BrainRegionLAC FD HT PRM

Premammillary Nucleus

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This page covers biological details of component Premammillary Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Lateral Hypothalamic Area (LAC.FD.HT.LT) -> Lateral Tuberal Nuclei (LAC.FD.HT.LTUB) -> Premammillary Nucleus (LAC.FD.HT.PRM) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Autonomous Control Area
• Role: relay
• Function: expression of fear responses to environmental threats
• Notes to function: integrate information involved in spatial working memory, which may result in attentional mechanisms on selection of appropriate escape strategies

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Components

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Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.AM.MPV	Medial Posterior Ventral Amygdaloid Nucleus	inhibitory-gaba	Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)
LAC	LAC.FD.HT.AH	Anterior Hypothalamic Nucleus	excitatory-glu	(unknown reference)
LMC	LMC.MM.VTA	Ventral Tegmental Area	modulatory-da	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LAC	LAC.FD.HT.MPO	Median Preoptic Nucleus	excitatory-glu	(unknown reference)
	LAC.FD.HT.VM	Ventromedial Hypothalamic Nucleus	excitatory-glu	(unknown reference)

Thirdparty Circuits

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References

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