BrainRegionNCP FD TH VPI

Ventral Posteroinferior Nucleus

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This page covers biological details of component Ventral Posteroinferior Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Diencephalon -> Thalamus (FD.TH) -> Sensory Thalamus (FD.TH.SR) -> Ventral Posterior Nuclei (NSA.FD.TH.VP) -> Ventral Posteroinferior Nucleus (NCP.FD.TH.VPI) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Neocortical Brain - Conscious Personality Area
• Role: thalamic.sensory.primary
• Function: Relays pain and temperature from body to insula

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LPC	LPC.HT.PRF.PB	Parabrachial Nucleus	excitatory-glu	(unknown reference)
	LPC.SC.PH.LMG	Lower Marginal Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	LPC.SC.PH.LSG	Lower Substantia Gelatinosa	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	LPC.SC.PH.UMG	Upper Marginal Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	LPC.SC.PH.USG	Upper Substantia Gelatinosa	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
NCP	NCP.NC.INS.PIC	Posterior Insular Cortex	excitatory-glu	Pain matrix (TH.VPI -> INS)
	NCP.NC.PG.PV	Parietal Ventral Cortex	excitatory-glu	(unknown reference)
	NCP.NC.PG.S2	Secondary Somatosensory Cortex	excitatory-glu	Afferent pain pathways (Thalamus -> S2, abstract)

Thirdparty Circuits

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• Pain matrix - see Reference (CF.SOMATOSENSORY-THALAMUS)

INS=Posterior Insular Cortex,NCP.NC.INS.PIC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
TH.VPI=Ventral Posteroinferior Nucleus,NCP.FD.TH.VPI
TH.VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
TH.VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM

• Afferent pain pathways - see Reference (CF.PAIN-PATH)

ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AMY=Amygdala,FAM.FT.AM
BG=Basal Ganglia,FEC.FT.BG
Cerebellum=Cerebellar Complex,LLC.HT.CRC
Insula=Insular Cortex,NC.INS
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PFC=Prefrontal Cortex,NC.AL.PFC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2
SC=Posterior/Dorsal Horn,BMA.SC.PH
Thalamus=Sensory Thalamus,FD.TH.SR

References

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• http://users.atw.hu/blp6/BLP6/HTML/C0079780323045827.htm
• http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html