Difference between revisions of "BrainRegionLMC MM PAG"
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Periaqueductal Gray Matter
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This page covers biological details of component Periaqueductal Gray Matter. Region is part of aHuman target integrated biological model.
- *Top-down path to region*: Midbrain Mesencephalon -> Periaqueductal Gray Matter (LMC.MM.PAG) (see Mind Maps)
- *Type*: nucleus
- *Brain area*: Lower Brain - Modulatory Contol Area
- *Role*: relay
- *Function*: Descending modulation of pain and in defensive behaviour
- *Notes to function*: if there is a lesion in the PAG, then consciousness is lost; electrical stimulation of the PAG results in immediate and profound analgesia; modulatory nucleus
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Components
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- no child items defined
Connectivity
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- Inbound Region Connections:*
|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* || || FAM || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || excitatory-glu || [Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)] || || LAC || BrainRegionLAC_FD_HT_VM LAC.FD.HT.VM || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference) || || NCP || BrainRegionNCP_NC_AL_SGCG NCP.NC.AL.SGCG || Subgenual Cingulate Cortex || excitatory-glu || (unknown reference) ||
- Outbound Region Connections:*
|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* || || LAC || BrainRegionLAC_HP_BR LAC.HP.BR || Barrington's Nucleus || modulatory-enk || [Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)] || || LLC || BrainRegionLLC_FD_TH_SF LLC.FD.TH.SF || Subfascicular Nucleus of Thalamus || modulatory-enk || (unknown reference) || || LMC || BrainRegionLMC_HM_RP_MG LMC.HM.RP.MG || Raphe Magnus Nucleus || modulatory-enk || (unknown reference) || || || LMC.HM.RP.PL || Raphe Pallidus Nucleus || modulatory-enk || (unknown reference) || || LPC || BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || modulatory-enk || (unknown reference) || || || LPC.HM.AMB || Ambiguus Nucleus || modulatory-enk || (unknown reference) || || LRC || BrainRegionLRC_HM_RA LRC.HM.RA || Retroambigualis Nucleus || modulatory-enk || (unknown reference) || || || LRC.HP.PN.SC || Nucleus Subceruleus || modulatory-enk || (unknown reference) ||
Thirdparty Circuits
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- [and its network] - see [Reference]
- [disruption of prefrontal cortex] - see [Reference]
References
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- http://jp.physoc.org/content/557/1/287/F9.expansion.html
- http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0
- http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
- http://neuropolitics.org/defaultmay10.asp
