Difference between revisions of "BrainRegionLMC MM PAG"
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− | <pre style="color: green">Periaqueductal Gray Matter | + | <pre style="color: green">Periaqueductal Gray Matter</pre> |
− | </pre> | + | |
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_MM_PAG]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_MM_PAG]] | ||
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Region is part of aHuman target integrated biological model. | Region is part of aHuman target integrated biological model. | ||
− | * | + | * '''Top-down path to region''': Midbrain Mesencephalon -> Periaqueductal Gray Matter (LMC.MM.PAG) (see [[OverallMindMaps|Mind Maps]]) |
− | * | + | * '''Type''': nucleus |
− | * | + | * '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]] |
− | * | + | * '''Role''': relay |
− | * | + | * '''Function''': Descending modulation of pain and in defensive behaviour |
− | * | + | * '''Notes to function''': if there is a lesion in the PAG, then consciousness is lost; electrical stimulation of the PAG results in immediate and profound analgesia; modulatory nucleus |
(generated) | (generated) | ||
= Components = | = Components = | ||
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*Inbound Region Connections:* | *Inbound Region Connections:* | ||
− | || | + | || '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' || |
− | || [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [[http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)]] || | + | || [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [[http://neuropolitics.org/defaultmay10.asp|Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)]] || |
− | || [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference) || | + | || [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference) || |
− | || [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_AL_SGCG NCP.NC.AL.SGCG]] || Subgenual Cingulate Cortex || excitatory-glu || (unknown reference) || | + | || [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_AL_SGCG|NCP.NC.AL.SGCG]] || Subgenual Cingulate Cortex || excitatory-glu || (unknown reference) || |
*Outbound Region Connections:* | *Outbound Region Connections:* | ||
− | || | + | || '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' || |
− | || [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HP_BR LAC.HP.BR]] || Barrington's Nucleus || modulatory-enk || [[http://jp.physoc.org/content/557/1/287/F9.expansion.html Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)]] || | + | || [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HP_BR|LAC.HP.BR]] || Barrington's Nucleus || modulatory-enk || [[http://jp.physoc.org/content/557/1/287/F9.expansion.html|Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)]] || |
− | || [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_FD_TH_SF LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || modulatory-enk || (unknown reference) || | + | || [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_FD_TH_SF|LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || modulatory-enk || (unknown reference) || |
− | || [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HM_RP_MG LMC.HM.RP.MG]] || Raphe Magnus Nucleus || modulatory-enk || (unknown reference) || | + | || [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]] || Raphe Magnus Nucleus || modulatory-enk || (unknown reference) || |
|| || [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]] || Raphe Pallidus Nucleus || modulatory-enk || (unknown reference) || | || || [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]] || Raphe Pallidus Nucleus || modulatory-enk || (unknown reference) || | ||
− | || [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || modulatory-enk || (unknown reference) || | + | || [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_FD_TH_PV|LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || modulatory-enk || (unknown reference) || |
|| || [[BrainRegionLPC_HM_AMB|LPC.HM.AMB]] || Ambiguus Nucleus || modulatory-enk || (unknown reference) || | || || [[BrainRegionLPC_HM_AMB|LPC.HM.AMB]] || Ambiguus Nucleus || modulatory-enk || (unknown reference) || | ||
− | || [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HM_RA LRC.HM.RA]] || Retroambigualis Nucleus || modulatory-enk || (unknown reference) || | + | || [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HM_RA|LRC.HM.RA]] || Retroambigualis Nucleus || modulatory-enk || (unknown reference) || |
|| || [[BrainRegionLRC_HP_PN_SC|LRC.HP.PN.SC]] || Nucleus Subceruleus || modulatory-enk || (unknown reference) || | || || [[BrainRegionLRC_HP_PN_SC|LRC.HP.PN.SC]] || Nucleus Subceruleus || modulatory-enk || (unknown reference) || | ||
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(generated) | (generated) | ||
− | * [[http://jp.physoc.org/content/557/1/287/F9.large.jpg|Schematic overview of spinobulbospinal micturition reflex pathway]] - see [[http://jp.physoc.org/content/557/1/287/F9.expansion.html Reference]] | + | * [[http://jp.physoc.org/content/557/1/287/F9.large.jpg|Schematic overview of spinobulbospinal micturition reflex pathway]] - see [[http://jp.physoc.org/content/557/1/287/F9.expansion.html|Reference]] |
<img src="http://jp.physoc.org/content/557/1/287/F9.large.jpg" alt="unavailable"> | <img src="http://jp.physoc.org/content/557/1/287/F9.large.jpg" alt="unavailable"> | ||
− | * [[http://www.springerimages.com/img/Images/Springer/JOU=10194/VOL=2006.7/ISU=4/ART=2006_307/MediaObjects/MEDIUM_10194_2006_Article_307_Fig1.jpg|Pain matrix]] - see [[http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0 Reference]] | + | * [[http://www.springerimages.com/img/Images/Springer/JOU=10194/VOL=2006.7/ISU=4/ART=2006_307/MediaObjects/MEDIUM_10194_2006_Article_307_Fig1.jpg|Pain matrix]] - see [[http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0|Reference]] |
<img src="http://www.springerimages.com/img/Images/Springer/JOU=10194/VOL=2006.7/ISU=4/ART=2006_307/MediaObjects/MEDIUM_10194_2006_Article_307_Fig1.jpg" alt="unavailable"> | <img src="http://www.springerimages.com/img/Images/Springer/JOU=10194/VOL=2006.7/ISU=4/ART=2006_307/MediaObjects/MEDIUM_10194_2006_Article_307_Fig1.jpg" alt="unavailable"> | ||
− | * [[http://www.surgicalneurologyint.com/articles/2012/3/2/images/SurgNeurolInt_2012_3_2_40_91609_u1.jpg|Amygdala and its network]] - see [[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Reference]] | + | * [[http://www.surgicalneurologyint.com/articles/2012/3/2/images/SurgNeurolInt_2012_3_2_40_91609_u1.jpg|Amygdala and its network]] - see [[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin|Reference]] |
<img src="http://www.surgicalneurologyint.com/articles/2012/3/2/images/SurgNeurolInt_2012_3_2_40_91609_u1.jpg" alt="unavailable"> | <img src="http://www.surgicalneurologyint.com/articles/2012/3/2/images/SurgNeurolInt_2012_3_2_40_91609_u1.jpg" alt="unavailable"> | ||
− | * [[http://neuropolitics.org/connect-amygdala.jpg|Amygdalar disruption of prefrontal cortex]] - see [[http://neuropolitics.org/defaultmay10.asp Reference]] | + | * [[http://neuropolitics.org/connect-amygdala.jpg|Amygdalar disruption of prefrontal cortex]] - see [[http://neuropolitics.org/defaultmay10.asp|Reference]] |
<img src="http://neuropolitics.org/connect-amygdala.jpg" alt="unavailable"> | <img src="http://neuropolitics.org/connect-amygdala.jpg" alt="unavailable"> |
Revision as of 10:43, 16 June 2015
Periaqueductal Gray Matter
@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_MM_PAG
This page covers biological details of component Periaqueductal Gray Matter. Region is part of aHuman target integrated biological model.
- Top-down path to region: Midbrain Mesencephalon -> Periaqueductal Gray Matter (LMC.MM.PAG) (see Mind Maps)
- Type: nucleus
- Brain area: Lower Brain - Modulatory Contol Area
- Role: relay
- Function: Descending modulation of pain and in defensive behaviour
- Notes to function: if there is a lesion in the PAG, then consciousness is lost; electrical stimulation of the PAG results in immediate and profound analgesia; modulatory nucleus
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
- Inbound Region Connections:*
|| Source Area || Source Region || Source Name || Type || Reference || || FAM || FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || excitatory-glu || [disruption of prefrontal cortex (AM -> PAG, abstract)] || || LAC || LAC.FD.HT.VM || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference) || || NCP || NCP.NC.AL.SGCG || Subgenual Cingulate Cortex || excitatory-glu || (unknown reference) ||
- Outbound Region Connections:*
|| Target Area || Target Region || Target Name || Type || Reference || || LAC || LAC.HP.BR || Barrington's Nucleus || modulatory-enk || [overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)] || || LLC || LLC.FD.TH.SF || Subfascicular Nucleus of Thalamus || modulatory-enk || (unknown reference) || || LMC || LMC.HM.RP.MG || Raphe Magnus Nucleus || modulatory-enk || (unknown reference) || || || LMC.HM.RP.PL || Raphe Pallidus Nucleus || modulatory-enk || (unknown reference) || || LPC || LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || modulatory-enk || (unknown reference) || || || LPC.HM.AMB || Ambiguus Nucleus || modulatory-enk || (unknown reference) || || LRC || LRC.HM.RA || Retroambigualis Nucleus || modulatory-enk || (unknown reference) || || || LRC.HP.PN.SC || Nucleus Subceruleus || modulatory-enk || (unknown reference) ||
Thirdparty Circuits
(generated)
- [and its network] - see [[3]]
- [disruption of prefrontal cortex] - see [[4]]
References
(generated)
- http://jp.physoc.org/content/557/1/287/F9.expansion.html
- http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0
- http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
- http://neuropolitics.org/defaultmay10.asp