Revision as of 01:19, 16 June 2015

Medial Entorhinal Cortex

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This page covers biological details of component Medial Entorhinal Cortex. Region is part of aHuman target integrated biological model.

• *Top-down path to region*: Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> Rhinal Cortex (NC.PHA.RH) -> Entorhinal Cortex (FMM.NC.PH.ET) -> Medial Entorhinal Cortex (FMM.NC.PH.MEC) (see Mind Maps)
• *Type*: cortex
• *Brain area*: Forebrain - Memory Management Area
• *Brodmann ID*: 28
• *Role*: processor
• *Function*: Memory consolidation, basic, view inpedepdent position
• *Notes to function*: spatial input to HC; grid cells; path integration computations based on a global frame of reference, primarily using internally generated, self-motion cues and external input about environmental boundaries and scenes; provides hippocampus with coordinate system that underlies spatial context of experience

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Components

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Connectivity

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• Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* || || FMM || BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD || Distal Subiculum || excitatory-glu || [Attractor Network in Hippocampus (SUB -> EC, abstract)] || || || FMM.NC.PH.PAS || Parasubiculum || feedforward-glu || (unknown reference) || || || FMM.NC.PH.POR || Postrhinal Cortex || feedforward-glu || [Entorhinal Cortex Inputs and Outputs (TFTH -> EC, abstract)] || || || FMM.NC.PH.POS || Postsubiculum || feedforward-glu || [Head Direction Cell Circuit (PSUB -> EC, abstract)] || || || FMM.NC.PH.PRS || Presubiculum || feedforward-glu || [Attractor Network in Hippocampus (PRESUB -> EC, abstract)] || || NCP || BrainRegionNCP_NC_MPL_PSCG NCP.NC.MPL.PSCG || Posterior Cingulate Cortex || feedforward-glu || [McNaughton Spatial Processing Network (PCGRSP -> EnthCortex, abstract)] || || || NCP.NC.MPL.RSC || Retrosplenial Cortex || feedforward-glu || [McNaughton Spatial Processing Network (PCGRSP -> EnthCortex, abstract)] ||

• Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* || || FMM || BrainRegionFMM_FD_MB_MMB FMM.FD.MB.MMB || Medial Mammillary Nucleus || excitatory-glu || [Mammillary bodies: two memory systems in one (MedialEC -> MMB, abstract)] || || || FMM.FD.TH.LD || Lateral Dorsal Nucleus of Thalamus || excitatory-glu || [Contributions of Diencephalon to Recognition Memory (EC -> LD, abstract)] || || || FMM.FT.HC.CA1P || Proximal CA1 of Hippocampus || excitatory-glu || [Neuronal projections in the hippocampus (ET -> CA1, abstract)] || || || FMM.FT.HC.CA2 || Dorsolateral Cornu Ammonis of Hippocampus || excitatory-glu || [Amygdala and its network (EC -> HC, abstract)] || || || FMM.FT.HC.DG || Dentate Gyrus || excitatory-glu || [Neuronal projections in the hippocampus (ET -> DG, abstract)] ||

Thirdparty Circuits

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References

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