BrainRegionLAC FD HT PV

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Paraventricular Nucleus

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This page covers biological details of component Paraventricular Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> Paraventricular Nucleus (LAC.FD.HT.PV) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Autonomous Control Area
  • Role: processor.autonomic
  • Function: Regulate appetite and autonomic functions

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Components

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Component items:

  • Paraventricular Nucleus of Hypothalamus Magnocellular Division
    • Paraventricular Nucleus of Hypothalamus Magnocellular Division - Anterior Magnocellular Part
    • Paraventricular Nucleus of Hypothalamus Magnocellular Division - Medial Magnocellular Part
    • Paraventricular Nucleus of Hypothalamus Magnocellular Division - Posterior Magnocellular Part
      • Paraventricular Nucleus of Hypothalamus Magnocellular Division - Posterior Magnocellular Part Lateral Zone
      • Paraventricular Nucleus of Hypothalamus Magnocellular Division - Posterior Magnocellular Part Medial Zone
  • Paraventricular Nucleus of Hypothalamus Parvicellular Division
  • Paraventricular Nucleus of Hypothalamus Descending Division
    • Paraventricular Nucleus of Hypothalamus Descending Division - Dorsal Parvicellular Part
    • Paraventricular Nucleus of Hypothalamus Descending Division - Forniceal Part
    • Paraventricular Nucleus of Hypothalamus Descending Division - Lateral Parvicellular Part
    • Paraventricular Nucleus of Hypothalamus Descending Division - Medial Parvicellular Part, Ventral Zone

Connectivity

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LAC.FD.HT.PV.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.AM.MPD Medial Posterior Dorsal Amygdaloid Nucleus inhibitory-gaba Amygdalar disruption of prefrontal cortex (AM -> HT.PV, abstract)
FMM FMM.FT.HF.SUBD Distal Subiculum excitatory-glu (unknown reference)
LAC LAC.FD.HT.AR Arcuate Nucleus of Hypothalamus excitatory-glu Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> PA)
LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus excitatory-glu Eating and sleeping to survive (DMH -> PVH)
LAC.FD.HT.LTN Lateral Hypothalamic Nucleus excitatory-glu Schematic of hypothalamic circuitry underlying satiety (LHA -> PVN)
LAC.FD.HT.MPO Median Preoptic Nucleus excitatory-glu Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA)
LAC.FD.HT.SCN Suprachiasmatic Nucleus excitatory-glu Food-entrainable circadian oscillator (SCN -> PVH)
LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus excitatory-glu Glucose-sensing neural network (VMH -> PVH)
LMC LMC.MM.VTA Ventral Tegmental Area modulatory-da Physiology and pathophysiology of lower urinary tract (VTA -> PVN)
LPC LPC.HL.SOL Solitary Nucleus excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
LAC LAC.SC.CC.DCN Dorsal Commissural Nucleus excitatory-glu (unknown reference)
LAC.SC.IZ.CSC Ciliospinal Center excitatory-glu Effect of light on pupil diameter (PVN -> IML)
LAC.SC.IZ.SPS Sacral Parasympathetic Nucleus excitatory-glu (unknown reference)
LAC.SC.LH.LSN Lateral Spinal Nucleus excitatory-glu (unknown reference)
LMC LMC.HL.RP.MG Raphe Magnus Nucleus excitatory-glu (unknown reference)
LPC LPC.SC.VH.ONF Onuf's Nucleus excitatory-glu (unknown reference)
NDM NDM.NC.AL.ROFCS Sulcal Rostral Orbitofrontal Cortex excitatory-glu Bowels control brain: gut hormones and obesity (PVN -> OFC, abstract)
TEA TARGET.TEA.ENDOCRINE Endocrine Glands endocrine-neurohypophysis-oxytocin Amygdalar disruption of prefrontal cortex (HT.PV -> PUT)

Thirdparty Circuits

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ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
NTS=Solitary Nucleus,LPC.HL.SOL
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
EW=Edinger-Westphal Nucleus,LAC.MM.EWN
EYE=Eye,TARGET.TSA.EYE
GC=Ciliary Ganglion,LAC.PN.PSYM.CLG
IML=Ciliospinal Center,LAC.SC.IZ.CSC
LC=Locus Coeruleus,LMC.HT.LC
OPN=Pretectal Olivary Nucleus,LRC.MM.PT.PON
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
RET=Retinal Nucleus,LPC.FD.RT
SCG=Superior Cervical Ganglion,LAC.PN.SYM.SCG
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN

AMY=Amygdala,FAM.FT.AM
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia)
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ME=Endocrine Glands,TARGET.TEA.ENDOCRINE
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
NTS=Solitary Nucleus,LPC.HL.SOL
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
VTA=Ventral Tegmental Area,LMC.MM.VTA

ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV
INS=Insular Cortex,NC.INS
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE
SOL=Solitary Nucleus,LPC.HL.SOL
TH=Thalamus,FD.TH

ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
NTS=Solitary Nucleus,LPC.HL.SOL
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN

ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
DVM=Vagus Nucleus,LAC.HL.VGN
IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG
IML=Intermediolateral Nucleus,LAC.SC.IZ.IML
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
NBM=Basal Nucleus of Meynert,LMC.FT.NBM
ONF=Onuf's Nucleus,LPC.SC.VH.ONF
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG
PU=Dorsal Putamen Lateral,FEC.FT.PU.LT
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS
VTA=Ventral Tegmental Area,LMC.MM.VTA
ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI

AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
PA=Paraventricular Nucleus,LAC.FD.HT.PV
SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
SON=Supraoptic Nucleus,LAC.FD.HT.SO
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM


References

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