BrainRegionFMM FT HC DG

Dentate Gyrus

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This page covers biological details of component Dentate Gyrus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Telencephalon -> Hippocampal Formation (HBA.FT.HF) -> Hippocampus (HBA.FT.HC) -> Dentate Gyrus (FMM.FT.HC.DG) (see Mind Maps)
• Type: cortex
• Brain area: Forebrain - Memory Management Area
• Role: processor
• Function: Distinguishing multiple instances of similar events

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Components

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• no child items defined

Connectivity

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• Inbound Region Connections:*

|| Source Area || Source Region || Source Name || Type || Reference || || FMM || FMM.NC.PH.LEC || Lateral Entorhinal Cortex || excitatory-glu || [projections in the hippocampus (ET -> DG, abstract)] || || || FMM.NC.PH.MEC || Medial Entorhinal Cortex || excitatory-glu || [projections in the hippocampus (ET -> DG, abstract)] || || || FMM.NC.PH.PER || Perirhinal Cortex || excitatory-glu || [sensory system of rat and macaque (PrC -> HF, abstract)] || || LAC || LAC.FD.HT.PN || Posterior Hypothalamic Nucleus || excitatory-glu || (unknown reference) || || || LAC.FD.HT.SUM || Supramammillary Nucleus || excitatory-glu || [mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)] || || LRC || LRC.HP.PN.SC || Nucleus Subceruleus || excitatory-glu || (unknown reference) ||

• Outbound Region Connections:*

|| Target Area || Target Region || Target Name || Type || Reference || || FMM || FMM.FT.HC.CA3D || Distal CA1 of Hippocampus || excitatory-glu || [projections in the hippocampus (DG -> CA3, abstract)] || || || FMM.FT.HC.CA3M || Middle CA1 of Hippocampus || excitatory-glu || [projections in the hippocampus (DG -> CA3, abstract)] || || || FMM.FT.HC.CA3P || Proximal CA1 of Hippocampus || excitatory-glu || [projections in the hippocampus (DG -> CA3, abstract)] ||

Thirdparty Circuits

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• [model of hippocampal formation anatomy] - see [[1]]

• [Novelty, Motivational Salience, and Reward to Control Attention and Learning] - see [[2]]

• [model of cortico-hippocampal formation with subcortical projections for motor actions] - see [[3]]

• [Formation] - see Reference

• [in Detail] - see [[4]]

• [Connections of Hippocampus] - see [[5]]

• [of impulses in hippocampal region] - see [[6]]

• [Network in Hippocampus] - see [[7]]

• [projections in the hippocampus] - see [[8]]

References

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• http://www.sciencedirect.com/science/article/pii/S030100820900183X
• http://www.impulsecontroldisorders.org/html/cravings.html
• http://www.sciencedirect.com/science/article/pii/S1571064507000243
• article:2009-Hippocampus-Thesis.pdf
• http://what-when-how.com/neuroscience/the-limbic-system-integrative-systems-part-1/
• http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html
• http://www.sciencedirect.com/science/article/pii/S030645220600755X
• http://learnmem.cshlp.org/content/14/11/714/F1.expansion
• http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full