BrainRegionNPE NC SMC SEF

Supplementary Eye Field

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This page covers biological details of component Supplementary Eye Field. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Supplementary Motor Cortex (NMA.NC.SMC) -> Supplementary Eye Field (NPE.NC.SMC.SEF) (see Mind Maps)
• Type: cortex
• Brain area: Neocortical Brain - Unimodal Execution Area
• Brodmann ID: 06
• Role: cortex.generic
• Function: high level aspects of saccade control
• Notes to function: Complex spatial transformations, learned transformations, and executive cognitive functions; dorsorostral of F7

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NDM	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	feedforward-glu	3 Visual Cortex Paths (LPC -> pre-SMA, abstract)
NPE	NPE.NC.SPL.PG	Caudal Precuneus	feedforward-glu	Movement Planning (PPC -> SMC, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LRC	LRC.MM.RP.RIP	Raphe Interpositus Nucleus	excitatory-glu	Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract)
NPE	NPE.NC.PMC.AFEF	Anterior Frontal Eye Field	feedforward-glu	Summary of eye movement control (SEF -> FEF, abstract)

Thirdparty Circuits

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• Horizontal saccades and smooth pursuit movements - see Reference

• Global visual system - see Reference

• Summary of eye movement control - see Reference

• Oculomotor decision-making - see Reference

References

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• http://www.sciencedirect.com/science/article/pii/S0006899301025987
• http://www.sciencedirect.com/science/article/pii/S0959438808001566
• http://www.cixip.com/index.php/page/content/id/1190
• http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0