BrainRegionFAM FD MHB

Medial Habenula

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This page covers biological details of component Medial Habenula. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Diencephalon -> Habenula (FAM.FD.HB) -> Medial Habenula (FAM.FD.MHB) (see Mind Maps)
• Type: nucleus
• Brain area: Forebrain - Affective Motivations Area
• Role: relay
• Function: Encoding negative feedback, indirect
• Notes to function: affects VTA, dorsal raphe but via interpeduncular nucleus

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.SEP.BAC	Bed Nucleus of Anterior Commissure	excitatory-glu	Habenula Connections (S -> MHb, abstract)
	FAM.FT.SEP.SF	Septofimbrial Nucleus	inhibitory-gaba	Habenula Connections (S -> MHb, abstract)
	FAM.FT.SEP.TR	Triangular Septal Nucleus	inhibitory-gaba	Habenula Connections (S -> MHb, abstract)
LMC	LMC.HP.LC	Locus Coeruleus	modulatory-ne	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FD.LHB.MED	Lateral Habenula Medial Part	excitatory-glu	(unknown reference)
	FAM.HP.PPN.IPD	Interpeduncular Nucleus	excitatory-glu	Habenula Connections (MHb -> IP)
TEA	TARGET.TEA.ENDOCRINE	Endocrine Glands	endocrine-pineal-gland	Habenula Connections (MHb -> PB)

Thirdparty Circuits

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• Exploring role of habenula in emotional behaviors - see Reference

• Control dopaminergic and serotonergic systems - see Reference

• Habenula Connections - see Reference

• Connectivity of dorsal diencephalic conduction system - see Reference

References

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• http://dgr.brain.riken.jp/AsymmetryE.html
• http://www.nature.com/neuro/journal/v17/n9/full/nn.3779.html
• http://www.scholarpedia.org/article/Habenula
• http://rstb.royalsocietypublishing.org/content/364/1519/1005