BrainRegionFMM NC PH PRS

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Presubiculum

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This page covers biological details of component Presubiculum. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> Retrosubicular Area (FMM.NC.PHA.RS) -> Presubiculum (FMM.NC.PH.PRS) (see Mind Maps)
  • Type: cortex
  • Quality: L0
  • Brain area: Forebrain - Memory Management Area (FMM)
  • Area circuit: Theta Waves Control (MMATHETA)
  • Brodmann ID: 27
  • Role: cortex.orienting
  • Function: Path integration, head direction
  • Comments: close to Subicular Complex
  • Notes to function:
    • Major projects to ET, from TH.LD

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Components

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  • no child items defined

Connectivity

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FMM.NC.PH.PRS.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu uncertain Detailed amygdalohippocampal projections (Bpc -> PrS)
FMM FMM.FD.TH.AV Anteroventral Nucleus excitatory-glu uncertain (unknown reference)
FMM.FT.HF.SUBD Distal Subiculum excitatory-glu uncertain Attractor Network in Hippocampus (SUB -> PRESUB, abstract)
NCP NCP.NC.INS.PPC Peripaleocortical Claustral feedforward-glu uncertain (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FMM FMM.FD.MB.LMB Lateral Mammillary Nucleus excitatory-glu uncertain Mammillary bodies: two memory systems in one (PRS -> LMB)
FMM.FD.MB.MMB Medial Mammillary Nucleus excitatory-glu uncertain Attractor Network in Hippocampus (PRESUB -> MBIN)
FMM.FD.TH.LD Lateral Dorsal Nucleus of Thalamus excitatory-glu uncertain Contributions of Diencephalon to Recognition Memory (Presub -> LD)
FMM.NC.PH.MEC Medial Entorhinal Cortex feedforward-glu uncertain Attractor Network in Hippocampus (PRESUB -> EC, abstract)
NPE NPE.FD.TH.MPV Medial Pulvinar excitatory-glu uncertain Contributions of Diencephalon to Recognition Memory (Presub -> mPULV)

Thirdparty Circuits

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AD=Anterodorsal Nucleus,FMM.FD.TH.AD
AM=Anteromedial Nucleus,NCP.FD.TH.AM
AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
AV=Anteroventral Nucleus,FMM.FD.TH.AV
CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM
DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
MDmc=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MID=Midline Nuclear Group of Thalamus,FD.TH.MTH (see Cognitive Thalamus)
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
Parasub=Parasubiculum,FMM.NC.PH.PAS
Perirhinal=Perirhinal Cortex,FMM.NC.PH.PER
PostCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
Presub=Presubiculum,FMM.NC.PH.PRS
Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
SubPrePara=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
mPULV=Medial Pulvinar,NPE.FD.TH.MPV

ADTH=Anterodorsal Nucleus,FMM.FD.TH.AD
AMTH=Anteromedial Nucleus,NCP.FD.TH.AM
AVTH=Anteroventral Nucleus,FMM.FD.TH.AV
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PAS=Parasubiculum,FMM.NC.PH.PAS
POS=Postsubiculum,FMM.NC.PH.POS
PRS=Presubiculum,FMM.NC.PH.PRS
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
SupraMM=Supramammillary Nucleus,LAC.FD.HT.SUM
TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see Hypothalamus)
VTN=Ventral Tegmental Area,LMC.MM.VTA

AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
MBIN=Medial Mammillary Nucleus,FMM.FD.MB.MMB
MBOUT=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PERI=Perirhinal Cortex,FMM.NC.PH.PER
PRESUB=Presubiculum,FMM.NC.PH.PRS
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)

CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA2=Dorsolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA2
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
ENT=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PRES=Presubiculum,FMM.NC.PH.PRS
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)

ABmg=Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB
Bmg=Magnocellular Basal Amygdaloid Nucleus,FAM.FT.AM.BM
Bpc=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP
CA1D=Distal CA1 of Hippocampus,FMM.FT.HC.CA1D
CA1P=Proximal CA1 of Hippocampus,FMM.FT.HC.CA1P
L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
PaS=Parasubiculum,FMM.NC.PH.PAS
PrS=Presubiculum,FMM.NC.PH.PRS


References

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