Substantia Nigra Pars Compacta Medial

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This page covers biological details of component Substantia Nigra Pars Compacta Medial. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Execution Control Area
Role: relay
Function: motivational loop
Notes to function: VP, ventral circuits

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Components

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Connectivity

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FEC.FT.SNC.MED.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.BNST	Bed Nucleus of Stria Terminalis	excitatory-glu	(unknown reference)
FEC	FEC.FT.ACC.CORE	Nucleus Accumbens Core	inhibitory-gaba	(unknown reference)
	FEC.FT.GPI.RM	Globus Pallidus Internal Rostromedial	inhibitory-gaba	Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)
	FEC.FT.SNR.MED	Substantia Nigra Pars Reticulata Medial	inhibitory-gaba	(unknown reference)
	FEC.HT.PPN.RMTG	Rostromedial Tegmental Nucleus	inhibitory-gaba	Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> SNc, abstract)
LMC	LMC.HT.LC	Locus Coeruleus	modulatory-ne	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FT.AM.CEM	Medial Central Amygdaloid Nucleus	modulatory-da	(unknown reference)
FEC	FEC.FT.ACC.SH	Nucleus Accumbens Shell	modulatory-da	Connectivity map of the habenula (SNc -> CPu, abstract)
LAC	LAC.FD.HT.SUM	Supramammillary Nucleus	modulatory-da	(unknown reference)
LRC	LRC.HT.PRF.PVR	Parvocellular Reticular Nucleus	modulatory-da	(unknown reference)

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