BrainRegionNDM FD TH MDM

Medial Mediodorsal Nucleus of Thalamus

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This page covers biological details of component Medial Mediodorsal Nucleus of Thalamus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Diencephalon -> Thalamus (FD.TH) -> Mediodorsal Nucleus of Thalamus (FCA.FD.TH.MD) -> Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM) (see Mind Maps)
• Type: nucleus
• Brain area: Neocortical Brain - Decision Making Area
• Role: processor
• Function: relay emotional attention to orbitofrontal cortex
• Notes to function: orbitofrontal cortex (BA12,13) defined by MDm projection; relay AM-Bp to OFC; OFCm - subjective pleasantness, OFCl - subjective unpleasantness

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Components

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Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	excitatory-glu	[Cortex (PFC) in emotional behavior (AM -> TH, abstract)]
	FAM.FT.SEP.MED	Medial Septal Nucleus	modulatory-ach	[relationships (s1MD -> MD, abstract)]
FEC	FEC.FT.GPI.RM	Globus Pallidus Internal Rostromedial	inhibitory-gaba	[Vision (BG -> Thalamus, abstract)]
FMM	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	excitatory-glu	[of Diencephalon to Recognition Memory (EC -> MDmc, abstract)]
	FMM.NC.PH.PER	Perirhinal Cortex	excitatory-glu	[of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract)]

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
NDM	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	excitatory-glu	[Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)]
	NDM.NC.AL.FPC	Lateral Frontopolar Cortex	excitatory-glu	[relationships (MD -> pMD, abstract)]

Thirdparty Circuits

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References

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