BrainRegionFMM NC PH MEC

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Medial Entorhinal Cortex

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This page covers biological details of component Medial Entorhinal Cortex. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> Rhinal Cortex (NC.PHA.RH) -> Entorhinal Cortex (FMM.NC.PH.ET) -> Medial Entorhinal Cortex (FMM.NC.PH.MEC) (see Mind Maps)
  • Type: cortex
  • Brain area: Forebrain - Memory Management Area
  • Brodmann ID: 28
  • Role: processor.memory.complex
  • Function: Memory consolidation, basic, view independent position
  • Notes to function: spatial input to HC; grid cells; path integration computations based on a global frame of reference, primarily using internally generated, self-motion cues and external input about environmental boundaries and scenes; provides hippocampus with coordinate system that underlies spatial context of experience

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Components

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Connectivity

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FMM.NC.PH.MEC.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FMM FMM.FT.HF.SUBD Distal Subiculum excitatory-glu Attractor Network in Hippocampus (SUB -> EC, abstract)
FMM.NC.PH.PAS Parasubiculum feedforward-glu (unknown reference)
FMM.NC.PH.POR Postrhinal Cortex feedforward-glu Entorhinal Cortex Inputs and Outputs (TFTH -> EC, abstract)
FMM.NC.PH.POS Postsubiculum feedforward-glu Head Direction Cell Circuit (PSUB -> EC, abstract)
FMM.NC.PH.PRS Presubiculum feedforward-glu Attractor Network in Hippocampus (PRESUB -> EC, abstract)
NCP NCP.NC.MPL.PSCG Posterior Cingulate Cortex feedforward-glu McNaughton Spatial Processing Network (PCGRSP -> EnthCortex, abstract)
NCP.NC.MPL.RSC Retrosplenial Cortex feedforward-glu McNaughton Spatial Processing Network (PCGRSP -> EnthCortex, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FMM FMM.FD.MB.MMB Medial Mammillary Nucleus excitatory-glu Mammillary bodies: two memory systems in one (MedialEC -> MMB, abstract)
FMM.FD.TH.AV Anteroventral Nucleus excitatory-glu Contributions of Diencephalon to Recognition Memory (EC -> AN, abstract)
FMM.FD.TH.LD Lateral Dorsal Nucleus of Thalamus excitatory-glu Contributions of Diencephalon to Recognition Memory (EC -> LD, abstract)
FMM.FT.HC.CA1P Proximal CA1 of Hippocampus excitatory-glu Neuronal projections in the hippocampus (ET -> CA1, abstract)
FMM.FT.HC.CA2 Dorsolateral Cornu Ammonis of Hippocampus excitatory-glu Amygdala and its network (EC -> HC, abstract)
FMM.FT.HC.CA3D Distal CA3 of Hippocampus excitatory-glu Neuronal projections in the hippocampus (ET -> CA3, abstract)
FMM.FT.HC.DG Dentate Gyrus excitatory-glu Neuronal projections in the hippocampus (ET -> DG, abstract)

Thirdparty Circuits

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References

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