Medial Mediodorsal Nucleus of Thalamus

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This page covers biological details of component Medial Mediodorsal Nucleus of Thalamus. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Diencephalon -> Thalamus (FD.TH) -> Mediodorsal Nucleus of Thalamus (FD.TH.MD) -> Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM) (see Mind Maps)
Type: nucleus
Brain area: Neocortical Brain - Decision Making Area
Role: processor
Function: relay emotional attention to orbitofrontal cortex
Notes to function: orbitofrontal cortex (BA12,13) defined by MDm projection; relay AM-Bp to OFC; OFCm - subjective pleasantness, OFCl - subjective unpleasantness

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Components

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Connectivity

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NDM.FD.TH.MDM.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	excitatory-glu	Prefrontal Cortex (PFC) in emotional behavior (AM -> TH, abstract)
	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	excitatory-glu	Amygdala and its network (BLN -> MD, abstract)
	FAM.FT.SEP.MED	Medial Septal Nucleus	modulatory-ach	Thalamocortical relationships (s1MD -> MD, abstract)
FEC	FEC.FT.GPI.RM	Globus Pallidus Internal Rostromedial	inhibitory-gaba	Saccadic Vision (BG -> Thalamus, abstract)
FMM	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	excitatory-glu	Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract)
	FMM.NC.PH.PER	Perirhinal Cortex	excitatory-glu	Contributions of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
NDM	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	excitatory-glu	Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)
	NDM.NC.AL.FPC	Lateral Frontopolar Cortex	excitatory-glu	Amygdala and its network (MD -> MPFC, abstract)