Globose Nucleus nucleus-nucleus (unknown reference)
LLC.HT.CR.PV Cerebellar Paravermis nucleus-allocortex Cerebellum functional divisions (IO -> CRS)
LLC.HL.RF.MLRN LLC.HT.CR.PV Cerebellar Paravermis nucleus-allocortex (unknown reference)
LLC.HL.RF.PLRN LLC.HT.CR.PV Cerebellar Paravermis nucleus-allocortex (unknown reference)
LLC.HT.PN.PBB LLC.HT.CR.PV Cerebellar Paravermis nucleus-allocortex Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)
LMC LLC.FD.TH.SF LMC.MM.RP.DRN Dorsal Raphe Nucleus nucleus-nucleus-gaba (unknown reference)
LRC LLC.HL.IO LRC.HT.CR.VM Cerebellar Vermis nucleus-allocortex Cerebellum functional divisions (IO -> CRV)

Spinocerebellar Locomotion

unavailable

Component ID Component Name Type Service Function Comments
LLC.HT.CR.EN Emboliform Nucleus nucleus LLC Modulate motor functions of Red Nucleus Trigeminocerebellar tract
LLC.HT.CR.GN Globose Nucleus nucleus LLC Modulate motor functions of Red Nucleus
LLC.HT.CR.PV Cerebellar Paravermis cortex LLC fine-tune body and limb movements medial zone of anterior and posterior lobes;
interpositus (emboliform and globose) nuclei; tunes
and adjusts ongoing movements and muscle tone
LLC.MM.RD Red Nucleus nucleus LLE Motor coordination Crawling of babies is controlled by RN

Internal Region Connections:

Source Region Target Region Type Reference
LLC.HT.CR.EN LLC.HT.CR.GN nucleus-nucleus (unknown reference)
LLC.MM.RD nucleus-nucleus Cerebellum functional divisions (IP -> RD, abstract)
LLC.HT.CR.GN LLC.MM.RD nucleus-nucleus Cerebellum functional divisions (IP -> RD, abstract)
LLC.HT.CR.PV LLC.HT.CR.EN allocortex-nucleus-gaba Cerebellum functional divisions (CRS -> IP, abstract)
LLC.HT.CR.GN allocortex-nucleus-gaba Cerebellum functional divisions (CRS -> IP, abstract)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NDM LLC.MM.RD NDM.NC.AL.VACG Ventral Anterior Cingulate Area neocortex-nucleus Cerebellum functional divisions (CTX -> RD, abstract)
Subcortical
FEC LLC.MM.RD FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral nucleus-nucleus-DA (unknown reference)
LLC LLC.HT.CR.GN LLC.HL.IO Inferior Olivary Nucleus nucleus-nucleus (unknown reference)
LLC.HT.CR.DN Dentate Nucleus nucleus-nucleus (unknown reference)
LLC.HT.CR.PV LLC.HL.ARC Arcuate Nucleus of Medulla nucleus-allocortex (unknown reference)
LLC.HL.IO Inferior Olivary Nucleus nucleus-allocortex Cerebellum functional divisions (IO -> CRS)
LLC.HL.RF.MLRN Lateral Reticular Nucleus, Magnocellular nucleus-allocortex (unknown reference)
LLC.HL.RF.PLRN Lateral Reticular Nucleus, Parvocellular nucleus-allocortex (unknown reference)
LLC.HT.PN.PBB Pontobulbar Body nucleus-allocortex Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)
LLC.MM.RD LLC.HT.CR.DN Dentate Nucleus nucleus-nucleus Motor neurons control (LT -> RD)
LMC LLC.HT.CR.PV LMC.HL.RP.OB Raphe Obscurus Nucleus nucleus-allocortex-5HT (unknown reference)
LMC.HP.RP.PRN Pontine Raphe Nucleus nucleus-allocortex-5HT (unknown reference)
LPC LLC.HT.CR.PV LPC.HL.ACU Accessory Cuneate Nucleus nucleus-allocortex (unknown reference)
LPC.HL.CU Cuneate Nucleus nucleus-allocortex (unknown reference)
LPC.SC.IZ.CBS Centrobasalis Nucleus nucleus-allocortex (unknown reference)
LPC.SC.IZ.CCV Central Cervical Nucleus nucleus-allocortex Cerebellum functional divisions (CCV -> CRS)
LPC.SC.IZ.IMM Intermediomedial Nucleus nucleus-allocortex (unknown reference)
LPC.SC.PH.CL Clarke Nucleus nucleus-allocortex Afferent pain pathways (SC -> Cerebellum, abstract)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FEC LLC.HT.CR.EN FEC.FD.TH.CM Centromedian Nucleus of Thalamus nucleus-nucleus (unknown reference)
LLC LLC.MM.RD LLC.HL.IO Inferior Olivary Nucleus nucleus-nucleus Cerebellum functional divisions (RD -> IO)
LLC.HL.RF.MLRN Lateral Reticular Nucleus, Magnocellular nucleus-nucleus (unknown reference)
LLC.HL.RF.PLRN Lateral Reticular Nucleus, Parvocellular nucleus-nucleus (unknown reference)
LPC LLC.MM.RD LPC.SC.VH.PL Posterolateral Nucleus nucleus-nucleus Motor neurons control (RD -> FAMN, abstract)
LPC.SC.VH.PM Posteromedial Nucleus nucleus-nucleus Motor neurons control (RD -> FAMN, abstract)
LRC LLC.HT.CR.EN LRC.MM.SC.INT Intermediate Superior Colliculus nucleus-nucleus (unknown reference)
LLC.HT.CR.GN LRC.MM.DSCH Darkschewitsch Nucleus nucleus-nucleus (unknown reference)
LRC.MM.SC.DEEP Deep Superior Colliculus nucleus-nucleus (unknown reference)
LLC.HT.CR.PV LRC.HT.CR.FG Fastigual Nucleus allocortex-nucleus Cerebellum functional divisions (CRS -> FG)

Thirdparty Circuits

(generated)

CCV=Central Cervical Nucleus,LPC.SC.IZ.CCV
CRP=Cerebellar Lateral Lobe,LLC.HT.CR.CC
CRS=Cerebellar Paravermis,LLC.HT.CR.PV
CRV=Cerebellar Vermis,LRC.HT.CR.VM
CTX=Anterior Lobe,NC.LOBE.ANT
DN=Dentate Nucleus,LLC.HT.CR.DN
FG=Fastigual Nucleus,LRC.HT.CR.FG
IO=Inferior Olivary Nucleus,LLC.HL.IO
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
PNN=Basilar Pontine Nuclei,LLC.HT.BPN
RD=Red Nucleus,LLC.MM.RD
RF=Pontine Reticular Formation,HT.RF
SCM=Anterior/Ventral Horn,SC.VH
SCS=Proprius Nucleus,LPC.SC.PH.NP
SCSD=Clarke Nucleus,LPC.SC.PH.CL
VB=Vestibular Nuclei,LPC.HT.VBN
VBG=Vestibular Ganglion,LPC.PN.SG.VB
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL

CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
CTX=Anterior Lobe,NC.LOBE.ANT
EAMN=Anterior/Ventral Horn,SC.VH
EGMN=Anterior/Ventral Horn,SC.VH
FAMN=Anterior/Ventral Horn,SC.VH
FG=Fastigual Nucleus,LRC.HT.CR.FG
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
MRF=Medullary Reticular Formation,HL.RF
PRF=Pontine Reticular Formation,HT.RF
RD=Red Nucleus,LLC.MM.RD
VB=Vestibular Nuclei,LPC.HT.VBN

LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
RTG=Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG

Bechterew=Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
FEFSEF=Anterior Lobe,NC.LOBE.ANT
LGB=Lateral Geniculate Nucleus,NSA.FD.LGN
PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation)
PrimaryVisual=Primary Visual Cortex,NSA.NC.OCC.V1
RIP=Raphe Interpositus Nucleus,LRC.MM.RP.RIP
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
Vestibular=Superior Vestibular Nucleus,LPC.HT.SVBN
VisualAssociation=Caudal Precuneus,NPE.NC.SPL.PG

A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MGN=Medial Geniculate Body,NSA.FD.TH.MGB
P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus)
VA=Ventral Anterior Nucleus,NMA.FD.TH.VA
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia)
pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
pLGN=Primary Visual Cortex,NSA.NC.OCC.V1
pLP=Superior Parietal Lobule,NC.SPL
pMD=Prefrontal Cortex,NC.AL.PFC
pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1
pP=Insular Cortex,NC.INS
pVA=Supplementary Motor Cortex,NMA.NC.SMC
pVL=Motor Cortex,NMA.NC.MC
pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1
pVPM=Precentral Cortex,NCP.NC.PO.PCC
s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
s1MD=Septal Nuclei,FAM.FT.SEP
s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV
s1VL=Dentate Nucleus,LLC.HT.CR.DN
s2A=Mammillary Body,FD.MB (see Hypothalamus)
s2MD=Piriform Cortex,NSA.NC.PH.PIR
s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR
s2VL=Basal Ganglia,FEC.FT.BG
s3MD=Prefrontal Cortex,NC.AL.PFC
sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
sLD=Superior Parietal Lobule,NC.SPL
sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
sVA=Basal Ganglia,FEC.FT.BG
sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn)
sVPM=Solitary Nucleus,LPC.HL.SOL


References

(generated)