BrainRegionNMA NC SMC F3

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Supplementary Motor Area

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This page covers biological details of component Supplementary Motor Area. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Supplementary Motor Cortex (NMA.NC.SMC) -> Supplementary Motor Area (NMA.NC.SMC.F3) (see Mind Maps)
  • Type: cortex
  • Brain area: Neocortical Brain - Motor Aggregation Area
  • Brodmann ID: 06
  • Role: cortex.generic
  • Function: Movement execution; Numerical and verbal mental-operation tasks
  • Notes to function: from TH/VLo from from putamen; F1/F2/F4/24d - strong; F6/F7/F5/24c - modest; no input from the prefrontal lobe




  • no child items defined



Inbound Region Connections:

Source Area Source Region Source Name Type Reference
NMA NMA.FD.TH.VA Ventral Anterior Nucleus excitatory-glu Thalamocortical relationships (VA -> pVA, abstract)
NMA.NC.PMC.F4 Ventral Caudal Premotor Cortex feedforward-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FEC FEC.FT.PU.MED Dorsal Putamen Medial excitatory-glu Global visual system (FrontalCortex -> BGA, abstract)
LLC LLC.HT.PRF.RTMG Pontine Reticulotegmental Nucleus excitatory-glu Motor neurons control (CTX -> PRF, abstract)
LRC LRC.HL.PRF.GCR Gigantocellular Reticular Nucleus excitatory-glu Motor neurons control (CTX -> MRF, abstract)
LRC.HT.PRF.CRF Caudal Pontine Reticular Nucleus excitatory-glu Motor neurons control (CTX -> PRF, abstract)
NMA NMA.NC.PMC.F2 Dorsal Caudal Premotor Cortex feedforward-glu 3 Visual Cortex Paths (pre-SMA -> dPM, abstract)
NMA.NC.PMC.F5 Ventral Rostral Premotor Cortex feedforward-glu 3 Visual Cortex Paths (pre-SMA -> vPM, abstract)

Thirdparty Circuits


ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
BGA=Basal Ganglia,FEC.FT.BG
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OPN=Oculomotor Nucleus,LPC.MM.OCN
ParietalCortex=Parietal Lobe,NC.LOBE.PAR
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
VisualCortex=Occipital Lobe,NC.LOBE.OCC

IPL=Inferior Parietal Lobule,NC.IPL
IPS=Intraparietal Sulcus,NSA.NC.IPS
IT=Inferotemporal Area,NSA.NC.IT
LPC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
MI=Motor Cortex,NMA.NC.MC
OCC=Occipital Lobe,NC.LOBE.OCC
SPL=Superior Parietal Lobule,NC.SPL
dPM=Dorsal Premotor Cortex,MCA.NC.DPMC (see Premotor Cortex)
pre-SMA=Supplementary Motor Cortex,NMA.NC.SMC
vPM=Ventral Premotor Cortex,MCA.NC.VPMC (see Premotor Cortex)

CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
CTX=Anterior Lobe,NC.LOBE.ANT
EAMN=Anterior/Ventral Horn,SC.VH
EGMN=Anterior/Ventral Horn,SC.VH
FAMN=Anterior/Ventral Horn,SC.VH
FG=Fastigual Nucleus,LRC.HT.CR.FG
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
MRF=Medullary Reticular Formation,HL.RF
PRF=Pontine Reticular Formation,HT.RF
RD=Red Nucleus,LLC.MM.RD
VB=Vestibular Nuclei,LPC.HT.VBN