Laterodorsal Tegmental Nucleus

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This page covers biological details of component Laterodorsal Tegmental Nucleus. Region is part of aHuman target integrated biological model.

Top-down path to region: Hindbrain Metencephalon -> Pontine Tegmental Nuclei (HT.TG) -> Laterodorsal Tegmental Nucleus (LMC.HT.TG.LDT) (see Mind Maps)
Type: nucleus
Brain area: Lower Brain - Modulatory Contol Area
Role: processor.autonomic
Function: Modulating sustained attention or in mediating alerting responses
Notes to function: sleep, waking, motor function, learning and reward

(generated)

Components

(generated)

Component items:

Lateral Tegmental Nucleus
Dorsal Tegmental Nucleus (LMC.HT.TG.DTG): accurate landmark navigation
- Dorsal Tegmental Nucleus Pars Dorsalis
- Dorsal Tegmental Nucleus Pars Ventralis

Connectivity

(generated)

LMC.HT.TG.LDT.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FD.LHB.MED	Lateral Habenula Medial Part	excitatory-glu	Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)
FEC	FEC.HT.TG.IPD	Interpeduncular Nucleus	modulatory-ach	Head Direction Cell Circuit (IPD -> DTN)
	FEC.HT.TG.RMTG	Rostromedial Tegmental Nucleus	inhibitory-gaba	(unknown reference)
FMM	FMM.FD.MB.LMB	Lateral Mammillary Nucleus	excitatory-glu	Head Direction Cell Circuit (LMB -> DTN)
LAC	LAC.FD.HT.VLPO	Ventrolateral Preoptic Nucleus	excitatory-glu	Simplified NREM sleep-promoting pathway (VLPO -> LDTg)
LRC	LRC.HL.NPH	Prepositus Nucleus	excitatory-glu	(unknown reference)
NSA	NSA.FD.TH.SG	Suprageniculate Nucleus of Thalamus	excitatory-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.HT.TG.IPD	Interpeduncular Nucleus	modulatory-ach	(unknown reference)
FMM	FMM.FD.MB.LMB	Lateral Mammillary Nucleus	modulatory-ach	Hippocampal Formation (DTN -> LMam)
LAC	LAC.HL.SAL.ISL	Inferior Salivatory Nucleus	modulatory-ach	(unknown reference)
	LAC.HL.SAL.SSL	Superior Salivatory Nucleus	modulatory-ach	(unknown reference)
LRC	LRC.HL.NPH	Prepositus Nucleus	modulatory-ach	Head Direction Cell Circuit (DTN -> NPRP)
NSA	NSA.FD.TH.SG	Suprageniculate Nucleus of Thalamus	modulatory-ach	Head Direction Cell Circuit (DTN -> SUPGEN)