BrainRegionFEC FT GPI DL

Globus Pallidus Internal Dorsolateral

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This page covers biological details of component Globus Pallidus Internal Dorsolateral. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Globus Pallidus (FEC.FT.GP) -> Dorsal Pallidum (FEC.FT.DP) -> Globus Pallidus Internal (FEC.FT.GPI) -> Globus Pallidus Internal Dorsolateral (FEC.FT.GPI.DL) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Forebrain - Execution Control Area (FEC)
• Area circuit: Oculomotor and Auditory/Association Loop (FECOM)
• Role: basal.ganglia.suppress
• Function: Oculomotor loop

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
FEC	FEC.FD.STN.ICD	Subthalamic Nucleus Internal Caudal	excitatory-glu	uncertain	Basal Ganglia Activity (STN -> GPi, abstract)
	FEC.FT.CN.BD	Caudate Nucleus Body	inhibitory-gaba	uncertain	Habenula Connections (CPu -> GPi, abstract)
	FEC.FT.GPE.DL	Globus Pallidus External Dorsolateral	inhibitory-gaba	uncertain	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
NPE	NPE.FD.TH.LP	Lateral Posterior Nucleus of Thalamus	inhibitory-gaba	uncertain	Saccadic Vision (BG -> Thalamus, abstract)

Thirdparty Circuits

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• Saccadic Vision - see Reference (CP.SACCADIC-VISION)

BG=Basal Ganglia,FEC.FT.BG
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
Thalamus=Thalamus,FD.TH
VisualCortex=Occipital Lobe,NC.LOBE.OCC

References

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• http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html