From aHuman Wiki
Jump to: navigation, search
Gigantocellular Reticular Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLRC -> BrainRegionLRC_HL_PRF_GCR

This page covers biological details of component Gigantocellular Reticular Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Myelencephalon -> Medullary Reticular Formation (HL.RF) -> Medullary Reticular Formation, Medial Column (HL.RF.MED) -> Gigantocellular Reticular Nucleus (LRC.HL.PRF.GCR) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Motor Reflex Area (LRC)
  • Area circuit: Postural Control Reflexes (LRP)
  • Role: subcortical.motor.flexor
  • Function: Vasodepressor center
  • Notes to function:
    • Projects to hypoglossal nucleus, abducens
    • medullary (lateral) reticulospinal tract
    • excite trunk flexors, inhibit extensors
    • stimulation induces inspiration




  • no child items defined



Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
LPC LPC.HL.TGS.STR Spinal Trigeminal Nucleus excitatory-glu uncertain (unknown reference)
LRC LRC.MM.CNF Cuneiform Nucleus excitatory-glu uncertain (unknown reference)
NMA NMA.NC.SMC.F3 Supplementary Motor Area excitatory-glu uncertain Motor neurons control (CTX -> MRF, abstract)
NPE NPE.NC.PMC.AFEF Anterior Frontal Eye Field excitatory-glu uncertain Motor neurons control (CTX -> MRF, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
LPC LPC.SC.VH.PL Posterolateral Nucleus excitatory-glu uncertain Motor neurons control (MRF -> EGMN, abstract)
LPC.SC.VH.PM Posteromedial Nucleus excitatory-glu uncertain Motor neurons control (MRF -> EGMN, abstract)
LRC LRC.HL.RF.MED Central Medullary Reticular Nucleus excitatory-glu uncertain (unknown reference)
LRC.MM.SCNF Subcuneiform Nucleus excitatory-glu uncertain (unknown reference)

Thirdparty Circuits


CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
CTX=Anterior Lobe,NC.LOBE.ANT
EAMN=Anterior/Ventral Horn,SC.VH
EGMN=Anterior/Ventral Horn,SC.VH
FAMN=Anterior/Ventral Horn,SC.VH
FG=Fastigual Nucleus,LRC.HT.CR.FG
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
MRF=Medullary Reticular Formation,HL.RF
PRF=Pontine Reticular Formation,HT.RF
RD=Red Nucleus,LLC.MM.RD
VB=Vestibular Nuclei,LPC.HT.VBN