BrainRegionFEC FT SNC MED
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Substantia Nigra Pars Compacta Medial
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This page covers biological details of component Substantia Nigra Pars Compacta Medial. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED) (see Mind Maps)
- Type: nucleus
- Brain area: Forebrain - Execution Control Area
- Role: relay
- Function: motivational loop
- Notes to function: VP, ventral circuits
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FT.BNST | Bed Nucleus of Stria Terminalis | excitatory-glu | (unknown reference) |
| FEC | FEC.FT.ACC.CORE | Nucleus Accumbens Core | inhibitory-gaba | (unknown reference) |
| FEC.FT.GPI.RM | Globus Pallidus Internal Rostromedial | inhibitory-gaba | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
| FEC.FT.SNR.MED | Substantia Nigra Pars Reticulata Medial | inhibitory-gaba | (unknown reference) | |
| FEC.HT.PPN.RMTG | Rostromedial Tegmental Nucleus | inhibitory-gaba | Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> SNc, abstract) | |
| LMC | LMC.HT.LC | Locus Coeruleus | modulatory-ne | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FAM | FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | modulatory-da | (unknown reference) |
| FEC | FEC.FT.ACC.SH | Nucleus Accumbens Shell | modulatory-da | Connectivity map of the habenula (SNc -> CPu, abstract) |
| LAC | LAC.FD.HT.SUM | Supramammillary Nucleus | modulatory-da | (unknown reference) |
| LRC | LRC.HT.PRF.PVR | Parvocellular Reticular Nucleus | modulatory-da | (unknown reference) |
Thirdparty Circuits
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- Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey - see Reference
References
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