BrainRegionFMM FT HC DG

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Dentate Gyrus

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This page covers biological details of component Dentate Gyrus. Region is part of aHuman target integrated biological model.

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Components

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Connectivity

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FMM.FT.HC.DG.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FMM FMM.NC.PH.LEC Lateral Entorhinal Cortex excitatory-glu Neuronal projections in the hippocampus (ET -> DG, abstract)
FMM.NC.PH.MEC Medial Entorhinal Cortex excitatory-glu Neuronal projections in the hippocampus (ET -> DG, abstract)
FMM.NC.PH.PER Perirhinal Cortex excitatory-glu Gustatory sensory system of rat and macaque (PrC -> HF, abstract)
LAC LAC.FD.HT.PN Posterior Hypothalamic Nucleus excitatory-glu (unknown reference)
LAC.FD.HT.SUM Supramammillary Nucleus excitatory-glu Medial mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)
LRC LRC.HT.NSC Nucleus Subceruleus excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FMM FMM.FT.HC.CA3D Distal CA3 of Hippocampus excitatory-glu Neuronal projections in the hippocampus (DG -> CA3, abstract)
FMM.FT.HC.CA3M Middle CA3 of Hippocampus excitatory-glu Neuronal projections in the hippocampus (DG -> CA3, abstract)
FMM.FT.HC.CA3P Proximal CA3 of Hippocampus excitatory-glu Neuronal projections in the hippocampus (DG -> CA3, abstract)

Thirdparty Circuits

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AD=Anterodorsal Nucleus,FMM.FD.TH.AD
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LHAB=Habenula,FAM.FD.HB
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN
NPRP=Prepositus Nucleus,LRC.HL.NPH
PC=Parietal Lobe,NC.LOBE.PAR
PRHC=Postrhinal Cortex,FMM.NC.PH.POR
PSUB=Postsubiculum,FMM.NC.PH.POS
RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC
SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG
VC=Occipital Lobe,NC.LOBE.OCC

AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CG=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT=Hypothalamus,FD.HT

BLA=Basolateral Nuclear Complex,FAM.FT.AM.BL (see Amygdala)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
ET=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)

Amyg=Amygdala,FAM.FT.AM
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
mPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)

ACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PPTG=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA

AON=Anterior Olfactory Nucleus,LPC.FT.AON
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA2=Dorsolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA2
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PC=Piriform Cortex,NSA.NC.PH.PIR

ATN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
LDN=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LMam=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
PoS=Postsubiculum,FMM.NC.PH.POS
Rsp=Retrosplenial Cortex,NCP.NC.MPL.RSC
Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)

CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA2=Dorsolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA2
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
CA4=Dentate Gyrus,FMM.FT.HC.DG

AM=Amygdala,FAM.FT.AM
AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
DG=Dentate Gyrus,FMM.FT.HC.DG
DorsalCingulate=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
PosteriorCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
VentralCingulate=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG

CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA2=Dorsolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA2
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
ENT=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PRES=Presubiculum,FMM.NC.PH.PRS
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)

AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
MBIN=Medial Mammillary Nucleus,FMM.FD.MB.MMB
MBOUT=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PERI=Perirhinal Cortex,FMM.NC.PH.PER
PRESUB=Presubiculum,FMM.NC.PH.PRS
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)


References

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