BrainRegionLPC HL AMB

Ambiguus Nucleus

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This page covers biological details of component Ambiguus Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Hindbrain Myelencephalon -> Myelencephalic Motor Nuclei (HL.MN) -> Expiratory Center (HL.RC) -> Ambiguus Nucleus (LPC.HL.AMB) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Peripheral Control Area
• Role: relay
• Function: Control muscles of the soft palate, pharynx, and larnyx
• Notes to function: On par with VGM, speech; speech and swallowing

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LMC	LMC.MM.PAG	Periaqueductal Gray Matter	modulatory-enk	(unknown reference)
LPC	LPC.HL.SOL	Solitary Nucleus	excitatory-glu	(unknown reference)
LRC	LRC.HL.RA	Retroambigualis Nucleus	excitatory-glu	(unknown reference)
	LRC.HT.PRF.CRF	Caudal Pontine Reticular Nucleus	excitatory-glu	Vocal Control (RF -> NucleusAmbiguus, abstract)
NMA	NMA.NC.MC	Motor Cortex	excitatory-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
TEA	TARGET.TEA.FEEDER	Mouth feeder	inferior-pharyngeal-constrictor-muscle	(unknown reference)
	TARGET.TEA.LUNG	Lung	stylopharyngeus-muscle	(unknown reference)
	TARGET.TEA.SPEAKER	Mouth speaker	arytenoid-muscle	(unknown reference)
TSA	TARGET.TSA.NOSE	Nose	nose-salpingopharyngeus	(unknown reference)

Thirdparty Circuits

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• Vocal Control - see Reference

References

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• http://www.frontiersin.org/neuroanatomy/10.3389/fnana.2011.00034/full